Reactome | TAC1 [plasma membrane]

TAC1 [plasma membrane]

Stable Identifier

R-HSA-5668752

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

TNFRSF13B, Tumor necrosis factor receptor superfamily member 13B, TR13B_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:O14836 TNFRSF13B

Gene Names

TNFRSF13B, TACI

Chain

chain:1-293

Reference Genes

BioGPS Gene:23495 TNFRSF13B

COSMIC (genes):TNFRSF13B TNFRSF13B

CTD Gene:23495 TNFRSF13B

dbSNP Gene:23495 TNFRSF13B

ENSEMBL:ENSG00000240505 TNFRSF13B

HGNC:18153 TNFRSF13B

KEGG:hsa:23495 TNFRSF13B

Monarch:23495 TNFRSF13B

NCBI Gene:23495 TNFRSF13B

OMIM:604907 TNFRSF13B

UCSC:O14836 TNFRSF13B

Reference Transcript

RefSeq:NM_012452.3 TNFRSF13B

Other Identifiers

11738483_a_at

11738484_x_at

11748879_a_at

11760754_at

16841829

207641_PM_at

207641_at

23495

31410_at

3747509

3747511

3747512

3747513

3747514

3747523

3747524

3747525

3747526

3747528

3747529

3747530

3747532

3747533

3747534

3747536

7896723

8013061

A_23_P84705

GE54185

GO:0001782

GO:0002244

GO:0002250

GO:0002376

GO:0005515

GO:0005886

GO:0007166

GO:0016020

GO:0030154

GO:0030889

GO:0038023

HMNXSV003045992

ILMN_1759075

PH_hs_0039741

g6912693_3p_at

Participates

as a member of

TAC1,BCMA [plasma membrane] (Homo sapiens)

Inferred To

TNFRSF13B [plasma membrane] (Bos taurus)

TNFRSF13B [plasma membrane] (Canis familiaris)

TNFRSF13B [plasma membrane] (Gallus gallus)

TNFRSF13B [plasma membrane] (Sus scrofa)

Tnfrsf13b [plasma membrane] (Mus musculus)

TAC1 [plasma membrane] (Rattus norvegicus)

Cross References

RefSeq

NP_036584.1

Guide to Pharmacology - Targets

1885

ENSEMBL

ENSG00000240505, ENST00000261652, ENST00000583789, ENSP00000462952, ENSP00000261652

OpenTargets

ENSG00000240505

GeneCards

TNFRSF13B

HPA

ENSG00000240505-TNFRSF13B

PRO

O14836

Pharos - Targets

O14836

GlyGen

O14836

Orphanet

TNFRSF13B

PDB

1XUT, 1XU1

Interactors (8)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q99836 MYD88	8	MYD88 [cytosol] (R-HSA-166059) MYD88 [plasma membrane] (R-HSA-937017) MYD88 [endosome membrane] (R-HSA-975123) MyD88 E65del [cytosol] (R-HSA-5602598) MyD88 S34Y [cytosol] (R-HSA-5602521) MyD88 L93P [cytosol] (R-HSA-5602612) MyD88 E52del [cytosol] (R-HSA-5602451) MyD88 R196C [cytosol] (R-HSA-5602329)	0.692	12
UniProt:O75888 TNFSF13	3	p-T243-TNFSF13 [cytosol] (R-HSA-450619) p-T243-TNFSF13 [nucleoplasm] (R-HSA-450603) sAPRIL [extracellular region] (R-HSA-5676560)	0.609	2
UniProt:Q12933 TRAF2	5	TRAF2 [cytosol] (R-HSA-66370) PolyUb-TRAF2 [cytosol] (R-HSA-6782848) K63polyUb-TRAF2 [cytosol] (R-HSA-8862193) K63polyUb-TRAF2 [nucleoplasm] (R-HSA-8862194) TRAF2 [nucleoplasm] (R-HSA-8862199)	0.532	3
UniProt:P29597 TYK2	5	p-Y1054-TYK2 [cytosol] (R-HSA-1112598) p-Y1054,Y1055-TYK2 [cytosol] (R-HSA-909682) TYK2 [cytosol] (R-HSA-877348) p-TYK2 [cytosol] (R-HSA-8950424) p-Y-TYK2 [cytosol] (R-HSA-6784366)	0.527	2
UniProt:P56182 RRP1	1	RRP1 [nucleoplasm] (R-HSA-6792441)	0.527	2
UniProt:Q9P2N5 RBM27	1	RBM27 [nucleoplasm] (R-HSA-9935838)	0.527	2
UniProt:Q5T8P6 RBM26	1	RBM26 [nucleoplasm] (R-HSA-9935784)	0.527	3
UniProt:Q9Y4K3 TRAF6	8	TRAF6 [cytosol] (R-HSA-166366) K63polyUb-TRAF6 [cytosol] (R-HSA-2685681) K63polyUb-TRAF6 [plasma membrane] (R-HSA-936980) TRAF6 [plasma membrane] (R-HSA-936955) K63polyUb-TRAF6 [endosome membrane] (R-HSA-450227) TRAF6 [endosome membrane] (R-HSA-450272) PolyUb-TRAF6 [cytosol] (R-HSA-6782845) K48polyUb-TRAF6 [cytosol] (R-HSA-6783233)	0.462	2

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