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p-T243-TNFSF13 [nucleoplasm]
Stable Identifier
R-HSA-450603
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
APRIL with phosphothreonine 243, Tumor necrosis factor ligand superfamily member 13, TNFSF13
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Homo sapiens)
Regulation of mRNA stability by proteins that bind AU-rich elements (Homo sapiens)
HuR (ELAVL1) binds and stabilizes mRNA (Homo sapiens)
HuR binds the CRM1 nuclear export machinery (Homo sapiens)
HuR:APRIL:pp32:SET(SETalpha):Nup214(SETbeta):CRM1 [nucleoplasm] (Homo sapiens)
p-T243-TNFSF13 [nucleoplasm] (Homo sapiens)
p-T243-TNFSF13 [nucleoplasm] (Homo sapiens)
HuR:mRNA complex translocates from the nucleus to the cytosol (Homo sapiens)
HuR:APRIL:pp32:SET(SETalpha):Nup214(SETbeta):CRM1 [nucleoplasm] (Homo sapiens)
p-T243-TNFSF13 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:O75888 TNFSF13
Gene Names
TNFSF13, APRIL, TALL2, ZTNF2, UNQ383/PRO715
Chain
propeptide:1-104, chain:105-250
Reference Genes
BioGPS Gene:8741 TNFSF13
COSMIC (genes):TNFSF13 TNFSF13
CTD Gene:8741 TNFSF13
dbSNP Gene:8741 TNFSF13
ENSEMBL:ENSG00000161955 TNFSF13
ENSEMBL_homo_sapiens_GENE:ENSG00000161955.17 TNFSF13
HGNC:11928 TNFSF13
KEGG Gene (Homo sapiens):8741 TNFSF13
Monarch:8741 TNFSF13
NCBI Gene:8741 TNFSF13
OMIM:604472 TNFSF13
UCSC:O75888 TNFSF13
Reference Transcript
RefSeq:NM_172087.2 TNFSF13
RefSeq:NM_003808.3 TNFSF13
RefSeq:NM_001198624.1 TNFSF13
RefSeq:NM_001198623.1 TNFSF13
RefSeq:NM_172088.2 TNFSF13
Other Identifiers
11730090_a_at
11753321_a_at
209499_PM_x_at
209499_x_at
209500_PM_x_at
209500_x_at
210314_PM_x_at
210314_x_at
211495_PM_x_at
211495_x_at
35287_at
3708778
3708779
3708780
3708781
3708782
3708783
3708785
3708788
3708789
3708790
3708791
3708792
3708793
3708794
3708795
3708796
3708797
3708799
3708800
8741
GE54821
GO:0002376
GO:0005102
GO:0005125
GO:0005164
GO:0005515
GO:0005576
GO:0005615
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0006310
GO:0006955
GO:0007154
GO:0007165
GO:0008284
GO:0016020
GO:0023052
GO:0043226
GO:0048018
GO:0048298
GO:0048856
GO:0050896
GO:0070062
GO:0098772
HMNXSV003033399
Hs.54673.2.S1_3p_x_at
ILMN_1784264
ILMN_2399190
PH_hs_0003589
PH_hs_0031241
TC17002865.hg
g7328553_3p_a_at
g7328555_3p_a_at
Participates
as a component of
HuR:APRIL:pp32:SET(SETalpha):Nup214(SETbeta):CRM1 [nucleoplasm] (Homo sapiens)
as an input of
HuR binds the CRM1 nuclear export machinery (Homo sapiens)
Other forms of this molecule
p-T243-TNFSF13 [cytosol]
sAPRIL [extracellular region]
Inferred To
phospho-tnfsf13 [nucleoplasm]
(Danio rerio)
phospho-egr [nucleoplasm]
(Drosophila melanogaster)
Ghost homologue of p-T243-TNFSF13 [nucleoplasm]
(Gallus gallus)
phospho-Tnfsf13 [nucleoplasm]
(Mus musculus)
phospho-Tnfsf13 [nucleoplasm]
(Rattus norvegicus)
phospho-TNFSF13 [nucleoplasm]
(Bos taurus)
phospho-TNFSF13 [nucleoplasm]
(Canis familiaris)
phospho-TNFSF13 [nucleoplasm]
(Sus scrofa)
Modified Residues
Name
O-phospho-L-threonine at 243
Coordinate
243
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Cross References
RefSeq
NP_742084.1
,
NP_001185553.1
,
NP_742085.1
,
NP_001185552.1
,
NP_003799.1
OpenTargets
ENSG00000161955
HPA
ENSG00000161955-TNFSF13
GeneCards
O75888
Ensembl
ENSP00000379794
,
ENSP00000343505
,
ENST00000625791
,
ENSG00000161955
,
ENST00000349228
,
ENSP00000379792
,
ENSP00000314455
,
ENSP00000486052
,
ENST00000396542
,
ENST00000338784
,
ENST00000396545
PRO
O75888
Pharos - Targets
O75888
PDB
4ZCH
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