Reactome | GNB1 [photoreceptor disc membrane]

GNB1 [photoreceptor disc membrane]

Stable Identifier

R-HSA-55373

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

photoreceptor disc membrane

Synonyms

Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subunit 1, Transducin beta chain 1

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External Reference Information

External Reference

UniProt:P62873 GNB1

Gene Names

GNB1

Chain

initiator methionine:1, chain:2-340

Reference Genes

COSMIC (genes):GNB1 GNB1

dbSNP Gene:2782 GNB1

ENSEMBL:ENSG00000078369 GNB1

Participates

as a component of

GNB1:GNGT1 [photoreceptor disc membrane] (Homo sapiens)

Other forms of this molecule

Unfolded GNB1 [cytosol]

Partially folded GNB1 [cytosol]

GNB1 [plasma membrane]

GNB1 [cytosol]

Inferred To

gnb1b [photoreceptor disc membrane] (Danio rerio)

Gnb1 [photoreceptor disc membrane] (Bos taurus)

Gnb1 [photoreceptor disc membrane] (Mus musculus)

Gnb1 [photoreceptor disc membrane] (Rattus norvegicus)

GNB1 [photoreceptor disc membrane] (Canis familiaris)

GNB1 [photoreceptor disc membrane] (Sus scrofa)

gnb1 [photoreceptor disc membrane] (Xenopus tropicalis)

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.666	10
UniProt:Q13371 PDCL	2	p-S18,S19,S20,S25-PDCL [cytosol] (R-HSA-6814228) PDCL [cytosol] (R-HSA-6813727)	0.643	4
UniProt:P63211 GNGT1	3	GNGT1 [photoreceptor disc membrane] (R-HSA-55393) S-farn-GNGT1 [photoreceptor disc membrane] (R-HSA-2530520) GNGT1 [plasma membrane] (R-HSA-167428)	0.621	3
UniProt:P07237 P4HB	3	P4HB [endoplasmic reticulum lumen] (R-HSA-174692) p-P4HB [endoplasmic reticulum lumen] (R-HSA-8956902) HC53,56-P4HB [endoplasmic reticulum lumen] (R-HSA-3341287)	0.556	3
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104)	0.527	10
UniProt:P10636-8 MAPT	3	MAPT-8 [cytosol] (R-HSA-9619519) p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol] (R-HSA-9836400) p-S262,S356,S396-MAPT-8 [cytosol] (R-HSA-9619521)	0.527	4
UniProt:P10824 Gnai1	1	Guanine nucleotide-binding protein G(i), alpha-1 subunit [plasma membrane] (R-RNO-421889)	0.488	2

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