Reactome | AP1G2 [Golgi membrane]

AP1G2 [Golgi membrane]

Stable Identifier

R-HSA-5216197

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

Golgi membrane

Synonyms

AP-1 complex subunit gamma-like 2, AP1G2_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O75843 AP1G2

Gene Names

AP1G2

Chain

chain:1-785

Reference Genes

BioGPS Gene:8906 AP1G2

COSMIC (genes):AP1G2 AP1G2

CTD Gene:8906 Q86V28

dbSNP Gene:8906 AP1G2

ENSEMBL:ENSG00000213983 AP1G2

HGNC:556 AP1G2

KEGG:hsa:8906 AP1G2

Monarch:8906 AP1G2

NCBI Gene:8906 AP1G2

OMIM:603534 AP1G2

UCSC:O75843 AP1G2

Reference Transcript

Other Identifiers

11721535_a_at

11736578_a_at

16790943

201613_PM_s_at

201613_s_at

214341_PM_at

214341_at

226918_PM_at

226918_at

3557615

3557616

3557617

3557618

3557619

3557620

3557621

3557622

3557623

3557624

3557625

3557626

3557627

3557628

3557629

3557630

3557631

3557632

3557633

3557634

3557635

3557636

3557637

3557638

3557639

3557640

3557641

3557642

3557643

3557644

3557645

3557646

3557647

3557648

3557649

3557650

3557651

3557652

3557653

3557654

3557655

3557656

3557657

3557658

3557659

3557660

3557661

3557662

3557663

3557664

3557665

3557667

38798_s_at

38799_at

61374_at

7978066

8906

A_23_P2967

A_33_P3219279

GE808689

GO:0000139

GO:0005515

GO:0005768

GO:0005794

GO:0005798

GO:0006886

GO:0006896

GO:0010008

GO:0015031

GO:0016020

GO:0016192

GO:0030117

GO:0030121

GO:0030133

GO:0031410

GO:0035615

GO:0043226

GO:0045202

GO:0060090

GO:0097708

HMNXSV003017837

HMNXSV003019316

HMNXSV003024257

HMNXSV003028056

HMNXSV003042414

Hs.26714.0.A1_3p_at

Hs.8991.1.A1_3p_at

ILMN_1754179

ILMN_1758829

ILMN_2276598

PH_hs_0002360

PH_hs_0016624

TC14002205.hg

g12653494_3p_s_at

Participates

as a component of

AP1G2:HGS:CHMP2A [Golgi membrane] (Homo sapiens)

as an input of

AP1G2 binds HGS and CHMP2A (Homo sapiens)

Inferred To

Homologues of AP1G2 [Golgi membrane] (Plasmodium falciparum)

apl4 [Golgi membrane] (Schizosaccharomyces pombe)

Ap1g2 [Golgi membrane] (Mus musculus)

Ap1g2 [Golgi membrane] (Rattus norvegicus)

apg-1 [Golgi membrane] (Caenorhabditis elegans)

APL4 [Golgi membrane] (Saccharomyces cerevisiae)

ap1g1 [Golgi membrane] (Dictyostelium discoideum)

AP1G2 [Golgi membrane] (Bos taurus)

AP1G2 [Golgi membrane] (Canis familiaris)

AP1G2 [Golgi membrane] (Plasmodium falciparum)

AP1G2 [Golgi membrane] (Sus scrofa)

ap1g2 [Golgi membrane] (Danio rerio)

ap1g2 [Golgi membrane] (Xenopus tropicalis)

AP-1gamma [Golgi membrane] (Drosophila melanogaster)

Cross References

ENSEMBL

ENST00000397120, ENSG00000213983, ENSP00000312442, ENST00000308724, ENSP00000380309

OpenTargets

ENSG00000213983

GeneCards

AP1G2

HPA

ENSG00000213983-AP1G2

PRO

O75843

Pharos - Targets

O75843

GlyGen

O75843

PDB

3ZHF, 2YMT, 2E9G, 4BCX

Interactors (10)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P56377 AP1S2	5	AP1S2 [cytoplasmic vesicle membrane] (R-HSA-351188) AP1S2 [Golgi membrane] (R-HSA-350812) AP1S2 [lysosomal membrane] (R-HSA-432711) AP1S2 [trans-Golgi network membrane] (R-HSA-2130394) AP1S2 [cytosol] (R-HSA-167695)	0.643	4
UniProt:P03139-1 S			0.618	6
UniProt:Q96JJ7 TMX3	2	TMX3 [plasma membrane] (R-HSA-8848896) TMX3 [platelet alpha granule membrane] (R-HSA-8848889)	0.527	2
UniProt:P35442 THBS2	4	THBS2 [endoplasmic reticulum lumen] (R-HSA-5173187) glc-fuc-THBS2 [endoplasmic reticulum lumen] (R-HSA-5173234) O-fuc-THBS2 [endoplasmic reticulum lumen] (R-HSA-5173111) THBS2 [extracellular region] (R-HSA-66520)	0.527	2
UniProt:Q9C0D3 ZY11B			0.527	2
UniProt:Q6PD74 AAGAB			0.527	2
UniProt:Q96BY7 ATG2B			0.527	2
UniProt:Q6UWB1 IL27RA	4	IL27RA [plasma membrane] (R-HSA-448478) p-Y611-IL27RA [plasma membrane] (R-HSA-8950330) sIL27RA [extracellular region] (R-HSA-8950454) sIL27RA [cytoplasm] (R-HSA-8950653)	0.527	3
UniProt:Q96PK6 RBM14	1	RBM14 [nucleoplasm] (R-HSA-8938345)	0.527	2
UniProt:Q15276 RABEP1	1	RABEP1 [early endosome membrane] (R-HSA-2029004)	0.508	2

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