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AP1S2 [trans-Golgi network membrane]
Stable Identifier
R-HSA-2130394
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
trans-Golgi network membrane
Synonyms
AP-1 sigma 1B
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
MHC class II antigen presentation (Homo sapiens)
Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex (Homo sapiens)
AP-1 Clathrin coated nonameric complex [trans-Golgi network membrane] (Homo sapiens)
AP-1 Complex [trans-Golgi network membrane] (Homo sapiens)
AP1S1,2,3 [trans-Golgi network membrane] (Homo sapiens)
AP1S2 [trans-Golgi network membrane] (Homo sapiens)
TGN-lysosome vesicle uncoating and release of nonameric complex to lysosome (Homo sapiens)
TGN-lysosome vesicle with nonameric complex [trans-Golgi network membrane] (Homo sapiens)
AP-1 Complex [trans-Golgi network membrane] (Homo sapiens)
AP1S1,2,3 [trans-Golgi network membrane] (Homo sapiens)
AP1S2 [trans-Golgi network membrane] (Homo sapiens)
Translocation of TGN-lysosome vesicle to lysosome (Homo sapiens)
AP-1 Clathrin coated nonameric complex [trans-Golgi network membrane] (Homo sapiens)
AP-1 Complex [trans-Golgi network membrane] (Homo sapiens)
AP1S1,2,3 [trans-Golgi network membrane] (Homo sapiens)
AP1S2 [trans-Golgi network membrane] (Homo sapiens)
TGN-lysosome vesicle with nonameric complex [trans-Golgi network membrane] (Homo sapiens)
AP-1 Complex [trans-Golgi network membrane] (Homo sapiens)
AP1S1,2,3 [trans-Golgi network membrane] (Homo sapiens)
AP1S2 [trans-Golgi network membrane] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
trans-Golgi Network Vesicle Budding (Homo sapiens)
Lysosome Vesicle Biogenesis (Homo sapiens)
CLAT:AP1:CLVS bind PI(3,5)P2 (Homo sapiens)
CLAT:AP1:CLVS [trans-Golgi network membrane] (Homo sapiens)
AP1 complex [trans-Golgi network membrane] (Homo sapiens)
AP1S1,2,3 [trans-Golgi network membrane] (Homo sapiens)
AP1S2 [trans-Golgi network membrane] (Homo sapiens)
CLAT:AP1:CLVS:PI(3,5)P2 [clathrin-coated endocytic vesicle] (Homo sapiens)
CLAT:AP1:CLVS [trans-Golgi network membrane] (Homo sapiens)
AP1 complex [trans-Golgi network membrane] (Homo sapiens)
AP1S1,2,3 [trans-Golgi network membrane] (Homo sapiens)
AP1S2 [trans-Golgi network membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P56377 AP1S2
Gene Names
AP1S2, DC22
Chain
chain:1-157
Reference Genes
BioGPS Gene:8905 AP1S2
COSMIC (genes):AP1S2 AP1S2
CTD Gene:8905 AP1S2
dbSNP Gene:8905 AP1S2
ENSEMBL:ENSG00000182287 AP1S2
ENSEMBL_homo_sapiens_GENE:ENSG00000182287.15 AP1S2
HGNC:560 AP1S2
KEGG Gene (Homo sapiens):8905 AP1S2
Monarch:8905 AP1S2
NCBI Gene:8905 AP1S2
OMIM:300629 AP1S2
Reference Transcript
RefSeq:NM_003916.4 AP1S2
RefSeq:XM_011545599.1 AP1S2
RefSeq:XM_017029925.1 AP1S2
Other Identifiers
11730719_x_at
11756395_s_at
203299_PM_s_at
203299_s_at
203300_PM_x_at
203300_x_at
230264_PM_s_at
230264_s_at
3765126
3765127
4000705
4000706
4000707
4000708
4000709
4000734
4000735
4000738
4000739
4000740
4000741
41549_s_at
56267_at
8017210
8171481
8905
A_23_P217384
A_24_P190804
A_33_P3258782
GE54764
GO:0000139
GO:0005515
GO:0005764
GO:0005765
GO:0005768
GO:0005769
GO:0005773
GO:0005794
GO:0005829
GO:0005886
GO:0005905
GO:0006886
GO:0015031
GO:0016020
GO:0016192
GO:0030117
GO:0030119
GO:0030121
GO:0030659
GO:0031410
GO:0032588
GO:0035615
GO:0043226
GO:0043231
GO:0060090
GO:0060155
GO:1903232
HMNXSV003008679
HMNXSV003047417
Hs.40368.3.S1_3p_a_at
ILMN_1766411
ILMN_2120273
PH_hs_0003032
g12005731_3p_at
g4506956_3p_a_at
Participates
as a member of
AP1S1,2,3 [trans-Golgi network membrane] (Homo sapiens)
Other forms of this molecule
AP1S2 [cytoplasmic vesicle membrane]
AP1S2 [Golgi membrane]
AP1S2 [lysosomal membrane]
AP1S2 [cytosol]
Inferred To
AP-1sigma [trans-Golgi network membrane]
(Drosophila melanogaster)
LOC119868747 [trans-Golgi network membrane]
(Canis familiaris)
wu:fj40d12 [trans-Golgi network membrane]
(Danio rerio)
vas2 [trans-Golgi network membrane]
(Schizosaccharomyces pombe)
APS1 [trans-Golgi network membrane]
(Saccharomyces cerevisiae)
ap1s1 [trans-Golgi network membrane]
(Dictyostelium discoideum)
ap1s2 [trans-Golgi network membrane]
(Xenopus tropicalis)
aps-1 [trans-Golgi network membrane]
(Caenorhabditis elegans)
AP1S2 [trans-Golgi network membrane]
(Bos taurus)
AP1S2 [trans-Golgi network membrane]
(Gallus gallus)
AP1S2 [trans-Golgi network membrane]
(Sus scrofa)
Ap1s2 [trans-Golgi network membrane]
(Mus musculus)
Ap1s2 [trans-Golgi network membrane]
(Rattus norvegicus)
Cross References
RefSeq
XP_011543901.1
,
NP_003907.3
,
XP_016885414.1
OpenTargets
ENSG00000182287
GeneCards
P56377
HPA
ENSG00000182287-AP1S2
Ensembl
ENSG00000182287
,
ENST00000329235
,
ENSP00000328789
PRO
P56377
Pharos - Targets
P56377
Orphanet
16758
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O75843 AP1G2
1
AP1G2 [Golgi membrane]
(R-HSA-5216197)
0.643
4
UniProt:P56539 CAV3
1
CAV3 [plasma membrane]
(R-HSA-1368135)
0.527
2
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