Reactome | IL27RA [plasma membrane]

IL27RA [plasma membrane]

Stable Identifier

R-HSA-448478

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Interleukin-27 receptor subunit alpha, I27RA_HUMAN, WSX-1

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q6UWB1 IL27RA

Gene Names

IL27RA, CRL1, TCCR, WSX1, UNQ296/PRO336

Chain

signal peptide:1-32, chain:33-636

Reference Genes

BioGPS Gene:9466 IL27RA

COSMIC (genes):IL27RA IL27RA

CTD Gene:9466 IL27RA

dbSNP Gene:9466 IL27RA

ENSEMBL:ENSG00000104998 IL27RA

ENSEMBL_homo_sapiens_GENE:ENSG00000104998.4 IL27RA

ENSEMBL_homo_sapiens_GENE:ENSG00000288185.1 IL27RA

HGNC:17290 IL27RA

KEGG Gene (Homo sapiens):9466 IL27RA

Monarch:9466 IL27RA

NCBI Gene:9466 IL27RA

OMIM:605350 IL27RA

UCSC:Q6UWB1 IL27RA

Reference Transcript

RefSeq:NM_004843.3 IL27RA

Other Identifiers

11729821_at

16858941

205926_PM_at

205926_at

222062_PM_at

222062_at

37843_i_at

37844_at

3822552

3822553

3822555

3822556

3822558

3822559

3822561

3822563

3822564

3822565

3822566

3822567

3822568

3822569

3822570

3822571

3822572

3822573

3822575

48750_at

8026272

9466

A_23_P27606

A_24_P348326

GE80277

GO:0002376

GO:0002692

GO:0002827

GO:0002829

GO:0004888

GO:0005515

GO:0005886

GO:0006310

GO:0006955

GO:0007166

GO:0009897

GO:0012501

GO:0016020

GO:0019221

GO:0019955

GO:0023052

GO:0032700

GO:0032715

GO:0032720

GO:0032729

GO:0043235

GO:0043524

GO:0045509

GO:0048302

GO:0048856

GO:0048870

GO:0050830

GO:0060089

GO:0070106

GO:0098542

GO:2000317

GO:2000408

HMNXSV003038831

Hs.132781.1.A1_3p_at

ILMN_1688152

PH_hs_0007956

TC19000250.hg

g4759327_3p_x_at

Participates

as a component of

as an input of

Other forms of this molecule

p-Y611-IL27RA [plasma membrane]

sIL27RA [extracellular region]

sIL27RA [cytoplasm]

Inferred To

Ghost homologue of IL27RA [plasma membrane] (Gallus gallus)

Ghost homologue of IL27RA [plasma membrane] (Rattus norvegicus)

IL27RA [plasma membrane] (Bos taurus)

IL27RA [plasma membrane] (Canis familiaris)

IL27RA [plasma membrane] (Sus scrofa)

il27ra [plasma membrane] (Xenopus tropicalis)

Il27ra [plasma membrane] (Mus musculus)

Cross References

RefSeq

NP_004834.1

Guide to Pharmacology - Targets

2318

OpenTargets

ENSG00000104998

GeneCards

Q6UWB1

HPA

ENSG00000104998-IL27RA

Ensembl

ENST00000263379, ENSP00000500946, ENSG00000288185, ENSP00000263379, ENSG00000104998, ENST00000672064

PRO

Q6UWB1

Pharos - Targets

Q6UWB1

Orphanet

28711

PDB

7U7N, 7T5M, 8D85

Interactors (22)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q5J5C9 DEFB121	3	DEFB121(?-76) [extracellular region] (R-HSA-1471330) DEFB121(?-76) [Golgi lumen] (R-HSA-975806) DEFB121(1-76) [Golgi lumen] (R-HSA-1470037)	0.556	3
UniProt:Q96Q80 DERL3	1	DERL3 [endoplasmic reticulum membrane] (R-HSA-8866516)	0.556	3
UniProt:Q96JW4 SLC41A2	1	SLC41A2 [plasma membrane] (R-HSA-442666)	0.556	3
UniProt:P57739 CLDN2	2	CLDN2 [plasma membrane] (R-HSA-419994) CLDN2 [cell junction] (R-HSA-421235)	0.556	3
UniProt:Q8N3T1 GALNT15	1	GALNT15 [Golgi membrane] (R-HSA-913705)	0.556	3
UniProt:Q6N075 MFSD5			0.556	3
UniProt:Q96EC8 YIPF6	2	YIPF6 [Golgi membrane] (R-HSA-434346) YIPF6 [cytoplasmic vesicle membrane] (R-HSA-434199)	0.556	3
UniProt:Q6PL45-2 BRICD5			0.556	3
UniProt:Q3MIR4 CC50B			0.527	2
UniProt:P41273 TNFSF9	1	TNFSF9 [plasma membrane] (R-HSA-5667144)	0.527	2
UniProt:Q8N2A8 PLD6	2	PLD6 [endoplasmic reticulum membrane] (R-HSA-1498811) PLD6 [mitochondrial outer membrane] (R-HSA-5601898)	0.527	2
UniProt:Q9H3N1 TMX1			0.527	3
UniProt:Q9H1E5 TMX4			0.527	3
UniProt:Q9Y3P4 RHBD3			0.527	2
UniProt:Q9H819 DJC18			0.527	2
UniProt:Q9BZM4 ULBP3	1	ULBP3 [plasma membrane] (R-HSA-198076)	0.527	2
UniProt:Q6S8J3 POTEE	1	POTEE [cytosol] (R-HSA-9715126)	0.527	2
UniProt:P27824 CANX	2	CANX [lumenal side of endoplasmic reticulum membrane] (R-HSA-983091) CANX [endoplasmic reticulum lumen] (R-HSA-195906)	0.527	2
UniProt:O43286 B4GALT5	1	B4GALT5 [Golgi membrane] (R-HSA-1015832)	0.527	2
UniProt:P08240 SRPRA	1	SRPR [endoplasmic reticulum membrane] (R-HSA-264970)	0.527	2
UniProt:O75843 AP1G2	1	AP1G2 [Golgi membrane] (R-HSA-5216197)	0.527	3
UniProt:P0DTD1-PRO_0000449624 REP			0.488	2