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IL2RG:JAK3 [plasma membrane]
Stable Identifier
R-HSA-451911
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Signaling by Interleukins (Homo sapiens)
Interleukin-2 family signaling (Homo sapiens)
Interleukin receptor SHC signaling (Homo sapiens)
Gab2 binds the p85 subunit of Class 1A PI3 kinases (Homo sapiens)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:p(Y)-GAB2 [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2:p85-containing Class 1 PI3Ks [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p(Y338) beta subunit:p-SHC:GRB2:GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:p(Y)-GAB2 [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
Phosphorylated SHC recruits GRB2:SOS1 (Homo sapiens)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
Interleukin receptor complexes with activated SHC1:GRB2:SOS1 [plasma membrane] (Homo sapiens)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
Phosphorylated SHC1 recruits GRB2:GAB2 (Homo sapiens)
Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:GAB2 [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
Phosphorylated SHC1 recruits SHIP (Homo sapiens)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
Interleukin receptor complexes with activated SHC1:SHIP1,2 [plasma membrane] (Homo sapiens)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
SHC1 mediates cytokine-induced phosphorylation of GAB2 (Homo sapiens)
Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:GAB2 [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:p(Y)-GAB2 [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
The SHC1:SHIP1 complex is stabilized by GRB2 (Homo sapiens)
Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Homo sapiens)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
Interleukin receptor complexes with activated SHC1:SHIP:GRB2 [plasma membrane] (Homo sapiens)
Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Homo sapiens)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
Interleukin-15 signaling (Homo sapiens)
IL15 binds IL2RB:JAK1 and IL2RG:JAK3 (Homo sapiens)
IL15:IL2RB:JAK1:IL2RG:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
IL15:IL15RA binds IL2RB:JAK1 and IL2RG:JAK3 (Homo sapiens)
IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
IL15:IL15RA:IL2RB:JAK1:IL2RG:JAK3 translocates from the plasma membrane to the endosome (Homo sapiens)
IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 phosphorylates JAK3 and JAK1 (Homo sapiens)
IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
Interleukin-2 signaling (Homo sapiens)
IL2RG binds JAK3 (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
Interleukin-2: IL2 receptor alpha:beta binds IL2 receptor gamma subunit (Homo sapiens)
IL2:IL2R trimer:JAK1:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
JAK1 phosphorylates Y338, Y392 and Y510 of IL2RB (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
IL2:IL2R trimer:p-JAK1:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
Phosphorylated STAT5 is released (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,Y392, Y510) beta subunit:p-JAK1:JAK3:p-STAT5 [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
Phosphorylation of IL2RB Y338 enables SHC recruitment (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:SHC [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
Phosphorylation of IL2RB Y338, Y392 or Y510 enables STAT recruitment (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3:STAT5 [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
Recruited STAT5 is phosphorylated (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3:STAT5 [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,Y392, Y510) beta subunit:p-JAK1:JAK3:p-STAT5 [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
SHC1 bound to IL2 receptor is phosphorylated (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:SHC [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
SYK binds IL2RB (Homo sapiens)
IL2:IL2R trimer:p-JAK1:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
IL2:IL2R trimer:p-JAK1:JAK3:SYK [plasma membrane] (Homo sapiens)
IL2:IL2R trimer:p-JAK1:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
SYK is a substrate for JAK1 (Homo sapiens)
IL2:IL2R trimer:p-JAK1:JAK3:SYK [plasma membrane] (Homo sapiens)
IL2:IL2R trimer:p-JAK1:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
IL2:IL2R trimer:p-JAK1:JAK3:p-SYK [plasma membrane] (Homo sapiens)
IL2:IL2R trimer:p-JAK1:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
Within the IL-2R complex JAK3 phosphorylates JAK1 (Homo sapiens)
IL2:IL2R trimer:JAK1:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
IL2:IL2R trimer:p-JAK1:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
Interleukin-21 signaling (Homo sapiens)
IL21 receptor JAK phosphorylation (Homo sapiens)
IL21:IL21R:JAK1:IL2RG:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
IL21:IL21R:JAK1 binds IL2RG:JAK3 (Homo sapiens)
IL21:IL21R:JAK1:IL2RG:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
Interleukin-9 signaling (Homo sapiens)
IL2RG binds JAK3 (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
IL9 binds IL9R:JAK1 and IL2RG:JAK3 (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
IL9:IL9R:JAK1:IL2RG:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
IL9:IL9R:JAK1:IL2RG:JAK3 phosphorylates JAK3 (Homo sapiens)
IL9:IL9R:JAK1:IL2RG:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
Interleukin-3, Interleukin-5 and GM-CSF signaling (Homo sapiens)
Interleukin receptor SHC signaling (Homo sapiens)
Gab2 binds the p85 subunit of Class 1A PI3 kinases (Homo sapiens)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:p(Y)-GAB2 [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2:p85-containing Class 1 PI3Ks [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p(Y338) beta subunit:p-SHC:GRB2:GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:p(Y)-GAB2 [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
Phosphorylated SHC recruits GRB2:SOS1 (Homo sapiens)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
Interleukin receptor complexes with activated SHC1:GRB2:SOS1 [plasma membrane] (Homo sapiens)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
Phosphorylated SHC1 recruits GRB2:GAB2 (Homo sapiens)
Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:GAB2 [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
Phosphorylated SHC1 recruits SHIP (Homo sapiens)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
Interleukin receptor complexes with activated SHC1:SHIP1,2 [plasma membrane] (Homo sapiens)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
SHC1 mediates cytokine-induced phosphorylation of GAB2 (Homo sapiens)
Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:GAB2 [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:p(Y)-GAB2 [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
The SHC1:SHIP1 complex is stabilized by GRB2 (Homo sapiens)
Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Homo sapiens)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
Interleukin receptor complexes with activated SHC1:SHIP:GRB2 [plasma membrane] (Homo sapiens)
Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Homo sapiens)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
Interleukin-4 and Interleukin-13 signaling (Homo sapiens)
IL2RG binds JAK3 (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
IL4:IL4R:JAK2 binds IL2RG:JAK3 (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
IL4:IL4R:JAK2:IL2RG:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
IL4R, IL2RG, JAK1 in IL4-bound IL4R1:JAK1 are phosphorylated (Homo sapiens)
IL4:IL4R:JAK2:IL2RG:JAK3:JAK1 [plasma membrane] (Homo sapiens)
IL4:IL4R:JAK2:IL2RG:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
JAK1 binds IL4R in IL4-bound IL4R1 (Homo sapiens)
IL4:IL4R:JAK2:IL2RG:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
IL4:IL4R:JAK2:IL2RG:JAK3:JAK1 [plasma membrane] (Homo sapiens)
IL4:IL4R:JAK2:IL2RG:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
Interleukin-7 signaling (Homo sapiens)
IL2RG binds JAK3 (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
IL7:IL7R:JAK1 binds IL2RG:JAK3 (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
IL7:IL7R:JAK1:IL2RG:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
JAK3 in IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3 is phosphorylated (Homo sapiens)
IL7:IL7R:JAK1:IL2RG:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
Signal Transduction (Homo sapiens)
MAPK family signaling cascades (Homo sapiens)
MAPK1/MAPK3 signaling (Homo sapiens)
RAF/MAP kinase cascade (Homo sapiens)
RAS GEFs promote RAS nucleotide exchange (Homo sapiens)
RAS GEFs [plasma membrane] (Homo sapiens)
Interleukin receptor complexes with activated SHC1:GRB2:SOS1 [plasma membrane] (Homo sapiens)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Homo sapiens)
IL2RG:JAK3 [plasma membrane] (Homo sapiens)
Participants
components
IL2RG [plasma membrane]
(Homo sapiens)
JAK3 [cytosol]
(Homo sapiens)
Participates
as a component of
IL15:IL2RB:JAK1:IL2RG:JAK3 [plasma membrane] (Homo sapiens)
IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 [plasma membrane] (Homo sapiens)
IL9:IL9R:JAK1:IL2RG:JAK3 [plasma membrane] (Homo sapiens)
IL21:IL21R:JAK1:IL2RG:JAK3 [plasma membrane] (Homo sapiens)
IL7:IL7R:JAK1:IL2RG:JAK3 [plasma membrane] (Homo sapiens)
IL4:IL4R:JAK2:IL2RG:JAK3 [plasma membrane] (Homo sapiens)
IL2:IL2R trimer:JAK1:JAK3 [plasma membrane] (Homo sapiens)
IL2:IL2R trimer:p-JAK1:JAK3 [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Homo sapiens)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Homo sapiens)
as an input of
IL15 binds IL2RB:JAK1 and IL2RG:JAK3 (Homo sapiens)
IL15:IL15RA binds IL2RB:JAK1 and IL2RG:JAK3 (Homo sapiens)
IL9 binds IL9R:JAK1 and IL2RG:JAK3 (Homo sapiens)
IL21:IL21R:JAK1 binds IL2RG:JAK3 (Homo sapiens)
IL7:IL7R:JAK1 binds IL2RG:JAK3 (Homo sapiens)
IL4:IL4R:JAK2 binds IL2RG:JAK3 (Homo sapiens)
Interleukin-2: IL2 receptor alpha:beta binds IL2 receptor gamma subunit (Homo sapiens)
as an output of
IL2RG binds JAK3 (Homo sapiens)
Inferred To
IL2RG:JAK3 [plasma membrane]
(Bos taurus)
IL2RG:JAK3 [plasma membrane]
(Canis familiaris)
IL2RG:JAK3 [plasma membrane]
(Danio rerio)
IL2RG:JAK3 [plasma membrane]
(Gallus gallus)
IL2RG:JAK3 [plasma membrane]
(Mus musculus)
IL2RG:JAK3 [plasma membrane]
(Rattus norvegicus)
IL2RG:JAK3 [plasma membrane]
(Sus scrofa)
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