Reactome | IL12A [extracellular region]

IL12A [extracellular region]

Stable Identifier

R-HSA-447212

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

IL12p35, IL12-p35, Interleukin-12 subunit alpha, IL12A_HUMAN

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External Reference Information

External Reference

UniProt:P29459 IL12A

Gene Names

IL12A, NKSF1

Chain

signal peptide:1-22, chain:23-219

Reference Genes

BioGPS Gene:3592 IL12A

COSMIC (genes):IL12A IL12A

CTD Gene:3592 IL12A

dbSNP Gene:3592 IL12A

ENSEMBL:ENSG00000168811 IL12A

ENSEMBL:ENSG00000168811.8 IL12A

HGNC:5969 IL12A

KEGG Gene (Homo sapiens):3592 IL12A

Monarch:3592 IL12A

NCBI Gene:3592 IL12A

OMIM:161560 IL12A

UCSC:P29459 IL12A

Reference Transcript

RefSeq:NM_000882.3 IL12A

Other Identifiers

11756769_a_at

16947532

2650068

2650069

2650070

2650071

2650073

2650075

2650077

2650078

2650079

2650080

2650081

2650082

33955_at

3592

7896725

8083690

A_14_P202111

A_23_P91943

GE519812

GO:0001916

GO:0002376

GO:0002860

GO:0005125

GO:0005143

GO:0005515

GO:0005576

GO:0005615

GO:0005768

GO:0005783

GO:0005788

GO:0006955

GO:0007155

GO:0008083

GO:0009615

GO:0010224

GO:0012501

GO:0016477

GO:0023052

GO:0031410

GO:0031906

GO:0032496

GO:0032700

GO:0032729

GO:0032816

GO:0032946

GO:0034393

GO:0035722

GO:0036211

GO:0042163

GO:0042531

GO:0043226

GO:0043514

GO:0045513

GO:0045785

GO:0045954

GO:0046982

GO:0048018

GO:0048662

GO:0048856

GO:0048870

GO:0050671

GO:0050709

GO:0050830

GO:0051135

GO:0097191

GO:0098542

GO:0098586

GO:0098772

GO:1900747

GO:1903588

GO:2000510

HMNXSV003038494

ILMN_1671353

M65291_at

PH_hs_0000076

TC03000870.hg

g4504638_3p_at

Participates

as a component of

as a member of

IL10-downregulated extracellular proteins [extracellular region] (Homo sapiens)

Other forms of this molecule

IL12A [Golgi lumen]

IL12A [endoplasmic reticulum lumen]

IL12A [late endosome lumen]

Inferred To

Ghost homologue of IL12A [extracellular region] (Bos taurus)

Ghost homologue of IL12A [extracellular region] (Canis familiaris)

Ghost homologue of IL12A [extracellular region] (Danio rerio)

Ghost homologue of IL12A [extracellular region] (Gallus gallus)

Ghost homologue of IL12A [extracellular region] (Mus musculus)

Ghost homologue of IL12A [extracellular region] (Rattus norvegicus)

Ghost homologue of IL12A [extracellular region] (Sus scrofa)

Cross References

RefSeq

NP_000873.2

OpenTargets

ENSG00000168811

HPA

ENSG00000168811-IL12A

GeneCards

P29459

Ensembl

ENSP00000514529, ENST00000699704, ENSG00000168811

PRO

P29459

Pharos - Targets

P29459

Orphanet

19315

PDB

1F45, 3HMX

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P29460 IL12B	5	IL12B [extracellular region] (R-HSA-447181) IL12B [endoplasmic reticulum lumen] (R-HSA-8950126) IL12B [late endosome lumen] (R-HSA-8950675) IL12B [Golgi lumen] (R-HSA-8950359) IL12B [cytosol] (R-HSA-8950760)	0.609	2

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