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CNOT11 [cytosol]
Stable Identifier
R-HSA-429981
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Uncharacterized protein C2orf29, C2orf29, CB029_HUMAN
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Maternal to zygotic transition (MZT) (Homo sapiens)
M-decay: degradation of maternal mRNAs by maternally stored factors (Homo sapiens)
BTG4 binds CNOT7 of the CCR4-NOT complex, PABPN1L, and eIF4E of the mRNP (Homo sapiens)
CCR4-NOT Complex (CNOT7) [cytosol] (Homo sapiens)
CNOT11 [cytosol] (Homo sapiens)
CCR4-NOT:BTG4:PABPN1L:mRNP [cytosol] (Homo sapiens)
CCR4-NOT Complex (CNOT7) [cytosol] (Homo sapiens)
CNOT11 [cytosol] (Homo sapiens)
CCR4-NOT deadenylates mRNA in CCR4-NOT:BTG4:PABPN1L:mRNP (Homo sapiens)
CCR4-NOT:BTG4:PABPN1L:deadenylated mRNP [cytosol] (Homo sapiens)
CCR4-NOT Complex (CNOT7) [cytosol] (Homo sapiens)
CNOT11 [cytosol] (Homo sapiens)
CCR4-NOT:BTG4:PABPN1L:mRNP [cytosol] (Homo sapiens)
CCR4-NOT Complex (CNOT7) [cytosol] (Homo sapiens)
CNOT11 [cytosol] (Homo sapiens)
CCR4-NOT(CNOT6L) deadenylates mRNA in CCR4-NOT(CNOT6L):ZFP36L2:mRNA (Homo sapiens)
CCR4-NOT(CNOT6L):ZFP36L2:deadenylated mRNA [cytosol] (Homo sapiens)
CCR4-NOT Complex (CNOT6L) [cytosol] (Homo sapiens)
CNOT11 [cytosol] (Homo sapiens)
CCR4-NOT(CNOT6L):ZFP36L2:mRNA [cytosol] (Homo sapiens)
CCR4-NOT Complex (CNOT6L) [cytosol] (Homo sapiens)
CNOT11 [cytosol] (Homo sapiens)
ZFP36L2 binds CNOT6L of CCR4-CNOT complex and an AU-rich element in mRNA (Homo sapiens)
CCR4-NOT Complex (CNOT6L) [cytosol] (Homo sapiens)
CNOT11 [cytosol] (Homo sapiens)
CCR4-NOT(CNOT6L):ZFP36L2:mRNA [cytosol] (Homo sapiens)
CCR4-NOT Complex (CNOT6L) [cytosol] (Homo sapiens)
CNOT11 [cytosol] (Homo sapiens)
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional Regulation by TP53 (Homo sapiens)
TP53 Regulates Transcription of Cell Cycle Genes (Homo sapiens)
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain (Homo sapiens)
BTG2 binds CCR4-NOT complex (Homo sapiens)
BTG2:CCR4-NOT [cytosol] (Homo sapiens)
CCR4-NOT Complex [cytosol] (Homo sapiens)
CNOT11 [cytosol] (Homo sapiens)
CCR4-NOT Complex [cytosol] (Homo sapiens)
CNOT11 [cytosol] (Homo sapiens)
Metabolism of RNA (Homo sapiens)
Deadenylation-dependent mRNA decay (Homo sapiens)
Deadenylation of mRNA (Homo sapiens)
CCR4-NOT complex deadenylates mRNA (Homo sapiens)
CCR4-NOT Complex [cytosol] (Homo sapiens)
CNOT11 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9UKZ1 CNOT11
Gene Names
CNOT11, C2orf29, C40
Chain
chain:1-510
Reference Genes
BioGPS Gene:55571 CNOT11
COSMIC (genes):CNOT11 CNOT11
CTD Gene:55571 CNOT11
dbSNP Gene:55571 CNOT11
ENSEMBL:ENSG00000158435 CNOT11
ENSEMBL_homo_sapiens_GENE:ENSG00000158435.8 CNOT11
HGNC:25217 CNOT11
KEGG Gene (Homo sapiens):55571 CNOT11
Monarch:55571 CNOT11
NCBI Gene:55571 CNOT11
OMIM:620509 CNOT11
UCSC:Q9UKZ1 CNOT11
Reference Transcript
RefSeq:NM_017546.4 CNOT11
Other Identifiers
11719244_s_at
16883552
224695_PM_at
224695_at
2496629
2496630
2496631
2496635
2496636
2496641
2496643
2496645
2496650
2496652
2496653
2496654
45752_at
55571
8043937
82492_at
A_14_P103360
A_23_P108761
GE87040
GO:0000289
GO:0003674
GO:0005515
GO:0005634
GO:0005737
GO:0005829
GO:0006417
GO:0016071
GO:0030014
GO:0031047
GO:0043226
HMNXSV003004616
Hs.30819.0.S2_3p_at
ILMN_1708906
PH_hs_0002629
TC02000615.hg
TC02003441.hg
Participates
as a component of
CCR4-NOT Complex (CNOT6L) [cytosol] (Homo sapiens)
CCR4-NOT Complex (CNOT7) [cytosol] (Homo sapiens)
CCR4-NOT Complex [cytosol] (Homo sapiens)
Inferred To
CNOT11 [cytosol]
(Bos taurus)
CNOT11 [cytosol]
(Canis familiaris)
CNOT11 [cytosol]
(Gallus gallus)
CNOT11 [cytosol]
(Sus scrofa)
Ghost homologue of CNOT11 [cytosol]
(Xenopus tropicalis)
cnot11 [cytosol]
(Danio rerio)
cnot11 [cytosol]
(Dictyostelium discoideum)
Cnot11 [cytosol]
(Mus musculus)
Cnot11 [cytosol]
(Rattus norvegicus)
Cross References
RefSeq
NP_060016.3
OpenTargets
ENSG00000158435
HPA
ENSG00000158435-CNOT11
GeneCards
Q9UKZ1
Ensembl
ENSG00000158435
,
ENST00000289382
,
ENSP00000289382
PRO
Q9UKZ1
Pharos - Targets
Q9UKZ1
PDB
8FY3
,
8BFJ
,
8BFI
,
8BFH
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q92600 RQCD1
2
RQCD1 [cytosol]
(R-HSA-430029)
RQCD1 [nucleoplasm]
(R-HSA-6810130)
0.638
4
UniProt:Q9BXI6 TBC1D10A
2
TBC1D10A [cytosol]
(R-HSA-8854139)
TBC1D10A [microvillus]
(R-HSA-8854143)
0.527
2
UniProt:Q14192 FHL2
1
FHL2 [nucleoplasm]
(R-HSA-561161)
0.527
3
UniProt:P09237 MMP7
6
MMP7(18-94) [extracellular region]
(R-HSA-1604729)
MMP7(51-94) [extracellular region]
(R-HSA-1604760)
MMP7(18-50) [extracellular region]
(R-HSA-1604759)
MMP7(95-267) [extracellular region]
(R-HSA-1442479)
MMP7(18-267) [extracellular region]
(R-HSA-1604734)
MMP7(51-267) [extracellular region]
(R-HSA-1604766)
0.527
3
UniProt:P47756 CAPZB
1
CAPZB [cytosol]
(R-HSA-879409)
0.527
3
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