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MMP7(51-267) [extracellular region]
Stable Identifier
R-HSA-1604766
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
MMP7 intermediate form, Matrilysin-1, MMP7_HUMAN, MMP7
Locations in the PathwayBrowser
Expand all
Extracellular matrix organization (Homo sapiens)
Degradation of the extracellular matrix (Homo sapiens)
Activation of Matrix Metalloproteinases (Homo sapiens)
Autocatalytic activation of MMP7 (Homo sapiens)
MMP7(51-267) [extracellular region] (Homo sapiens)
Initial activation of proMMP7 by trypsin (Homo sapiens)
MMP7(51-267) [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:P09237 MMP7
Gene Names
MMP7, MPSL1, PUMP1
Chain
signal peptide:1-17, propeptide:18-94, chain:95-267
Reference Genes
BioGPS Gene:4316 MMP7
COSMIC (genes):MMP7 MMP7
CTD Gene:4316 MMP7
dbSNP Gene:4316 MMP7
ENSEMBL:ENSG00000137673 MMP7
ENSEMBL_homo_sapiens_GENE:ENSG00000137673 MMP7
HGNC:7174 MMP7
KEGG Gene (Homo sapiens):4316 MMP7
Monarch:4316 MMP7
NCBI Gene:4316 MMP7
OMIM:178990 MMP7
UCSC:P09237 MMP7
Reference Transcript
RefSeq:NM_002423.4 MMP7
Other Identifiers
0001400605
11744030_a_at
11744031_at
11756074_a_at
16743647
1MMP
1MMQ
1MMR
204259_at
25869
2DDY
2MZE
2MZH
2MZI
2Y6C
2Y6D
3388674
3388675
3388676
3388677
3388678
3388681
3388682
3388683
3388684
3388685
3388686
4316
51358
5UE2
5UE5
668_s_at
7951217
A_23_P52761
AAC37543
AAH03635
AAV40839
CAA30678
CAA77942
CAB025869
CCDS8317
ENSG00000137673
ENSP00000260227
ENST00000260227
EntrezGene:4316
GE60350
GO:0000003
GO:0002376
GO:0002779
GO:0003674
GO:0004222
GO:0004252
GO:0005515
GO:0005575
GO:0005576
GO:0005615
GO:0005623
GO:0006508
GO:0006810
GO:0006950
GO:0007568
GO:0008150
GO:0008201
GO:0008233
GO:0008237
GO:0008270
GO:0009056
GO:0009986
GO:0016787
GO:0022617
GO:0030198
GO:0030574
GO:0031012
GO:0031667
GO:0043167
GO:0043226
GO:0044849
GO:0046872
GO:0060135
GO:0070062
GO:0071260
HGNC:7174
HPA051358
ILMN_1685403
ILMN_2192072
IPR001818
IPR002477
IPR006026
IPR021158
IPR021190
IPR024079
IPR028707
IPR033739
IPR036365
L22524_s_at
MIM:178990
MMP7
MMP7-201
NM_002423
NP_002414
PF00413
PF01471
PH_hs_0027041
PR00138
SM00235
TC11002228.hg
uc001phb.4
UPI00000422BD
Participant Of
input
Autocatalytic activation of MMP7
output
Initial activation of proMMP7 by trypsin
Other forms of this molecule
MMP7(18-94) [extracellular region]
MMP7(18-50) [extracellular region]
MMP7(18-267) [extracellular region]
MMP7(51-94) [extracellular region]
MMP7(95-267) [extracellular region]
Inferred To
MMP7(51-267) [extracellular region] (Arabidopsis thaliana)
MMP7(51-267) [extracellular region] (Bos taurus)
MMP7(51-267) [extracellular region] (Danio rerio)
MMP7(51-267) [extracellular region] (Drosophila melanogaster)
MMP7(51-267) [extracellular region] (Gallus gallus)
MMP7(51-267) [extracellular region] (Mus musculus)
MMP7(51-267) [extracellular region] (Oryza sativa)
MMP7(51-267) [extracellular region] (Rattus norvegicus)
MMP7(51-267) [extracellular region] (Sus scrofa)
MMP7(51-267) [extracellular region] (Taeniopygia guttata)
MMP7(51-267) [extracellular region] (Xenopus tropicalis)
Homologues of MMP7(51-267) [extracellular region] (Arabidopsis thaliana)
Homologues of MMP7(51-267) [extracellular region] (Oryza sativa)
Homologues of MMP7(51-267) [extracellular region] (Xenopus tropicalis)
Cross References
RefSeq
NP_002414.1
ZINC - World Drugs
MMP7_HUMAN
OpenTargets
ENSG00000137673
GeneCards
P09237
ZINC - Substances
MMP7_HUMAN
DOCK Blaster
2Y6D
,
2Y6C
,
1MMP
,
1MMQ
,
1MMR
ZINC target
P09237
PRO
P09237
BRENDA (Homo sapiens)
3.4.24.23
ZINC - Predictions - Purchasable
MMP7_HUMAN
PDB
2MZH
,
2DDY
,
5UE2
,
5UE5
,
2MZI
,
1MMR
,
2Y6C
,
2MZE
,
1MMQ
,
1MMP
,
2Y6D
HMDB Protein
HMDBP02928
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P17931 LGALS3
3
LGALS3 [plasma membrane]
(R-HSA-879445)
LGALS3 [ficolin-1-rich granule membrane]
(R-HSA-6803307)
LGALS3 [secretory granule membrane]
(R-HSA-6803327)
0.489
5
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