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CNOT2 [cytosol]
Stable Identifier
R-HSA-429902
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
CCR4-NOT transcription complex subunit 2, CNOT2_HUMAN
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional Regulation by TP53 (Homo sapiens)
TP53 Regulates Transcription of Cell Cycle Genes (Homo sapiens)
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain (Homo sapiens)
BTG2 binds CCR4-NOT complex (Homo sapiens)
BTG2:CCR4-NOT [cytosol] (Homo sapiens)
CCR4-NOT Complex [cytosol] (Homo sapiens)
CNOT2 [cytosol] (Homo sapiens)
CCR4-NOT Complex [cytosol] (Homo sapiens)
CNOT2 [cytosol] (Homo sapiens)
Metabolism of RNA (Homo sapiens)
Deadenylation-dependent mRNA decay (Homo sapiens)
Deadenylation of mRNA (Homo sapiens)
CCR4-NOT complex deadenylates mRNA (Homo sapiens)
CCR4-NOT Complex [cytosol] (Homo sapiens)
CNOT2 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9NZN8 CNOT2
Gene Names
CNOT2, CDC36, NOT2, HSPC131, MSTP046
Chain
chain:1-540
Reference Genes
BioGPS Gene:4848 CNOT2
COSMIC (genes):CNOT2 CNOT2
CTD Gene:4848 CNOT2
dbSNP Gene:4848 CNOT2
ENSEMBL:ENSG00000111596 CNOT2
HGNC:7878 CNOT2
KEGG Gene (Homo sapiens):4848 CNOT2
Monarch:4848 CNOT2
NCBI Gene:4848 CNOT2
OMIM:604909 CNOT2
UCSC:Q9NZN8 CNOT2
Reference Transcript
RefSeq:NM_001199303.1 CNOT2
RefSeq:NM_014515.5 CNOT2
RefSeq:NM_001199302.1 CNOT2
RefSeq:XM_011538399.1 CNOT2
Other Identifiers
0006380253
0106020167
11734936_a_at
11734937_a_at
11757803_x_at
217798_PM_at
217798_at
222182_PM_s_at
222182_s_at
33861_at
3421902
3421903
3421904
3421905
3421906
3421907
3421908
3421909
3421910
3421911
3421912
3421913
3421921
3421922
3421934
3421936
3421937
3421943
3421944
3421945
3421946
3421947
3421948
3421949
3421950
3421951
3421952
3421953
3421954
3421955
3421956
3421957
3421958
3421959
3421960
3421962
3421965
3421968
3421972
3421973
3421974
3421975
3421976
3421977
3421978
4848
72303_at
7957106
90977_at
A_19_P00328397
A_23_P162336
A_23_P421147
A_24_P8049
A_33_P3287690
GE81936
GO:0000122
GO:0000289
GO:0000932
GO:0001222
GO:0001829
GO:0003674
GO:0003712
GO:0004518
GO:0004535
GO:0005515
GO:0005575
GO:0005622
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0005886
GO:0006355
GO:0006357
GO:0006412
GO:0006417
GO:0007165
GO:0008134
GO:0008150
GO:0009056
GO:0009058
GO:0009790
GO:0010606
GO:0016020
GO:0022607
GO:0030014
GO:0030015
GO:0030154
GO:0031047
GO:0032991
GO:0033147
GO:0034641
GO:0034655
GO:0043226
GO:0048646
GO:0048856
GO:0090503
GO:2000036
HMNXSV003024520
HMNXSV003025484
Hs.239720.0.S2_3p_at
ILMN_1772651
PH_hs_0031951
TC12000620.hg
TC12002443.hg
Participates
as a component of
CCR4-NOT Complex [cytosol] (Homo sapiens)
Inferred To
Ghost homologue of CNOT2 [cytosol]
(Canis familiaris)
Cnot2 [cytosol]
(Mus musculus)
Cnot2 [cytosol]
(Rattus norvegicus)
cnot2 [cytosol]
(Danio rerio)
cnot2 [cytosol]
(Xenopus tropicalis)
CNOT2 [cytosol]
(Bos taurus)
CNOT2 [cytosol]
(Dictyostelium discoideum)
CNOT2 [cytosol]
(Gallus gallus)
CNOT2 [cytosol]
(Sus scrofa)
Cross References
RefSeq
NP_001186232.1
,
NP_001186231.1
,
XP_011536701.1
,
NP_055330.1
OpenTargets
ENSG00000111596
GeneCards
Q9NZN8
HPA
ENSG00000111596-CNOT2
Ensembl
ENSP00000448883
,
ENSP00000412091
,
ENST00000229195
,
ENST00000418359
,
ENSP00000229195
,
ENST00000551043
,
ENSG00000111596
,
ENSP00000449260
,
ENST00000551483
PRO
Q9NZN8
Pharos - Targets
Q9NZN8
Orphanet
28625
PDB
4C0D
,
5FU7
,
4C0F
,
5FU6
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P41182 BCL6
1
BCL6 [nucleoplasm]
(R-HSA-5223066)
0.556
3
UniProt:P63244 RACK1
1
GNB2L1 [cytosol]
(R-HSA-5626956)
0.556
3
UniProt:Q92600 CNOT9
2
RQCD1 [nucleoplasm]
(R-HSA-6810130)
RQCD1 [cytosol]
(R-HSA-430029)
0.508
2
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