Reactome | MMP7(51-94) [extracellular region]

MMP7(51-94) [extracellular region]

Stable Identifier

R-HSA-1604760

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

MMP7 fragment 51-94, Matrilysin-1, MMP7_HUMAN, MMP7

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P09237 MMP7

Gene Names

MMP7, MPSL1, PUMP1

Chain

signal peptide:1-17, propeptide:18-94, chain:95-267

Reference Genes

BioGPS Gene:4316 MMP7

COSMIC (genes):MMP7 MMP7

CTD Gene:4316 MMP7

dbSNP Gene:4316 MMP7

ENSEMBL:ENSG00000137673 MMP7

HGNC:7174 MMP7

KEGG Gene (Homo sapiens):4316 MMP7

Monarch:4316 MMP7

NCBI Gene:4316 MMP7

OMIM:178990 MMP7

UCSC:P09237 MMP7

Reference Transcript

RefSeq:NM_002423.4 MMP7

Other Identifiers

0001400605

11744030_a_at

11744031_at

11756074_a_at

16743647

204259_at

3388674

3388675

3388676

3388677

3388678

3388681

3388682

3388683

3388684

3388685

3388686

4316

668_s_at

7951217

A_23_P52761

GE60350

GO:0000003

GO:0003674

GO:0004175

GO:0004222

GO:0005515

GO:0005575

GO:0005576

GO:0005615

GO:0006508

GO:0006509

GO:0007568

GO:0008150

GO:0008201

GO:0008233

GO:0008237

GO:0008270

GO:0009056

GO:0009986

GO:0016787

GO:0022617

GO:0030198

GO:0030335

GO:0030574

GO:0031012

GO:0031293

GO:0031667

GO:0040011

GO:0043167

GO:0043226

GO:0044849

GO:0046872

GO:0048870

GO:0060135

GO:0070062

GO:0071260

HMNXSV003056491

ILMN_1685403

ILMN_2192072

L22524_s_at

PH_hs_0027041

TC11002228.hg

Participates

as an output of

Autocatalytic activation of MMP7 (Homo sapiens)

Other forms of this molecule

MMP7(18-94) [extracellular region]

MMP7(18-50) [extracellular region]

MMP7(18-267) [extracellular region]

MMP7(51-267) [extracellular region]

MMP7(95-267) [extracellular region]

Inferred To

MMP7(51-94) [extracellular region] (Caenorhabditis elegans)

mmp3 [extracellular region] (Xenopus tropicalis)

Mmp2 [extracellular region] (Drosophila melanogaster)

Mmp7 [extracellular region] (Mus musculus)

Mmp7 [extracellular region] (Rattus norvegicus)

zmp-6 [extracellular region] (Caenorhabditis elegans)

zmp-2 [extracellular region] (Caenorhabditis elegans)

zmp-5 [extracellular region] (Caenorhabditis elegans)

zmp-3 [extracellular region] (Caenorhabditis elegans)

zmp-4 [extracellular region] (Caenorhabditis elegans)

mmp30 [extracellular region] (Danio rerio)

MMP7 [extracellular region] (Bos taurus)

MMP7 [extracellular region] (Canis familiaris)

MMP7 [extracellular region] (Sus scrofa)

Mmp1 [extracellular region] (Drosophila melanogaster)

Homologues of MMP7(51-94) [extracellular region] (Caenorhabditis elegans)

Homologues of MMP7(51-94) [extracellular region] (Drosophila melanogaster)

Cross References

RefSeq

NP_002414.1

ZINC - World Drugs

MMP7_HUMAN

Guide to Pharmacology - Targets

1631

OpenTargets

ENSG00000137673

ZINC - Substances

MMP7_HUMAN

ZINC target

P09237

PRO

P09237

PDB

1MMR, 2MZE, 2MZI, 1MMQ, 2Y6C, 5UE5, 2DDY, 2MZH, 2Y6D, 1MMP, 5UE2

ZINC - Investigational

MMP7_HUMAN

HPA

ENSG00000137673-MMP7

GeneCards

P09237

Ensembl

ENSG00000137673, ENST00000260227, ENSP00000260227

Pharos - Targets

P09237

ZINC - Predictions - Purchasable

MMP7_HUMAN

HMDB Protein

HMDBP02928

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P17931 LGALS3	3	LGALS3 [ficolin-1-rich granule membrane] (R-HSA-6803307) LGALS3 [plasma membrane] (R-HSA-879445) LGALS3 [secretory granule membrane] (R-HSA-6803327)	0.489	5