Reactome | BAZ1B [nucleoplasm]

BAZ1B [nucleoplasm]

Stable Identifier

R-HSA-417153

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Bromodomain adjacent to zinc finger domain protein 1B, BAZ1B_HUMAN, WSTF

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Locations in the PathwayBrowser

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DNA Repair (Homo sapiens)

- DNA Double-Strand Break Repair (Homo sapiens)
  - DNA Double Strand Break Response (Homo sapiens)
    - Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks (Homo sapiens)
      - WICH phosphorylates H2AFX on Y142 (Homo sapiens)
        
        WICH [nucleoplasm] (Homo sapiens)
        
        BAZ1B [nucleoplasm] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q9UIG0 BAZ1B

Gene Names

BAZ1B, WBSC10, WBSCR10, WBSCR9, WSTF

Chain

chain:1-1483

Reference Genes

BioGPS Gene:9031 BAZ1B

COSMIC (genes):BAZ1B BAZ1B

CTD Gene:9031 BAZ1B

dbSNP Gene:9031 BAZ1B

ENSEMBL:ENSG00000009954 BAZ1B

HGNC:961 BAZ1B

KEGG:hsa:9031 BAZ1B

Monarch:9031 BAZ1B

NCBI Gene:9031 BAZ1B

OMIM:605681 BAZ1B

UCSC:Q9UIG0 BAZ1B

Reference Transcript

Other Identifiers

11716387_s_at

11716388_a_at

11716389_a_at

17058460

208445_PM_s_at

208445_s_at

213336_PM_at

213336_at

3056045

3056046

3056047

3056048

3056049

3056050

3056051

3056052

3056053

3056055

3056057

3056060

3056061

3056062

3056063

3056064

3056069

3056071

3056072

3056073

3056075

3056077

3056079

3056081

3056082

3056083

3056084

3056085

3056086

3056087

3056088

3056089

3056090

3056091

3056092

3056094

3056095

3056096

3056097

3056101

3056102

3056103

3056105

32261_at

52586_at

8140037

9031

A_23_P215449

A_33_P3321577

GE82741

GO:0000785

GO:0000793

GO:0003824

GO:0004713

GO:0004715

GO:0005515

GO:0005524

GO:0005634

GO:0005654

GO:0005694

GO:0005721

GO:0005730

GO:0006325

GO:0006338

GO:0006355

GO:0006357

GO:0006974

GO:0008270

GO:0016740

GO:0035173

GO:0042393

GO:0043226

GO:0043596

GO:0043687

GO:0045943

GO:0045944

GO:0045945

GO:0046872

GO:0090535

GO:0110016

GO:0140096

GO:0140801

GO:1905213

HMNXSV003004310

Hs.194688.4.A1_3p_at

Hs.194688.4.A1_3p_x_at

ILMN_1680831

ILMN_1696692

ILMN_1840122

PH_hs_0011501

TC07001499.hg

g12711667_3p_a_at

Participates

as an input of

B-WICH complex binds rDNA promoter (Homo sapiens)

as a component of

Inferred To

Baz1b [nucleoplasm] (Mus musculus)

Baz1b [nucleoplasm] (Rattus norvegicus)

BAZ1B [nucleoplasm] (Bos taurus)

BAZ1B [nucleoplasm] (Canis familiaris)

BAZ1B [nucleoplasm] (Gallus gallus)

BAZ1B [nucleoplasm] (Sus scrofa)

Ghost homologue of BAZ1B [nucleoplasm] (Caenorhabditis elegans)

Cross References

RefSeq

NP_115784.1, XP_016868262.1

Guide to Pharmacology - Targets

2774

ENSEMBL

ENST00000404251, ENSG00000009954, ENSP00000385442, ENST00000339594, ENSP00000342434

OpenTargets

ENSG00000009954

GeneCards

BAZ1B

HPA

ENSG00000009954-BAZ1B

PRO

Q9UIG0

Pharos - Targets

Q9UIG0

GlyGen

Q9UIG0

Orphanet

BAZ1B

PDB

1F62, 5NNF

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O60264 SMARCA5	1	SMARCA5 [nucleoplasm] (R-HSA-417140)	0.81	8
UniProt:P16403 H1-2	1	HIST1H1C [nucleoplasm] (R-HSA-211237)	0.564	2
UniProt:P10412 H1-4	1	HIST1H1E [nucleoplasm] (R-HSA-211251)	0.564	2
UniProt:P28370 SMCA1			0.564	2
UniProt:P12882 MYH1			0.499	3
UniProt:P06748 NPM1	11	NPM1 [cytosol] (R-HSA-3008211) p-S4-NPM1 [cytosol] (R-HSA-6801679) NPM1 [nucleoplasm] (R-HSA-606320) NPM1 [granular component] (R-HSA-9017702) NPM1(1-117)-ALK(1058-1620) fusion [cytosol] (R-HSA-9699834) NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [cytosol] (R-HSA-9699861) NPM1(1-117)-ALK(1068-1620) fusion [cytosol] (R-HSA-9730697) NPM1(1-117)-p-7Y-ALK(1068-1620) fusion [cytosol] (R-HSA-9730703) NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [nucleoplasm] (R-HSA-9725010) polySUMO2,3-K263-NPM1 [nucleoplasm] (R-HSA-4086056) monoSUMO1-K263-NPM1 [nucleoplasm] (R-HSA-4086039)	0.483	2