Reactome | RPS10 [nucleoplasm]

RPS10 [nucleoplasm]

Stable Identifier

R-HSA-6798733

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

40S small ribosomal protein 10, P46783, 40S ribosomal protein S10

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P46783 RPS10

Gene Names

RPS10

Chain

chain:1-165

Reference Genes

BioGPS Gene:6204 RPS10

COSMIC (genes):RPS10 RPS10

CTD Gene:6204 RPS10

dbSNP Gene:6204 RPS10

ENSEMBL:ENSG00000124614 RPS10

ENSEMBL_homo_sapiens_GENE:ENSG00000124614.17 RPS10

HGNC:10383 RPS10

KEGG Gene (Homo sapiens):6204 RPS10

Monarch:6204 RPS10

NCBI Gene:6204 RPS10

OMIM:603632 RPS10

UCSC:P46783 RPS10

Reference Transcript

Other Identifiers

11757758_x_at

11758313_x_at

18670521

18670522

18670523

18670524

200095_PM_x_at

200095_x_at

200817_PM_x_at

200817_x_at

211542_PM_x_at

211542_x_at

2904163

2951151

2951156

2951160

2951161

2951165

2951166

2951167

2951169

2951170

2951171

2951172

2951173

2951174

2997677

3071773

3071779

31568_at

3371638

3371639

3371640

3371642

3834922

6204

7894070

7895324

7895690

7896095

8125835

A_23_P356484

GE580734

GE85992

GO:0002181

GO:0003723

GO:0003735

GO:0005198

GO:0005515

GO:0005634

GO:0005654

GO:0005730

GO:0005737

GO:0005829

GO:0005840

GO:0005925

GO:0006412

GO:0016020

GO:0022626

GO:0022627

GO:0043226

GO:1990904

HMNXSV003017261

Hs.76230.2.S1_3p_x_at

ILMN_1686954

PH_hs_0030063

TC06004130.hg

U14972_at

Participates

as a component of

18SE pre-40S particle [nucleoplasm] (Homo sapiens)

Other forms of this molecule

RPS10 [cytosol]

Inferred To

rps10 [nucleoplasm] (Danio rerio)

rps10 [nucleoplasm] (Dictyostelium discoideum)

rps10 [nucleoplasm] (Xenopus tropicalis)

RPS10B [nucleoplasm] (Saccharomyces cerevisiae)

RPS10 [nucleoplasm] (Bos taurus)

RPS10 [nucleoplasm] (Canis familiaris)

RPS10 [nucleoplasm] (Gallus gallus)

RPS10 [nucleoplasm] (Plasmodium falciparum)

RPS10 [nucleoplasm] (Sus scrofa)

RPS10A [nucleoplasm] (Saccharomyces cerevisiae)

Homologues of RPS10 [nucleoplasm] (Saccharomyces cerevisiae)

rps1002 [nucleoplasm] (Schizosaccharomyces pombe)

Rps10 [nucleoplasm] (Mus musculus)

Rps10 [nucleoplasm] (Rattus norvegicus)

RpS10b [nucleoplasm] (Drosophila melanogaster)

rps-10 [nucleoplasm] (Caenorhabditis elegans)

Cross References

RefSeq

NP_001190174.1, NP_001191020.1, NP_001005.1

OpenTargets

ENSG00000124614

GeneCards

P46783

HPA

ENSG00000124614-RPS10

Ensembl

ENST00000648437, ENST00000467531, ENSP00000494440, ENSP00000494190, ENSP00000497917, ENSG00000124614, ENST00000464218, ENST00000621356, ENSP00000481646

PRO

P46783

Pharos - Targets

P46783

Orphanet

18989

PDB

6ZVH, 8Y0W, 6IP5, 6IP6, 5A2Q, 6ZVJ, 6G5H, 8IFD, 7A09, 6OLF, 7K5I, 6ZLW, 6OLG, 8Y0X, 7TQL, 6OLE, 6ZUO, 7R4X, 6OM7, 8JDM, 6QZP, 6ZP4, 6OLZ, 5LKS, 6ZXH, 6Y0G, 6ZME, 8T4S, 6FEC, 6OLI, 8OZ0, 6ZOJ, 6ZMW, 6G5I, 5FLX, 7QP6, 8JDL, 6ZN5, 6ZXD, 6ZXE, 6Z6M, 8GLP, 6ZOL, 6Z6L, 7QP7, 6Y57, 6ZON, 8G6J, 6ZMO, 5VYC, 6ZXF, 8IFE, 6ZXG, 7XNX, 6ZMI, 7XNY, 4V6X, 6YBS, 5T2C, 6OM0, 6G53, 7QVP, 6Y2L, 6G51, 8G60, 5OA3, 6ZV6, 8PPK, 8PPL, 8G5Y, 6IP8, 4UG0, 8JDJ, 8G61, 5AJ0, 6ZMT, 8JDK, 6XA1, 6ZM7, 6Z6N

Interactors (8)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P63244 RACK1	1	GNB2L1 [cytosol] (R-HSA-5626956)	0.715	4
UniProt:P16104 H2AFX	7	Me2sR4-H2AFX [nucleoplasm] (R-HSA-5218317) H2AFX [nucleoplasm] (R-HSA-56151) p-Y143-H2AFX [nucleoplasm] (R-HSA-5683942) p-S140,Y143-H2AFX [nucleoplasm] (R-HSA-5683953) p-S140-H2AFX [nucleoplasm] (R-HSA-75170) K63PolyUb-K14,K16,p-S140-H2AFX [nucleoplasm] (R-HSA-5682847) H2AFX [extracellular region] (R-HSA-977583)	0.643	4
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.615	14
UniProt:P10636-8 MAPT	3	p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol] (R-HSA-9836400) p-S262,S356,S396-MAPT-8 [cytosol] (R-HSA-9619521) MAPT-8 [cytosol] (R-HSA-9619519)	0.527	7
UniProt:P62249 RPS16	2	RPS16 [nucleoplasm] (R-HSA-6791196) RPS16 [cytosol] (R-HSA-72337)	0.527	3
UniProt:P15880 RPS2	3	RPS2 [nucleoplasm] (R-HSA-6790655) Me2aR-RPS2 [cytosol] (R-HSA-8879138) RPS2 [cytosol] (R-HSA-72347)	0.527	3
UniProt:P06748 NPM1	11	monoSUMO1-K263-NPM1 [nucleoplasm] (R-HSA-4086039) polySUMO2,3-K263-NPM1 [nucleoplasm] (R-HSA-4086056) NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [nucleoplasm] (R-HSA-9725010) NPM1(1-117)-p-7Y-ALK(1068-1620) fusion [cytosol] (R-HSA-9730703) NPM1(1-117)-ALK(1068-1620) fusion [cytosol] (R-HSA-9730697) NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [cytosol] (R-HSA-9699861) NPM1(1-117)-ALK(1058-1620) fusion [cytosol] (R-HSA-9699834) NPM1 [granular component] (R-HSA-9017702) NPM1 [nucleoplasm] (R-HSA-606320) NPM1 [cytosol] (R-HSA-3008211) p-S4-NPM1 [cytosol] (R-HSA-6801679)	0.527	2
UniProt:P0DTC9 N	13	SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [plasma membrane] (R-COV-9729325) SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [nucleolus] (R-COV-9729339) N [plasma membrane] (R-COV-9694356) SUMO1-K62,ADPr-,p-11S,2T,met-R95,177,Ac-K375-N [cytosol] (R-COV-9756489) N [cytosol] (R-COV-9694300) p-S188,206-N [cytosol] (R-COV-9729324) p-8S-N [cytosol] (R-COV-9729335) p-8S,2T-N [cytosol] (R-COV-9729277) p-11S,2T-N [cytosol] (R-COV-9729264) p-11S,2T-metR95,177-N [cytosol] (R-COV-9729308) ADPr-p-11S,2T-metR95,177-N [cytosol] (R-COV-9729275) SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9729341) SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [cytosol] (R-COV-9729340)	0.527	2

Cite Us!