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p-S742 TBX3 [nucleoplasm]
Stable Identifier
R-HSA-9825680
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
T-box transcription factor TBX3, TBX3_HUMAN
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
MITF-M-regulated melanocyte development (Homo sapiens)
Transcriptional and post-translational regulation of MITF-M expression and activity (Homo sapiens)
AKT3 phosphorylates TBX3 (Homo sapiens)
p-S742 TBX3 [nucleoplasm] (Homo sapiens)
SNAI2 and TBX3 repress CDH1 gene expression during melanocyte development (Homo sapiens)
p-S742 TBX3 [nucleoplasm] (Homo sapiens)
p-S742 TBX3:CDH1 gene [nucleoplasm] (Homo sapiens)
p-S742 TBX3 [nucleoplasm] (Homo sapiens)
TBX3-dependent ID1 gene expression (Homo sapiens)
p-S742 TBX3 [nucleoplasm] (Homo sapiens)
p-S742 TBX3:ID1 gene [nucleoplasm] (Homo sapiens)
p-S742 TBX3 [nucleoplasm] (Homo sapiens)
p-S742 TBX3 binds CDH1 promoter (Homo sapiens)
p-S742 TBX3 [nucleoplasm] (Homo sapiens)
p-S742 TBX3:CDH1 gene [nucleoplasm] (Homo sapiens)
p-S742 TBX3 [nucleoplasm] (Homo sapiens)
p-S742 TBX3 binds ID1 promoter (Homo sapiens)
p-S742 TBX3 [nucleoplasm] (Homo sapiens)
p-S742 TBX3:ID1 gene [nucleoplasm] (Homo sapiens)
p-S742 TBX3 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:O15119 TBX3
Gene Names
TBX3
Chain
chain:1-743
Reference Genes
BioGPS Gene:6926 TBX3
COSMIC (genes):TBX3 TBX3
CTD Gene:6926 TBX3
dbSNP Gene:6926 TBX3
ENSEMBL:ENSG00000135111 TBX3
HGNC:11602 TBX3
Monarch:6926 TBX3
NCBI Gene:6926 TBX3
OMIM:601621 TBX3
UCSC:O15119 TBX3
Reference Transcript
RefSeq:NM_016569.3 TBX3
RefSeq:NM_005996.3 TBX3
Other Identifiers
11721428_a_at
11721429_a_at
11740097_a_at
11746985_s_at
11757916_s_at
11760724_at
16770685
219682_PM_s_at
219682_s_at
222917_PM_s_at
222917_s_at
225544_PM_at
225544_at
229576_PM_s_at
229576_s_at
3472758
3472759
3472760
3472761
3472762
3472763
3472764
3472767
3472768
3472771
3472772
3472773
3472774
3472775
3472776
3472777
3472780
3472781
3472782
3472783
3472784
49375_at
6926
78725_at
7966690
A_23_P13772
A_23_P383819
GE62199
GE81584
GO:0000122
GO:0000785
GO:0000978
GO:0000981
GO:0001227
GO:0001228
GO:0001501
GO:0001568
GO:0001701
GO:0001708
GO:0001947
GO:0003007
GO:0003012
GO:0003151
GO:0003167
GO:0003272
GO:0003677
GO:0003700
GO:0005515
GO:0005634
GO:0005654
GO:0005929
GO:0006351
GO:0006355
GO:0006357
GO:0008284
GO:0008595
GO:0009887
GO:0010159
GO:0019827
GO:0021761
GO:0022414
GO:0030154
GO:0030539
GO:0030540
GO:0030857
GO:0030879
GO:0031647
GO:0032275
GO:0035050
GO:0035108
GO:0035115
GO:0035116
GO:0035136
GO:0036302
GO:0042127
GO:0042472
GO:0042733
GO:0043066
GO:0043226
GO:0043565
GO:0045662
GO:0045787
GO:0045892
GO:0045893
GO:0045944
GO:0046884
GO:0048332
GO:0048752
GO:0048856
GO:0051145
GO:0055007
GO:0060021
GO:0060317
GO:0060412
GO:0060444
GO:0060596
GO:0060923
GO:0060931
GO:0061017
GO:0061629
GO:0061635
GO:0072089
GO:0072105
GO:0090398
GO:0140110
GO:1905072
GO:1905222
GO:1990837
GO:2000137
GO:2000648
GO:2000737
HMNXSV003040918
Hs.267182.0.S2_3p_at
Hs.267182.1.S1_3p_s_at
Hs.332150.0.A1_3p_s_at
ILMN_1701393
ILMN_1713449
PH_hs_0024082
TC12002000.hg
TC12003096.hg
g7706728_3p_s_at
Participates
as an input of
p-S742 TBX3 binds ID1 promoter (Homo sapiens)
p-S742 TBX3 binds CDH1 promoter (Homo sapiens)
as a component of
p-S742 TBX3:ID1 gene [nucleoplasm] (Homo sapiens)
p-S742 TBX3:CDH1 gene [nucleoplasm] (Homo sapiens)
as an output of
AKT3 phosphorylates TBX3 (Homo sapiens)
Other forms of this molecule
TBX3 [nucleoplasm]
Inferred To
phospho-Tbx3 [nucleoplasm]
(Mus musculus)
phospho-Tbx3 [nucleoplasm]
(Rattus norvegicus)
phospho-tbx-2 [nucleoplasm]
(Caenorhabditis elegans)
phospho-tbx3 [nucleoplasm]
(Xenopus tropicalis)
phospho-TBX3 [nucleoplasm]
(Bos taurus)
phospho-TBX3 [nucleoplasm]
(Canis familiaris)
phospho-TBX3 [nucleoplasm]
(Gallus gallus)
phospho-TBX3 [nucleoplasm]
(Sus scrofa)
phospho-bi [nucleoplasm]
(Drosophila melanogaster)
Modified Residues
Name
O-phospho-L-serine at 742
Coordinate
742
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
ENSEMBL
ENST00000257566
,
ENST00000349155
,
ENSP00000257566
,
ENSP00000257567
OpenTargets
ENSG00000135111
HPA
ENSG00000135111-TBX3
PRO
O15119
Pharos - Targets
O15119
GlyGen
O15119
Orphanet
TBX3
PDB
1H6F
Interactors (7)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q8N4W3 Q8N4W3
0.556
3
IntAct:EBI-22616457 CCSB ORF ID
0.556
3
UniProt:P86480 PR20D
0.556
3
UniProt:P35219 CAH8
0.556
3
UniProt:Q6NVU6 UFSP1
0.556
3
UniProt:Q99471 PFDN5
1
PFDN5 [cytosol]
(R-HSA-379548)
0.556
3
UniProt:Q08117 TLE5
1
AES [nucleoplasm]
(R-HSA-4648963)
0.556
3
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