Reactome | IFITM3 [plasma membrane]

IFITM3 [plasma membrane]

Stable Identifier

R-HSA-1015688

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Interferon-induced transmembrane protein 3, IFM3_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q01628 IFITM3

Gene Names

IFITM3

Chain

chain:1-133

Reference Genes

BioGPS Gene:10410 IFITM3

COSMIC (genes):IFITM3 IFITM3

CTD Gene:10410 IFITM3

dbSNP Gene:10410 IFITM3

ENSEMBL:ENSG00000142089.17 IFITM3

HGNC:5414 IFITM3

KEGG Gene (Homo sapiens):10410 IFITM3

Monarch:10410 IFITM3

NCBI Gene:10410 IFITM3

OMIM:605579 IFITM3

UCSC:Q01628 IFITM3

Reference Transcript

RefSeq:NM_021034.2 IFITM3

Other Identifiers

10410

11715239_x_at

212203_PM_x_at

212203_x_at

3315670

3315674

3357843

3357844

3357845

3357846

3357851

3357852

41745_at

676_g_at

7945371

A_23_P87545

GE82581

GO:0002376

GO:0005515

GO:0005737

GO:0005764

GO:0005765

GO:0005768

GO:0005773

GO:0005886

GO:0006955

GO:0009615

GO:0016020

GO:0016021

GO:0023052

GO:0031410

GO:0031901

GO:0031902

GO:0032897

GO:0032991

GO:0034341

GO:0035455

GO:0035456

GO:0043226

GO:0045071

GO:0045087

GO:0046597

GO:0048471

GO:0051607

GO:0060337

GO:0098542

HMNXSV003042131

Hs.182241.2.S1_3p_x_at

ILMN_1805750

TC11001230.hg

X57351_s_at

Participates

as an output of

Expression of IFN-induced genes (Homo sapiens)

Cross References

RefSeq

NP_066362.2

OpenTargets

ENSG00000142089

GeneCards

Q01628

HPA

ENSG00000142089-IFITM3

Ensembl

ENSP00000382707, ENST00000399808, ENSG00000142089

PRO

Q01628

Pharos - Targets

Q01628

Interactors (24)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q6UWN5 LYPD5	2	cleaved GPI-LYPD5 [extracellular region] (R-HSA-8941140) GPI-LYPD5 [plasma membrane] (R-HSA-8940779)	0.556	3
UniProt:P43628 KIR2DL3	1	KIR2DL3 [plasma membrane] (R-HSA-3006532)	0.556	3
UniProt:Q9Y282 ERGI3			0.556	3
UniProt:O60669 SLC16A7	1	SLC16A7 [plasma membrane] (R-HSA-373955)	0.556	3
UniProt:Q96HJ5 MS4A3	2	MS4A3 [plasma membrane] (R-HSA-6806321) MS4A3 [specific granule membrane] (R-HSA-6799514)	0.556	3
UniProt:Q12908 SLC10A2	1	SLC10A2 [plasma membrane] (R-HSA-194173)	0.556	3
UniProt:Q96KR6 F210B			0.556	3
UniProt:P60201-2 PLP1			0.556	3
UniProt:O95870 ABHGA			0.556	3
UniProt:Q9H6H4 REEP4			0.556	3
UniProt:Q9NXB9 ELOVL2	1	ELOVL2 [endoplasmic reticulum membrane] (R-HSA-548677)	0.556	3
UniProt:P19397 CD53	3	CD53 [tertiary granule membrane] (R-HSA-6804799) CD53 [plasma membrane] (R-HSA-6804817) CD53 [specific granule membrane] (R-HSA-6804793)	0.556	3
UniProt:Q86VR2 RETR3			0.556	3
UniProt:P35372-10 OPRM1			0.556	3
UniProt:Q13520 AQP6	1	AQP6 [transport vesicle membrane] (R-HSA-431741)	0.556	3
UniProt:Q9NUH8 TM14B			0.556	3
UniProt:Q9Y680 FKBP7			0.556	3
UniProt:Q9NZD1 GPC5D			0.556	3
UniProt:Q14973 SLC10A1	1	SLC10A1 [plasma membrane] (R-HSA-194116)	0.556	3
UniProt:O15552 FFAR2	1	FFAR2 [plasma membrane] (R-HSA-443944)	0.556	3
UniProt:O95470 SGPL1	1	PXLP-SGPL1 [endoplasmic reticulum membrane] (R-HSA-428661)	0.556	3
UniProt:Q8N661 TMEM86B	1	TMEM86B [endoplasmic reticulum membrane] (R-HSA-8874443)	0.556	3
UniProt:O95415 BRI3	2	BRI3 [plasma membrane] (R-HSA-6806260) BRI3 [azurophil granule membrane] (R-HSA-6799127)	0.543	6
UniProt:P43490 NAMPT	1	NAMPT [cytosol] (R-HSA-197188)	0.508	3

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