Reactome | RNF152 [lysosomal membrane]

RNF152 [lysosomal membrane]

Stable Identifier

R-HSA-8938832

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

lysosomal membrane

Synonyms

fullName evidence="5"E3 ubiquitin-protein ligase RNF152 ecNumber evidence="4"6.3.2.-/ecNumber, RN152_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q8N8N0 RNF152

Gene Names

RNF152

Chain

chain:1-203

Reference Genes

BioGPS Gene:220441 RNF152

COSMIC (genes):RNF152 RNF152

CTD Gene:220441 RNF152

dbSNP Gene:220441 RNF152

ENSEMBL:ENSG00000176641 RNF152

HGNC:26811 RNF152

KEGG Gene (Homo sapiens):220441 RNF152

Monarch:220441 RNF152

NCBI Gene:220441 RNF152

OMIM:616512 RNF152

UCSC:Q8N8N0 RNF152

Reference Transcript

Other Identifiers

11732768_at

11732769_at

1553721_at

1553722_s_at

16855629

220441

3810992

3810993

3810994

3810995

3811001

3811002

3811003

3811004

3811005

3811006

3811007

3811008

3811018

3811019

62263_at

8023598

A_32_P4199

A_32_P456209

GE545275

GE868794

GO:0000209

GO:0003674

GO:0004842

GO:0005515

GO:0005575

GO:0005622

GO:0005737

GO:0005764

GO:0005765

GO:0005773

GO:0006464

GO:0006914

GO:0006915

GO:0006950

GO:0007165

GO:0008150

GO:0008219

GO:0009056

GO:0010508

GO:0016020

GO:0016021

GO:0016567

GO:0016740

GO:0019899

GO:0031267

GO:0031301

GO:0034198

GO:0043167

GO:0043226

GO:0046872

GO:0061630

GO:0070534

GO:0070936

GO:1904262

HMNXSV003019209

HMNXSV003027696

Hs2.243623.1.A1_3p_at

Hs2.243623.1.A1_3p_s_at

ILMN_2071826

PH_hs_0012995

TC18000551.hg

TC18000947.hg

Participates

as an output of

RNF152 polyubiquitinates RRAGA (Homo sapiens)

as a component of

RNF152:RRAGA:GDP:Ub:UBE2N [lysosomal membrane] (Homo sapiens)

as an input of

RNF152 binds RRAGA:GDP and Ubiquitin:UBE2D3 (Homo sapiens)

Inferred To

Rnf152 [lysosomal membrane] (Mus musculus)

Rnf152 [lysosomal membrane] (Rattus norvegicus)

RNF152 [lysosomal membrane] (Bos taurus)

RNF152 [lysosomal membrane] (Caenorhabditis elegans)

RNF152 [lysosomal membrane] (Canis familiaris)

RNF152 [lysosomal membrane] (Dictyostelium discoideum)

RNF152 [lysosomal membrane] (Gallus gallus)

RNF152 [lysosomal membrane] (Sus scrofa)

Ghost homologue of RNF152 [lysosomal membrane] (Drosophila melanogaster)

Ghost homologue of RNF152 [lysosomal membrane] (Saccharomyces cerevisiae)

Ghost homologue of RNF152 [lysosomal membrane] (Schizosaccharomyces pombe)

rnf152 [lysosomal membrane] (Danio rerio)

rnf152 [lysosomal membrane] (Xenopus tropicalis)

Cross References

RefSeq

XP_005266707.1, XP_011524181.1, XP_011524180.1, XP_016881101.1, NP_775828.1, XP_005266709.1, XP_016881102.1

OpenTargets

ENSG00000176641

HPA

ENSG00000176641-RNF152

GeneCards

Q8N8N0

Ensembl

ENST00000312828, ENSG00000176641, ENSP00000316628

PRO

Q8N8N0

Pharos - Targets

Q8N8N0

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P43628 KIR2DL3	1	KIR2DL3 [plasma membrane] (R-HSA-3006532)	0.556	3
UniProt:O95859 TSN12			0.556	3
UniProt:Q99732 LITAF			0.556	3
UniProt:Q15125 EBP	1	EBP [endoplasmic reticulum membrane] (R-HSA-195697)	0.556	3
UniProt:P48165 GJA8	1	GJA8 [endoplasmic reticulum membrane] (R-HSA-190702)	0.556	3

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