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P4HA3 [endoplasmic reticulum lumen]
Stable Identifier
R-HSA-2980915
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum lumen
Synonyms
Prolyl 4-hydroxylase subunit alpha-3, P4HA3_HUMAN
Locations in the PathwayBrowser
Expand all
Extracellular matrix organization (Homo sapiens)
Collagen formation (Homo sapiens)
Collagen biosynthesis and modifying enzymes (Homo sapiens)
Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines (Homo sapiens)
Prolyl 4-hydroxylases [endoplasmic reticulum lumen] (Homo sapiens)
Prolyl 4-hydroxylase alpha subunits [endoplasmic reticulum lumen] (Homo sapiens)
P4HA3 [endoplasmic reticulum lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q7Z4N8 P4HA3
Gene Names
P4HA3, UNQ711/PRO1374
Chain
signal peptide:1-19, chain:20-544
Reference Genes
BioGPS Gene:283208 P4HA3
COSMIC (genes):P4HA3 P4HA3
CTD Gene:283208 P4HA3
dbSNP Gene:283208 P4HA3
ENSEMBL:ENSG00000149380 P4HA3
HGNC:30135 P4HA3
Monarch:283208 P4HA3
NCBI Gene:283208 P4HA3
OMIM:608987 P4HA3
UCSC:Q7Z4N8 P4HA3
Reference Transcript
RefSeq:NM_182904.4 P4HA3
RefSeq:NM_001288748.1 P4HA3
Other Identifiers
11725272_a_at
1560715_3p_at
1560715_PM_at
1560715_at
16742058
228703_PM_at
228703_at
283208
3381880
3381881
3381882
3381883
3381887
3381888
3381889
3381893
3381894
3381895
3381896
3381897
3381898
3381900
3381902
3381903
3381904
3381905
3381906
3381908
3381909
3381910
3381917
3381918
3381920
3381921
3381922
3381923
3381924
7950374
84983_at
A_23_P127957
A_24_P290286
GO:0003824
GO:0004656
GO:0005506
GO:0005515
GO:0005783
GO:0005788
GO:0016491
GO:0016705
GO:0031418
GO:0043226
GO:0046872
GO:0051213
GO:0140096
HMNXSV003037256
HMNXSV003046609
HMNXSV003058331
Hs.179891.0.A1_3p_at
Hs2.435828.1.S1_3p_at
Hs2.435828.1.S1_3p_x_at
ILMN_1690121
PH_hs_0020972
PH_hs_0036019
TC11002078.hg
TC11002079.hg
Participates
as a member of
Prolyl 4-hydroxylase alpha subunits [endoplasmic reticulum lumen] (Homo sapiens)
Inferred To
p4ha3 [endoplasmic reticulum lumen]
(Xenopus tropicalis)
Homologues of P4HA3 [endoplasmic reticulum lumen]
(Caenorhabditis elegans)
phy-3 [endoplasmic reticulum lumen]
(Caenorhabditis elegans)
phy-4 [endoplasmic reticulum lumen]
(Caenorhabditis elegans)
P4HA3 [endoplasmic reticulum lumen]
(Bos taurus)
P4HA3 [endoplasmic reticulum lumen]
(Caenorhabditis elegans)
P4HA3 [endoplasmic reticulum lumen]
(Canis familiaris)
P4HA3 [endoplasmic reticulum lumen]
(Gallus gallus)
P4HA3 [endoplasmic reticulum lumen]
(Mus musculus)
P4HA3 [endoplasmic reticulum lumen]
(Rattus norvegicus)
P4HA3 [endoplasmic reticulum lumen]
(Sus scrofa)
Cross References
ENSEMBL
ENSP00000332170
,
ENST00000331597
,
ENSP00000401749
,
ENST00000427714
,
ENST00000524388
,
ENSP00000433860
OpenTargets
ENSG00000149380
HPA
ENSG00000149380-P4HA3
PRO
Q7Z4N8
Pharos - Targets
Q7Z4N8
GlyGen
Q7Z4N8
HMDB Protein
HMDBP09111
Interactors (14)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q5D1E8 ZC3H12A
1
ZC3H12A [nucleoplasm]
(R-HSA-9774235)
0.718
6
UniProt:O14964 HGS
2
HGS [cytosol]
(R-HSA-182954)
HGS [phagocytic vesicle lumen]
(R-HSA-9635660)
0.718
6
UniProt:O14734 ACOT8
2
ACOT8 [cytosol]
(R-HSA-9033134)
ACOT8 [peroxisomal matrix]
(R-HSA-193426)
0.556
3
UniProt:Q9NSG2 FIRRM
4
p-S43,S744-FIRRM [cytosol]
(R-HSA-9853437)
p-S43-FIRRM [cytosol]
(R-HSA-9851990)
FIRRM [cytosol]
(R-HSA-9851948)
FIRRM [nucleoplasm]
(R-HSA-9853387)
0.556
3
UniProt:Q9UJ68 MSRA
1
MSRA [cytosol]
(R-HSA-5676904)
0.556
3
UniProt:Q96EV8 DTNBP1
1
DTNBP1 [cytosol]
(R-HSA-429819)
0.556
3
UniProt:O95429 BAG4
3
BAG4 [cytosol]
(R-HSA-5212670)
BAG4(1-126)-p-8Y-FGFR1(208-822) fusion [plasma membrane]
(R-HSA-8853156)
BAG4(1-126)-FGFR1(208-822) fusion [plasma membrane]
(R-HSA-8853157)
0.556
3
UniProt:Q9NSA3 CTNNBIP1
1
CTNNBIP1 [nucleoplasm]
(R-HSA-3772388)
0.556
3
UniProt:P28070 PSMB4
4
PSMB4 [cytosol]
(R-HSA-68750)
PSMB4 [nucleoplasm]
(R-HSA-174343)
pro-PSMB4 [cytosol]
(R-HSA-9908138)
PSMB4(1-45) [cytosol]
(R-HSA-9908122)
0.556
3
UniProt:O95619 YEATS4
1
YEATS4 [nucleoplasm]
(R-HSA-3322940)
0.527
2
UniProt:Q14493 SLBP
2
SLBP [nucleoplasm]
(R-HSA-64547)
SLBP [cytosol]
(R-HSA-141613)
0.527
2
UniProt:P11021 HSPA5
6
HSPA5 [lumenal side of endoplasmic reticulum membrane]
(R-HSA-985498)
HSPA5 [nucleoplasm]
(R-HSA-5252042)
HSPA5 [cytosol]
(R-HSA-5252115)
HSPA5 [endoplasmic reticulum membrane]
(R-HSA-351315)
HSPA5 [endoplasmic reticulum lumen]
(R-HSA-387190)
HSPA5 [extracellular region]
(R-HSA-351322)
0.527
2
UniProt:P07237 P4HB
3
P4HB [endoplasmic reticulum lumen]
(R-HSA-174692)
p-P4HB [endoplasmic reticulum lumen]
(R-HSA-8956902)
HC53,56-P4HB [endoplasmic reticulum lumen]
(R-HSA-3341287)
0.527
2
UniProt:Q9UMN6 KMT2B
5
KMT2B [cytosol]
(R-HSA-9818624)
KMT2B(2-2062) [cytosol]
(R-HSA-9818621)
KMT2B(2063-2715) [cytosol]
(R-HSA-9818626)
KMT2B(2063-2715) [nucleoplasm]
(R-HSA-9818623)
KMT2B(2-2062) [nucleoplasm]
(R-HSA-9818620)
0.527
2
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