HGS

Stable Identifier
R-HSA-182954
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
Hepatocyte growth factor-regulated tyrosine kinase substrate
Locations in the PathwayBrowser
External Reference Information
External Reference
Gene Names
HGS, HRS
Chain
chain:1-777
Reference Transcript
Other Identifiers
0005130048
11748740_x_at
11751648_a_at
16838855
210428_3p_s_at
210428_s_at
2D3G
33887_at
3738141
3738142
3738147
3738150
3738152
3738153
3738157
3738158
3738161
3738164
3738166
3738167
3738171
3738173
3738174
3738176
3738177
3738182
3738185
3738186
3738188
3738189
3738190
3738195
3738196
3738198
3738202
3738203
3738204
3F1I
3OBQ
3ZYQ
4872
4AVX
7728
8010638
9146
A0A0S2Z4R4
A_23_P61230
A_23_P72627
A_24_P125993
AAC51929
AAF82361
AAH03565
AAP88756
AF260566
ALQ33924
BAA23366
BC003565
BT009754
CCDS11784
CH471099
D84064
EAW89675
ENSG00000185359
ENSP00000331201
ENST00000329138
EntrezGene:9146
g9022388_3p_a_at
g9022388_3p_x_at
GE59171
GO:0003674
GO:0005515
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005623
GO:0005737
GO:0005764
GO:0005768
GO:0005769
GO:0005773
GO:0005829
GO:0006464
GO:0006605
GO:0006622
GO:0006810
GO:0006886
GO:0006914
GO:0007034
GO:0007165
GO:0008150
GO:0008283
GO:0008285
GO:0009056
GO:0010324
GO:0010628
GO:0010642
GO:0015031
GO:0016020
GO:0016192
GO:0016197
GO:0016236
GO:0016301
GO:0016310
GO:0016525
GO:0016579
GO:0019899
GO:0019904
GO:0022607
GO:0030948
GO:0031410
GO:0031901
GO:0032585
GO:0033565
GO:0036258
GO:0042059
GO:0042176
GO:0043167
GO:0043226
GO:0043231
GO:0043234
GO:0043405
GO:0044389
GO:0046426
GO:0046872
GO:0048646
GO:0048856
GO:0061024
GO:0070062
GO:0072657
GO:1903543
HGNC:4897
HGS
HGS-201
HPA004872
HPA007728
ILMN_1715994
IPR000306
IPR002014
IPR003903
IPR008942
IPR011011
IPR013083
IPR017073
IPR017455
IPR024641
KU178466
MIM:604375
NM_004712
NP_004703
PF00790
PF01363
PF12210
PH_hs_0025066
SM00064
SM00288
TC17000935.hg
U43895
uc002kbg.4
UPI000004493D
XM_011525463
XM_017025297
XM_017025298
XP_011523765
XP_016880786
XP_016880787
Participant Of
Inferred To
Cross References
RefSeq
GeneCards
DOCK Blaster
PRO
PDB
Interactors (249)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:O95751 LDOC1      0.841 9
 UniProt:P0CG48 UBC  316 0.84 8
 UniProt:Q96M63 CC114      0.795 8
 UniProt:Q13287 NMI      0.764 9
 UniProt:P05783 KRT18  1 0.764 6
 UniProt:Q15038 DAZP2      0.764 6
 UniProt:Q8NDC0 MISSL      0.718 6
 UniProt:Q6A162 KRT40  1 0.718 6
 UniProt:Q99732 LITAF      0.718 7
 UniProt:P02538 KRT6A  1 0.718 6
 UniProt:Q8WYH8 ING5  1 0.696 5
 UniProt:P13646 KRT13  1 0.696 5
 UniProt:Q08117-2 AES      0.696 5
 UniProt:Q15323 KRT31  1 0.696 5
 UniProt:P33240 CSTF2  1 0.696 5
 UniProt:O76015 KRT38  1 0.696 5
 UniProt:Q9H9H4 VPS37B  1 0.696 5
 UniProt:Q7Z3B4 NUP54  1 0.696 5
 UniProt:Q14525 KRT33B  1 0.696 5
 UniProt:Q96HT8 MR1L1      0.696 5
 UniProt:Q86WT6-2 TRIM69      0.696 7
 UniProt:Q92567-2 FAM168A      0.696 5
 UniProt:Q9Y577 TRIM17  1 0.696 5
 UniProt:O43186 CRX      0.696 5
 UniProt:Q969V4 TEKT1      0.696 5
 UniProt:Q9BUZ4 TRAF4      0.696 5
 UniProt:P19012 KRT15  1 0.696 5
 UniProt:Q9Y5V3 MAGED1  1 0.696 5
 UniProt:Q7Z4N8 P4HA3  1 0.696 5
 UniProt:Q96MT8-3 CEP63      0.696 5
 UniProt:O14777 NDC80  1 0.696 5
 UniProt:Q01850 CDR2      0.696 5
 UniProt:A9UHW6-2 MIF4GD      0.696 5
 UniProt:Q7Z3K3 POGZ      0.696 5
 UniProt:Q92783-1 STAM      0.678 5
 UniProt:A9UHW6 MI4GD      0.666 4
 UniProt:Q9UPT5 EXOC7  2 0.666 4
 UniProt:O43513 MED7  1 0.666 4
 UniProt:Q8N6Y0 USBP1      0.666 4
 UniProt:Q99816 TSG101  1 0.635 4
 UniProt:Q96LR2 LURA1      0.621 3
 UniProt:O75478 TADA2A  1 0.621 3
 UniProt:Q53EZ4 CEP55      0.621 4
 UniProt:P08727 KRT19  1 0.621 3
 1-phosphatidyl-1D-myo-inositol 3-phosphate [ChEBI:17283]  6 0.602 4
 UniProt:Q92783 STAM  1 0.573 2
 UniProt:Q99816-1 TSG101      0.558 2
 UniProt:P62990 UBIQ      0.558 2
 UniProt:Q9UBV8 PEF1      0.556 3
 UniProt:P32502  1 0.556 3
 UniProt:Q96MW5 COG8  2 0.556 3
 UniProt:A0A0S2Z4A7 A0A0S2Z4A7      0.556 3
 UniProt:Q9P2B4 CT2NL      0.556 3
 UniProt:Q6P1W5 CA094      0.556 3
 UniProt:Q8N1B4 VPS52  1 0.556 3
 UniProt:A5D8V6 VPS37C  1 0.556 3
 UniProt:P40460 NDC80      0.556 3
 IntAct:EBI-16435328 CCSB ORF ID      0.556 3
 UniProt:O75177-5 SS18L1      0.556 3
 UniProt:Q9H0L4 CSTF2T  1 0.556 3
 UniProt:O75934 BCAS2  1 0.556 3
 UniProt:Q96LI6 HSFY1      0.556 3
 IntAct:EBI-16429386 CCSB ORF ID      0.556 3
 UniProt:Q8HWS3 RFX6  1 0.556 3
 UniProt:Q96AA8 JKIP2      0.556 3
 UniProt:O94868-3 FCHSD2      0.556 3
 UniProt:O75558 STX11      0.556 3
 UniProt:P53365 ARFIP2  1 0.556 3
 UniProt:I6L9F6 I6L9F6      0.556 3
 UniProt:P63165 SUMO1  154 0.556 3
 UniProt:O15481 MAGB4      0.556 3
 UniProt:Q8IW40 CC103      0.556 3
 UniProt:Q96HW7-2 INTS4      0.556 3
 UniProt:Q9UNH6 SNX7      0.556 3
 UniProt:Q9NYB9 ABI2  2 0.556 3
 UniProt:O13566 YP123      0.556 3
 UniProt:Q6PEX3 KRTAP26-1  1 0.556 3
 UniProt:Q96HW7 INTS4  1 0.556 3
 UniProt:Q08379 GOLGA2  3 0.556 3
 UniProt:Q8IYX8-2 CEP57L1      0.556 3
 UniProt:O75478-2 TADA2A      0.556 3
 UniProt:O13539 THP2      0.556 3
 UniProt:O00471 EXOC5  2 0.556 3
 UniProt:Q8NDV7-4 TNRC6A      0.488 2
 UniProt:Q92764 KRT35  1 0.488 2
 UniProt:P0C853 BAAS2      0.488 2
 UniProt:Q6ICM1 Q6ICM1      0.488 2
 UniProt:Q12824-2 SMARCB1      0.488 2
 UniProt:O76013-2 KRT36      0.488 2
 UniProt:O15544 GR6      0.488 2
 UniProt:A8MV65-2 VGLL3      0.488 2
 UniProt:Q96CS2 HAUS1  1 0.488 2
 UniProt:Q9ULX6 AKP8L      0.488 2
 UniProt:P37198 NUP62  1 0.488 2
 UniProt:Q9UDY6-2 TRIM10      0.488 2
 UniProt:Q8WXK4-2 Q8WXK42      0.488 2
 UniProt:Q3KP44 ANR55      0.488 2
 UniProt:P35250-2 RFC2      0.488 2
 UniProt:Q9Y5P8 PPP2R3B  1 0.488 2
 UniProt:P61968 LMO4      0.488 2
 IntAct:EBI-10696557 ARAP3      0.488 2
 UniProt:Q6P2S7-3 TTC41P      0.488 2
 UniProt:Q2NKJ9 Q2NKJ9      0.488 2
 UniProt:Q14847-2 LASP1      0.488 2
 UniProt:P0C870 JMJD7      0.488 2
 UniProt:Q8TEX9 IPO4      0.488 2
 UniProt:P02533 KRT14  1 0.488 2
 UniProt:D3DX41 D3DX41      0.488 2
 UniProt:Q8WWB3 DYDC1      0.488 2
 UniProt:Q15654 TRIP6      0.488 2
 UniProt:Q2KHM9 MOONR      0.488 2
 UniProt:O43474 KLF4  1 0.488 2
 UniProt:A1E959 ODAM  1 0.488 2
 UniProt:O00167-2 EYA2      0.488 2
 UniProt:Q5SSQ6-2 SAPCD1      0.488 2
 UniProt:O76011 KRT34  1 0.488 2
 UniProt:P14079 TAX      0.488 4
 UniProt:P35555 FBN1  7 0.488 2
 UniProt:P0C7W6 CC172      0.488 2
 UniProt:P36406 TRI23      0.488 2
 UniProt:Q71SY5 MED25  1 0.488 2
 UniProt:Q13952-2 NFYC      0.488 2
 UniProt:Q9NZ72 STMN3      0.488 2
 UniProt:Q5HY92 FIGN      0.488 2
 UniProt:Q06710 PAX8      0.488 2
 UniProt:O95678 KRT75  1 0.488 2
 UniProt:O76014 KRT37  1 0.488 2
 UniProt:O60806 TBX19      0.488 2
 UniProt:Q86V38 Q86V38      0.488 2
 UniProt:O43482 OIP5  1 0.488 2
 UniProt:Q16633 OBF1      0.488 2
 UniProt:Q9UHD9 UBQLN2  1 0.488 4
 UniProt:Q8N7C3 TRIMM      0.488 2
 UniProt:Q16609 LPAL2      0.488 2
 UniProt:Q96LB3-2 IFT74      0.488 2
 UniProt:M0R160 M0R160      0.488 2
 UniProt:A0A1B0GWI1 A0A1B0GWI1      0.488 2
 IntAct:EBI-12904486 DAAM2      0.488 2
 UniProt:P08779 KRT16  1 0.488 2
 UniProt:Q3LI72 KRTAP19-5  1 0.488 2
 UniProt:Q9NU39 FX4L1      0.488 2
 UniProt:Q9NPJ6 MED4  1 0.488 2
 UniProt:Q2M2I5 KRT24  1 0.488 2
 UniProt:Q9NQL9 DMRT3      0.488 2
 UniProt:Q6AI39 BICRL      0.488 2
 UniProt:Q96HR3 MED30  1 0.488 2
 UniProt:P51178 PLCD1  1 0.488 2
 UniProt:P03410 TAX      0.488 4
 IntAct:EBI-17461764 CSNK1G2AS1      0.488 2
 UniProt:Q9H410 DSN1  3 0.488 2
 UniProt:Q8NAE3 CA180      0.488 2
 UniProt:Q99687-3 Q996873      0.488 2
 UniProt:Q86VI1 EX3L1      0.488 2
 UniProt:Q3SXR2 CC036      0.488 2
 UniProt:Q8N1F1 C1AS1      0.488 2
 UniProt:Q92783-2 STAM      0.488 2
 UniProt:Q86UW9 DTX2  1 0.488 2
 UniProt:O43790 KRT86  1 0.488 2
 UniProt:Q9HBM1 SPC25  1 0.488 2
 UniProt:Q8N0U4 F185A      0.488 2
 UniProt:Q2TAP0 GOG7B      0.488 2
 UniProt:G2XKQ0 G2XKQ0      0.488 2
 IntAct:EBI-17199802 AC099791.1      0.488 2
 UniProt:Q7Z6I5 SPT12      0.488 2
 UniProt:Q6A163 KRT39  1 0.488 2
 UniProt:Q9UJW9 SRTD3      0.488 2
 UniProt:Q8IYU4 UBQLN      0.488 2
 UniProt:P28070 PSMB4  2 0.488 2
 UniProt:P40199 CEACAM6  2 0.488 2
 UniProt:P18825 ADRA2C  1 0.488 2
 UniProt:Q96GS4 BORC6      0.488 2
 UniProt:Q8IV33 K0825      0.488 2
 UniProt:Q9NSB4 KRT82  1 0.488 2
 UniProt:Q96LM9 CT173      0.488 2
 UniProt:Q2I0M5 RSPO4  1 0.488 2
 UniProt:P12035 KRT3  1 0.488 2
 UniProt:Q7Z3Y8 KRT27  1 0.488 2
 UniProt:Q7Z3Y9 KRT26  1 0.488 2
 UniProt:Q7Z5V6-2 PPP1R32      0.488 4
 UniProt:O60504 SORBS3  1 0.488 2
 UniProt:Q8N6F8 MET27      0.488 2
 UniProt:O15496 PLA2G10  1 0.488 2
 IntAct:EBI-12834768 GUSBP2      0.488 2
 UniProt:Q9H6L4 ARMC7      0.488 2
 UniProt:P78317 RNF4  2 0.488 2
 UniProt:Q5T6F2 UBAP2      0.488 2
 UniProt:Q7Z3Z0 KRT25  1 0.488 2
 UniProt:Q86UX6 ST32C      0.488 2
 UniProt:P85299-2 PRR5      0.488 2
 UniProt:A5D917 A5D917      0.488 2
 UniProt:Q12951-2 FOXI1      0.488 2
 UniProt:Q7KZS0 Q7KZS0      0.488 2
 IntAct:EBI-11522976 CCDC33      0.488 2
 IntAct:EBI-17178025 EP400NL      0.488 2
 UniProt:Q13515 BFSP2      0.488 2
 UniProt:P78424 PO6F2      0.488 2
 UniProt:Q9BZR9 TRIM8  1 0.488 2
 UniProt:Q8WWL2-2 SPIRE2      0.488 2
 UniProt:Q13077 TRAF1  3 0.488 2
 UniProt:Q96HB5 CC120      0.488 2
 UniProt:Q6BCY4-2 CYB5R2      0.488 2
 UniProt:Q8WXI4-2 Q8WXI42      0.488 2
 UniProt:Q01546 KRT76  1 0.488 2
 UniProt:O00303 EIF3F  1 0.488 2
 UniProt:Q86UV6-2 TRIM74      0.488 2
 UniProt:Q8NAJ2 CI106      0.488 2
 UniProt:O95954 FTCD  1 0.488 2
 UniProt:A6NEM1 GG6L9      0.488 2
 IntAct:EBI-12022818 PRR22      0.488 2
 UniProt:B7ZLH0 B7ZLH0      0.488 2
 UniProt:P25800 LMO1  1 0.488 2
 UniProt:Q5W150 YT011      0.488 2
 UniProt:Q13064 MKRN3      0.488 2
 UniProt:Q96KN3 PKNX2      0.488 2
 UniProt:Q76N32-2 CEP68      0.488 2
 UniProt:Q70EL1-9 USP54      0.488 2
 UniProt:Q1A5X7 WHAL1      0.488 4
 UniProt:Q96M29 TEKT5      0.488 2
 UniProt:Q8N4W5 Q8N4W5      0.488 2
 UniProt:Q01196-8 RUNX1      0.488 2
 UniProt:Q9UGK8 SRGEF      0.488 2
 UniProt:P20132 SDS  1 0.488 2
 UniProt:Q5T124-6 UBXN11      0.488 2
 UniProt:Q08043 ACTN3  1 0.488 2
 UniProt:Q92734 TFG  1 0.488 2
 UniProt:Q86XA8 Q86XA8      0.488 2
 UniProt:Q15528-2 MED22      0.488 2
 UniProt:Q8IWG5 Q8IWG5      0.488 2
 UniProt:Q8IUC3 KRA71      0.488 2
 UniProt:Q6IA69 NADSYN1  1 0.488 2
 UniProt:O43716 GATC      0.488 2
 UniProt:Q2M3A8 MRAS1      0.488 2
 UniProt:P54257 HAP1      0.488 2
 UniProt:A1L4K1 FSD2      0.488 2
 UniProt:Q96P16-3 RPRD1A      0.488 2
 UniProt:Q8NCR6 SMRP1      0.488 2
 UniProt:Q9BYV2 TRI54      0.488 2
 UniProt:Q5JST6 EFHC2      0.488 2
 UniProt:Q9ULV5-2 HSF4      0.488 2
 UniProt:Q8N4U5 T11L2      0.488 2
 UniProt:Q96PG8 BBC3B      0.488 2
 UniProt:P26367 PAX6  1 0.488 2
 UniProt:Q02548 PAX5  1 0.488 2
 UniProt:Q12888 TP53BP1  3 0.488 2
 UniProt:P14373 TRIM27  2 0.488 2
 UniProt:P52272 HNRNPM  1 0.488 2
 UniProt:P09683 SCT  1 0.488 2
 UniProt:O88811  2 0.463 2
 UniProt:Q96B67 ARRD3      0.463 2