Reactome | ERP44 [specific granule lumen]

ERP44 [specific granule lumen]

Stable Identifier

R-HSA-6799567

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

specific granule lumen

Synonyms

Endoplasmic reticulum resident protein 44, ERP44_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9BS26 ERP44

Gene Names

ERP44, KIAA0573, TXNDC4, UNQ532/PRO1075

Chain

signal peptide:1-29, chain:30-406

Reference Genes

BioGPS Gene:23071 ERP44

COSMIC (genes):ERP44 ERP44

CTD Gene:23071 ERP44

dbSNP Gene:23071 ERP44

ENSEMBL:ENSG00000023318 ERP44

ENSEMBL_homo_sapiens_GENE:ENSG00000023318.9 ERP44

HGNC:18311 ERP44

KEGG Gene (Homo sapiens):23071 ERP44

Monarch:23071 ERP44

NCBI Gene:23071 ERP44

OMIM:609170 ERP44

UCSC:Q9BS26 ERP44

Reference Transcript

RefSeq:NM_015051.2 ERP44

Other Identifiers

11718353_at

11718354_a_at

11718355_x_at

11718356_at

17096580

208957_PM_at

208957_at

208958_PM_at

208958_at

208959_PM_s_at

208959_s_at

23071

3217733

3217735

3217737

3217738

3217739

3217740

3217741

3217743

3217754

3217755

3217759

3217760

3217761

3217762

3217765

3217766

3217767

3217773

3217774

3217775

3217776

40053_at

8162833

A_23_P373927

A_23_P380092

GE519385

GE53284

GO:0003756

GO:0003824

GO:0005515

GO:0005576

GO:0005615

GO:0005783

GO:0005788

GO:0005789

GO:0005793

GO:0006457

GO:0006986

GO:0009100

GO:0009986

GO:0016853

GO:0031410

GO:0034976

GO:0035580

GO:0043226

GO:0045454

GO:0070062

GO:0140096

GO:1901135

HMNXSV003048538

HMNXSV003055038

Hs.154023.0.S2_3p_at

Hs.154023.0.S3_3p_at

ILMN_1772156

ILMN_2115379

PH_hs_0031876

TC09001416.hg

g13529223_3p_a_at

Participates

as a member of

Specific granule lumen proteins [specific granule lumen] (Homo sapiens)

Other forms of this molecule

ERP44 [extracellular region]

Inferred To

ERP44 [specific granule lumen] (Bos taurus)

ERP44 [specific granule lumen] (Canis familiaris)

ERP44 [specific granule lumen] (Gallus gallus)

ERP44 [specific granule lumen] (Rattus norvegicus)

ERP44 [specific granule lumen] (Sus scrofa)

ERp44 [specific granule lumen] (Drosophila melanogaster)

erp44 [specific granule lumen] (Danio rerio)

erp44 [specific granule lumen] (Xenopus tropicalis)

Erp44 [specific granule lumen] (Mus musculus)

erp-44.1 [specific granule lumen] (Caenorhabditis elegans)

Cross References

RefSeq

NP_055866.1

OpenTargets

ENSG00000023318

GeneCards

Q9BS26

HPA

ENSG00000023318-ERP44

Ensembl

ENSG00000023318, ENST00000262455, ENSP00000262455

PRO

Q9BS26

Pharos - Targets

Q9BS26

HMDB Protein

HMDBP08091

PDB

2R2J, 5XWM, 5GU6, 5GU7, 5HQP

Interactors (10)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P0DTC8 8	2	8 [extracellular region] (R-COV-9755410) 8 [endoplasmic reticulum lumen] (R-COV-9727283)	0.643	3
UniProt:P02452 COL1A1	20	3x4Hyp-3Hyp-GlcGalHyl-COL1A1(23-1464) [endoplasmic reticulum lumen] (R-HSA-2023648) 3x4Hyp-GlcGalHyl-COL1A1(23-1464) [endoplasmic reticulum lumen] (R-HSA-2023667) GlcGalHyl-COL1A1(23-1464) [endoplasmic reticulum lumen] (R-HSA-2023604) GalHyl-COL1A1(23-1464) [endoplasmic reticulum lumen] (R-HSA-2022999) 3x4Hyp-3Hyp-GalHyl-COL1A1(23-1464) [endoplasmic reticulum lumen] (R-HSA-2023559) 3x4Hyp-GalHyl-COL1A1(23-1464) [endoplasmic reticulum lumen] (R-HSA-2023582) COL1A1(23-1464) [endoplasmic reticulum lumen] (R-HSA-1650777) 3x4Hyp-COL1A1(23-1464) [endoplasmic reticulum lumen] (R-HSA-1985659) 3x4Hyp-3Hyp-COL1A1(23-1464) [endoplasmic reticulum lumen] (R-HSA-2022446) 3x4Hyp-5Hyl-COL1A1(23-1464) [endoplasmic reticulum lumen] (R-HSA-2022951) 3x4Hyp-3Hyp-5Hyl-COL1A1(23-1464) [endoplasmic reticulum lumen] (R-HSA-2022954) 5Hyl-COL1A1(23-1464) [endoplasmic reticulum lumen] (R-HSA-1985663) Lysyl-pyrrolyl 5-hydroxylysyl collagen alpha-1(I) chain [extracellular region] (R-HSA-2396137) Lysyl-pyrrolyl 3,4-Hyp 5-Hyl collagen alpha-1(I) chain [extracellular region] (R-HSA-2396440) Lysyl-pyrrolyl 4-Hyp 5-Hyl collagen alpha-1(I) chain [extracellular region] (R-HSA-2396471) Lysyl-pyridinolyl 5-hydroxylysyl collagen alpha-1(I) chain [extracellular region] (R-HSA-2396464) Lysyl-pyridinolyl 4-Hyp 5-Hyl collagen alpha-1(I) chain [extracellular region] (R-HSA-2396068) Lysyl-pyridinolyl 3,4-Hyp 5-Hyl collagen alpha-1(I) chain [extracellular region] (R-HSA-2396388) Dehydrolysinonorlysyl 4-hydroxyprolyl collagen alpha-1(I) chain [extracellular region] (R-HSA-2396315) Dehydrolysinonorlysyl 4-Hyp 5-Gal-Hyl collagen alpha-1(I) chain [extracellular region] (R-HSA-2396441)	0.558	3
UniProt:P05067 APP	20	APP(18-770) [trans-Golgi network membrane] (R-HSA-5229136) APP-C99 [cytosol] (R-HSA-9617603) APP(18-770) [extracellular region] (R-HSA-49335) APP(18-770) [platelet alpha granule lumen] (R-HSA-139835) APP(18-687) [extracellular region] (R-HSA-9010033) APP(688-770) [plasma membrane] (R-HSA-9010028) APP(18-770) [Golgi lumen] (R-HSA-8871509) APP(18-770) [plasma membrane] (R-HSA-9010038) APP(18-671) [endosome lumen] (R-HSA-5693003) APP(714-770) [endosome lumen] (R-HSA-6783325) APP(712-770) [endosome lumen] (R-HSA-6783331) APP(672-770) [endosome lumen] (R-HSA-9010082) APP(672-713) [endosome lumen] (R-HSA-5692993) APP(672-711) [endosome lumen] (R-HSA-6783333) APP(18-770) [endosome lumen] (R-HSA-5229077) p-APP [endoplasmic reticulum lumen] (R-HSA-8957012) APP [endoplasmic reticulum lumen] (R-HSA-8956696) APP(672-711) [extracellular region] (R-HSA-976740) APP(672-711) [cytosol] (R-HSA-877188) APP(672-713) [extracellular region] (R-HSA-879340)	0.556	3
UniProt:P07948 LYN	7	MyrG2-PalmC3-LYN [lysosomal membrane] (R-HSA-9707903) MyrG2-PalmC3-LYN [endocytic vesicle membrane] (R-HSA-9705728) LYN [plasma membrane] (R-HSA-197943) p-Y397-LYN [cytosol] (R-HSA-8942608) p-Y397-LYN [plasma membrane] (R-HSA-2454229) MyrG2-PalmC3-LYN [plasma membrane] (R-HSA-9606875) LYN [cytosol] (R-HSA-354251)	0.556	3
UniProt:Q99708 RBBP8	4	p-S327,T847-RBBP8 [nucleoplasm] (R-HSA-5684083) RBBP8 [nucleoplasm] (R-HSA-912399) Ac-K-RBBP8 [nucleoplasm] (R-HSA-5685955) p-S327,T847,T859-RBBP8 [nucleoplasm] (R-HSA-5684138)	0.527	2
UniProt:P43251 BTD	13	BTD R79C [mitochondrial matrix] (R-HSA-4225085) BTD Q456H [mitochondrial matrix] (R-HSA-4225082) BTD C33Ffs36 [mitochondrial matrix] (R-HSA-4225081) BTD A171T [mitochondrial matrix] (R-HSA-4225080) BTD G34S [mitochondrial matrix] (R-HSA-4225079) BTD R538C [mitochondrial matrix] (R-HSA-4225078) BTD R79C [extracellular region] (R-HSA-3325545) BTD A171T [extracellular region] (R-HSA-3325576) BTD R538C [extracellular region] (R-HSA-3325543) BTD Q456H [extracellular region] (R-HSA-3325552) BTD C33Ffs36 [extracellular region] (R-HSA-3325555) BTD [mitochondrial matrix] (R-HSA-4167525) BTD [extracellular region] (R-HSA-3076888)	0.527	2
UniProt:P01137 TGFB1	7	TGFB1 [extracellular region] (R-HSA-170838) TGFB1(30-278) [extracellular region] (R-HSA-2395367) TGFB1(30-278) [Golgi lumen] (R-HSA-9736812) TGFB1 [Golgi lumen] (R-HSA-177108) TGFB1(30-390) [Golgi lumen] (R-HSA-114705) TGFB1 [plasma membrane] (R-HSA-5146781) TGFB1(30-278) [platelet alpha granule lumen] (R-HSA-65936)	0.527	3
UniProt:Q86YB8 ERO1B	1	ERO1B [endoplasmic reticulum lumen] (R-HSA-4084704)	0.527	2
UniProt:Q8NBK3 SUMF1	1	SUMF1 [endoplasmic reticulum lumen] (R-HSA-1614316)	0.527	2
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.483	4

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