HS(6)-AGRN [lysosomal lumen]

Stable Identifier
R-HSA-2090081
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
lysosomal lumen
Synonyms
AGRN, Agrin, AGRIN_HUMAN
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:O00468 AGRN
Gene Names
AGRN, AGRIN
Chain
signal peptide:1-29, chain:30-2068, chain:30-1102, chain:1103-2068, chain:1103-1863, chain:1864-2068
Reference Genes
BioGPS Gene:375790 AGRN
COSMIC (genes):AGRN AGRN
CTD Gene:375790 AGRN
dbSNP Gene:375790 AGRN
ENSEMBL:ENSG00000188157 AGRN
ENSEMBL_homo_sapiens_GENE:ENSG00000188157.15 AGRN
HGNC:329 AGRN
KEGG Gene (Homo sapiens):375790 AGRN
Monarch:375790 AGRN
NCBI Gene:375790 AGRN
OMIM:103320 AGRN
UCSC:O00468 AGRN
Reference Transcript
Other Identifiers
11732450_s_at
11732451_a_at
16657598
212283_PM_at
212283_at
212285_PM_s_at
212285_s_at
217419_PM_x_at
217419_x_at
33454_at
375790
4053551
4053554
4053565
4053573
4053574
4053575
4053576
4053579
4053580
4053581
4053582
4053583
4053584
4053586
4053588
4053589
4053590
4053591
4053592
4053594
4053595
4053598
4053600
4053602
4053604
4053605
4053606
4053608
4053609
4053610
4053611
4053612
4053613
4053614
4053615
4053616
4053617
4053618
4053619
4053627
4053629
4053631
4053632
4053633
4053634
4053635
4053636
4053637
4053638
7896822
A_23_P343411
A_24_P24819
A_24_P358462
GO:0002162
GO:0005198
GO:0005200
GO:0005201
GO:0005509
GO:0005515
GO:0005576
GO:0005604
GO:0005615
GO:0005764
GO:0005773
GO:0005794
GO:0005796
GO:0005886
GO:0006351
GO:0006355
GO:0007010
GO:0007165
GO:0007213
GO:0007528
GO:0016020
GO:0023052
GO:0030154
GO:0030312
GO:0031012
GO:0033691
GO:0034330
GO:0035374
GO:0043113
GO:0043202
GO:0043226
GO:0043236
GO:0043395
GO:0043547
GO:0045162
GO:0045202
GO:0045887
GO:0045944
GO:0046872
GO:0048856
GO:0050808
GO:0051491
GO:0061024
GO:0062023
GO:0070062
HMNXSV003003886
Hs.273330.1.S1_3p_at
Hs.273330.2.S1_3p_a_at
ILMN_1770454
ILMN_2234605
PH_hs_0032416
TC01000024.hg
Participates
as a member of
Other forms of this molecule
AGRN(30-2045) [lysosomal lumen]
HS(1)-AGRN [Golgi lumen]
HS(2)-AGRN [Golgi lumen]
HS(3)-AGRN [Golgi lumen]
HS(4)-AGRN [Golgi lumen]
HS(6)-AGRN [Golgi lumen]
HS(5)-AGRN [Golgi lumen]
Heparan-AGRN [Golgi lumen]
Heparan(1)-AGRN [Golgi lumen]
Heparan(2)-AGRN [Golgi lumen]
Heparan(4)-AGRN [Golgi lumen]
Heparan(3)-AGRN [Golgi lumen]
AGRN(30-2045) [Golgi lumen]
XylS-AGRN(30-2045) [Golgi lumen]
Gal-Xyl-AGRN [Golgi lumen]
HS(4)-AGRN [plasma membrane]
HS(6)-AGRN [plasma membrane]
HS(2)-AGRN [plasma membrane]
HS(1)-AGRN [plasma membrane]
HS(3)-AGRN [plasma membrane]
HS(5)-AGRN [plasma membrane]
AGRN(30-2045) [extracellular region]
Gal-Gal-Xyl-AGRN [Golgi lumen]
GlcA-Gal-Gal-Xyl-AGRN [Golgi lumen]
Inferred To
AGRN [lysosomal lumen] (Bos taurus)
AGRN [lysosomal lumen] (Canis familiaris)
AGRN [lysosomal lumen] (Sus scrofa)
HS(6)-AGRN [lysosomal lumen] (Caenorhabditis elegans)
HS(6)-AGRN [lysosomal lumen] (Mus musculus)
HS(6)-AGRN [lysosomal lumen] (Rattus norvegicus)
itx-1 [lysosomal lumen] (Caenorhabditis elegans)
Homologues of HS(6)-AGRN [lysosomal lumen] (Caenorhabditis elegans)
SP2353 [lysosomal lumen] (Drosophila melanogaster)
Modified Residues
Name
O-xylosyl-L-serine (ChEBI:63666) at unknown position
Modification
beta-D-IdoA-(1->4)-alpha-D-GlcNS6S-(1->4)-beta-D-IdoA2S-(1->4)-alpha-D-GlcNS3S-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl-yl group
PsiMod Name
O-xylosyl-L-serine
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O3-xylosylserine.
Cross References
RefSeq
OpenTargets
HPA
GeneCards
Ensembl
PRO
Pharos - Targets
Orphanet
PDB
Interactors (4)
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