Reactome | AMOT-1 [cytosol]

AMOT-1 [cytosol]

Stable Identifier

R-HSA-2028607

Type

Genes and Transcripts [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

AMOT, 130 kd, Angiomotin, 130 kd

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q4VCS5-1 AMOT

Gene Names

AMOT, KIAA1071

Participates

as a member of

AMOT proteins [cytosol] (Homo sapiens)

Inferred To

Amot [cytosol] (Mus musculus)

Amot [cytosol] (Rattus norvegicus)

AMOT [cytosol] (Bos taurus)

AMOT [cytosol] (Gallus gallus)

AMOT [cytosol] (Sus scrofa)

AMOT-1 [cytosol] (Canis familiaris)

amot [cytosol] (Xenopus tropicalis)

Cross References

RefSeq

NP_573572.1, XP_047297813.1, XP_011529177.1, XP_005262144.1, NP_001373927.1, NP_001373928.1, XP_016884778.1, XP_005262147.1, XP_047297812.1, NP_001106962.1

OpenTargets

ENSG00000126016

ENSEMBL

ENSP00000305557, ENST00000304758, ENST00000371959, ENSP00000361027, ENSG00000126016

HPA

ENSG00000126016-AMOT

GeneCards

AMOT

PRO

Q4VCS5

Pharos - Targets

Q4VCS5

GlyGen

Q4VCS5

PDB

7LP3, 7LP5, 7NPB, 7NNE, 7NND, 7NN2, 7LP2, 7NPG, 7NMX, 7NMA, 7NMW, 6JJX, 7OQU, 7OQW, 7OQS, 7OQG, 7OQJ, 7NP2

Interactors (11)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P35240 NF2	1	NF2 [plasma membrane] (R-HSA-5669168)	0.882	10
UniProt:P46937 YAP1	8	YAP1 [cytosol] (R-HSA-1253345) YAP1 [nucleoplasm] (R-HSA-1253322) p-5S-YAP1 [cytosol] (R-HSA-2028554) p-S127-YAP1 [cytosol] (R-HSA-2028553) p-Y-YAP1 [nucleoplasm] (R-HSA-8937857) p-Y-YAP1 [cytosol] (R-HSA-8937843) p-Y407-YAP1 [nucleoplasm] (R-HSA-8956661) p-Y407-YAP1 [cytosol] (R-HSA-9865208)	0.802	6
UniProt:Q8N3R9 MPP5	2	MPP5 [plasma membrane] (R-HSA-419969) MPP5 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-9689606)	0.802	7
UniProt:Q8IX03 WWC1	1	WWC1 [cytosol] (R-HSA-2038400)	0.615	3
UniProt:P40692 MLH1	3	MLH1 [nucleoplasm] (R-HSA-912495) MLH1 H329P [nucleoplasm] (R-HSA-5444512) MLH1 S252* [nucleoplasm] (R-HSA-5444526)	0.527	2
UniProt:Q9NPJ6 MED4	1	MED4 [nucleoplasm] (R-HSA-350263)	0.527	2
UniProt:Q9GZV5 WWTR1	3	WWTR1 [nucleoplasm] (R-HSA-1629775) WWTR1 [cytosol] (R-HSA-1629773) p-S89-WWTR1 [cytosol] (R-HSA-2028665)	0.527	2
UniProt:P09917 ALOX5	6	p-S272-ALOX5 [nuclear envelope] (R-HSA-2318765) ALOX5 [cytosol] (R-HSA-429010) ALOX5 [ficolin-1-rich granule lumen] (R-HSA-6801302) ALOX5 [extracellular region] (R-HSA-6806468) ALOX5 [secretory granule lumen] (R-HSA-6801306) p-S272-ALOX5 [cytosol] (R-HSA-265276)	0.527	2
UniProt:Q96PU5 NEDD4L	2	NEDD4L [nucleoplasm] (R-HSA-2176420) NEDD4L [cytosol] (R-HSA-976003)	0.527	2
UniProt:P46662	1	Nf2 [plasma membrane] (R-MMU-5669168)	0.499	2
UniProt:Q9Y6K9 IKBKG	12	IKBKG [cytosol] (R-HSA-168108) Ub-285-IKBKG [cytosol] (R-HSA-741397) K63polyUb-IKBKG [cytosol] (R-HSA-202530) IKBKG [nucleoplasm] (R-HSA-4755413) monoSUMO1-K277,K309-IKBKG [nucleoplasm] (R-HSA-4755449) IKBKG 420Wext447 [cytosol] (R-HSA-5262978) IKBKG R175P [cytosol] (R-HSA-5262916) IKBKG R173G [cytosol] (R-HSA-5262966) IKBKG C417R [cytosol] (R-HSA-5262858) IKBKG E391* [cytosol] (R-HSA-5262924) IKBKG L153R [cytosol] (R-HSA-5262879) IKBKG D406V [cytosol] (R-HSA-5262943)	0.499	3

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