p-S89-WWTR1 [cytosol]

Stable Identifier
R-HSA-2028665
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
p-WWTR1, phosphorylated WW domain-containing transcription regulator protein 1, phosphorylated Transcriptional coactivator with PDZ-binding motif, p-TAZ
Locations in the PathwayBrowser
Expand all
Literature References
PubMed ID Title Journal Year
18227151 TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway

Lei, Q, Guan, KL, Xiong, Y, Pei, XH, Zhang, H, Zha, ZY, Zhao, B, Bai, F, Zhao, S

Mol Cell Biol 2008
External Reference Information
External Reference
UniProt:Q9GZV5 WWTR1
Gene Names
WWTR1, TAZ
Chain
chain:1-400
Reference Genes
BioGPS Gene:25937 WWTR1
COSMIC (genes):TAZ WWTR1
COSMIC (genes):WWTR1 WWTR1
CTD Gene:25937 WWTR1
dbSNP Gene:25937 WWTR1
ENSEMBL:ENSG00000018408 WWTR1
HGNC:24042 WWTR1
KEGG:hsa:25937 WWTR1
Monarch:25937 WWTR1
NCBI Gene:25937 WWTR1
OMIM:607392 WWTR1
UCSC:Q9GZV5 WWTR1
Reference Transcript
Other Identifiers
11755099_a_at
11759482_at
11759483_at
202132_PM_at
202132_at
202133_PM_at
202133_at
202134_PM_s_at
202134_s_at
25937
2667757
2700407
2700408
2700409
2700410
2700411
2700412
2700413
2700414
2700415
2700417
2700418
2700425
2700431
2700432
2700433
2700437
2700459
2700460
2700461
2700462
2700463
2700464
2700470
2700471
2700473
2700474
2700477
2700479
2700480
33876_at
8091422
A_23_P29769
A_24_P944383
A_24_P944390
A_32_P6868
A_33_P3605352
GE56247
GE82008
GO:0000122
GO:0001649
GO:0001894
GO:0001933
GO:0003013
GO:0003015
GO:0003712
GO:0003713
GO:0003714
GO:0005515
GO:0005634
GO:0005654
GO:0005667
GO:0005737
GO:0005829
GO:0005886
GO:0006355
GO:0006469
GO:0008284
GO:0010718
GO:0016567
GO:0016604
GO:0017145
GO:0030154
GO:0030163
GO:0031146
GO:0032835
GO:0035264
GO:0035329
GO:0042803
GO:0043226
GO:0044782
GO:0045599
GO:0045669
GO:0045944
GO:0048762
GO:0048856
GO:0060090
GO:0060271
GO:0060395
GO:0060828
GO:0060993
GO:0072307
GO:0090090
GO:0140110
GO:1900182
HMNXSV003013267
HMNXSV003057122
Hs.24341.0.A2_3p_at
Hs.24341.0.A3_3p_at
ILMN_1787115
PH_hs_0002143
PH_hs_0035163
g13346497_3p_a_at
Participates
as a component of
as an input of
as an output of
Other forms of this molecule
WWTR1 [nucleoplasm]
WWTR1 [cytosol]
Inferred To
phospho-wwtr1 [cytosol] (Danio rerio)
phospho-wwtr1 [cytosol] (Xenopus tropicalis)
phospho-WWTR1 [cytosol] (Bos taurus)
phospho-WWTR1 [cytosol] (Canis familiaris)
phospho-WWTR1 [cytosol] (Sus scrofa)
phospho-p-S89-WWTR1 [cytosol] (Gallus gallus)
phospho-Wwtr1 [cytosol] (Mus musculus)
phospho-Wwtr1 [cytosol] (Rattus norvegicus)
phospho-yap-1 [cytosol] (Caenorhabditis elegans)
Modified Residues
Name
O-phospho-L-serine at 89
Coordinate
89
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
OpenTargets
ENSEMBL
HPA
PRO
Pharos - Targets
Orphanet
PDB
Interactors (28)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q15561 TEAD4  1 0.888 11
 UniProt:Q99594 TEAD3  1 0.745 5
 UniProt:P62258 YWHAE  1 0.738 4
 UniProt:P61981 YWHAG  1 0.738 5
 UniProt:Q15562 TEAD2  1 0.643 5
 UniProt:P27348 YWHAQ  1 0.643 3
 UniProt:Q04917 YWHAH  1 0.643 3
 UniProt:O95835 LATS1  2 0.641 5
 UniProt:P35222 CTNNB1  20 0.641 4
 UniProt:Q969T9 WBP2      0.61 6
 UniProt:Q15599 NHRF2      0.602 3
 UniProt:Q9BZD6 TMG4      0.602 4
 UniProt:O14641 DVL2  5 0.591 4
 UniProt:Q14160 SCRIB  1 0.59 3
 UniProt:P62262 1433E      0.571 3
 UniProt:Q9Y297 BTRC  2 0.564 2
 IntAct:EBI-25847655 CCSB      0.556 3
 UniProt:Q15562-2 TEAD2      0.556 3
 UniProt:P28347-2 TEAD1      0.556 3
 UniProt:Q9NUJ3 T11L1      0.556 3
 UniProt:Q14005-2 Q140052      0.556 3
 UniProt:Q96LT6 CA074      0.556 3
 UniProt:Q8WWV3 RT4I1      0.556 3
 UniProt:Q01196 RUNX1  5 0.527 2
 UniProt:Q4VCS5 AMOT      0.527 2
 UniProt:P28347 TEAD1  1 0.527 3
 UniProt:O14640 DVL1  4 0.524 2
 UniProt:P78371 CCT2  3 0.499 2
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