Reactome | ARF1 [Golgi membrane]

ARF1 [Golgi membrane]

Stable Identifier

R-HSA-199971

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

Golgi membrane

Synonyms

Arf1

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P84077 ARF1

Gene Names

ARF1

Chain

initiator methionine:1, chain:2-181

Reference Genes

BioGPS Gene:375 ARF1

COSMIC (genes):ARF1 ARF1

CTD Gene:375 ARF1

dbSNP Gene:375 ARF1

ENSEMBL:ENSG00000143761 ARF1

HGNC:652 ARF1

KEGG Gene (Homo sapiens):375 ARF1

Monarch:375 ARF1

NCBI Gene:375 ARF1

OMIM:103180 ARF1

UCSC:P84077 ARF1

Reference Transcript

Other Identifiers

0000840600

11719759_s_at

16678303

18670609

18670610

18670615

18670616

18670617

18670618

18670619

200065_PM_s_at

200065_s_at

208750_s_at

2383733

2383734

2383735

2383736

2383737

2383754

2383755

2383756

2383758

2383759

2383761

2383762

2383763

2383764

2383765

2383766

2383767

2383768

2383769

244504_3p_x_at

244504_x_at

33987_at

375

7892830

7893592

7893609

7894011

7894336

7894413

7894767

7894808

7895084

7895110

7895484

7895881

7896158

7896375

7896586

7896657

7910229

A_23_P201086

A_24_P190894

A_24_P259490

GE63168

GO:0000139

GO:0000166

GO:0000278

GO:0000287

GO:0002090

GO:0002376

GO:0003674

GO:0003723

GO:0003924

GO:0005515

GO:0005525

GO:0005575

GO:0005576

GO:0005615

GO:0005622

GO:0005737

GO:0005768

GO:0005770

GO:0005777

GO:0005778

GO:0005794

GO:0005802

GO:0005829

GO:0005886

GO:0005925

GO:0006629

GO:0006661

GO:0006810

GO:0006878

GO:0006886

GO:0007010

GO:0007015

GO:0007034

GO:0007049

GO:0007165

GO:0007267

GO:0008150

GO:0009058

GO:0012505

GO:0014069

GO:0015031

GO:0016020

GO:0016192

GO:0019003

GO:0019886

GO:0019904

GO:0022607

GO:0030017

GO:0030054

GO:0030137

GO:0030154

GO:0030234

GO:0031252

GO:0031410

GO:0032991

GO:0034315

GO:0034330

GO:0034379

GO:0035722

GO:0042592

GO:0043005

GO:0043167

GO:0043226

GO:0044403

GO:0045202

GO:0045807

GO:0045956

GO:0048471

GO:0048856

GO:0050690

GO:0050714

GO:0050790

GO:0051301

GO:0055085

GO:0055108

GO:0060292

GO:0060999

GO:0061024

GO:0065003

GO:0070062

GO:0070142

GO:0097061

GO:0097212

GO:0098586

GO:0098974

GO:0098978

GO:1902307

GO:1902824

GO:1902953

GO:1903725

GO:1990386

GO:1990583

HMNXSV003032236

Hs.282187.0.A1_3p_x_at

Hs.74571.0.A1_3p_a_at

ILMN_1661458

ILMN_1802203

ILMN_2330948

M84332_at

PH_hs_0023485

TC01001884.hg

g3360490_3p_a_at

Participates

as a component of

as an input of

PLEKHA3,8 bind PI4P, ARF1 (Homo sapiens)

Other forms of this molecule

ARF1 [cytosol]

Inferred To

arrF [Golgi membrane] (Dictyostelium discoideum)

arrA [Golgi membrane] (Dictyostelium discoideum)

arrK [Golgi membrane] (Dictyostelium discoideum)

Arf1 [Golgi membrane] (Mus musculus)

Arf1 [Golgi membrane] (Rattus norvegicus)

arf1 [Golgi membrane] (Schizosaccharomyces pombe)

arf2a [Golgi membrane] (Danio rerio)

arrC [Golgi membrane] (Dictyostelium discoideum)

Homologues of ARF1 [Golgi membrane] (Dictyostelium discoideum)

Homologues of ARF1 [Golgi membrane] (Saccharomyces cerevisiae)

ARF1 [Golgi membrane] (Bos taurus)

ARF1 [Golgi membrane] (Canis familiaris)

ARF1 [Golgi membrane] (Dictyostelium discoideum)

ARF1 [Golgi membrane] (Gallus gallus)

ARF1 [Golgi membrane] (Plasmodium falciparum)

ARF1 [Golgi membrane] (Saccharomyces cerevisiae)

ARF1 [Golgi membrane] (Sus scrofa)

arrE [Golgi membrane] (Dictyostelium discoideum)

ARF2 [Golgi membrane] (Saccharomyces cerevisiae)

Arf79F [Golgi membrane] (Drosophila melanogaster)

arrL [Golgi membrane] (Dictyostelium discoideum)

arfA [Golgi membrane] (Dictyostelium discoideum)

arf-3 [Golgi membrane] (Caenorhabditis elegans)

arrH [Golgi membrane] (Dictyostelium discoideum)

arrJ [Golgi membrane] (Dictyostelium discoideum)

Cross References

RefSeq

NP_001019399.1, NP_001649.1, NP_001019397.1, NP_001019398.1

OpenTargets

ENSG00000143761

ZINC - Substances

ARF1_HUMAN

ZINC target

P84077

PRO

P84077

PDB

1RE0, 1HUR, 6FAE, 6D83, 4HMY, 6CM9, 6CRI, 1U81, 6DFF, 6D84, 3O47

Target Pathogen

5b2801b3be737e35a6defa55, 5b2801b3be737e35a6df1bfb, 5b2801b3be737e35a6dec490, 5b354852be737e166372e8eb, 5b2801b3be737e35a6deeb1d

GeneCards

P84077

HPA

ENSG00000143761-ARF1

Ensembl

ENST00000541182, ENST00000272102, ENST00000540651, ENSP00000272102, ENSP00000440005, ENSP00000442980, ENSG00000143761

Orphanet

27691

ZINC - Predictions - Purchasable

ARF1_HUMAN

HMDB Protein

HMDBP01962

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q99418 CYTH2	2	CYTH2 [Golgi membrane] (R-HSA-8847829) CYTH2 [cytosol] (R-HSA-8847831)	0.722	5
UniProt:P53365 ARFIP2	1	ARFIP2 [cytosol] (R-HSA-6813848)	0.488	2
1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate [ChEBI:16851]	7	PI(3,5)P2 [plasma membrane] (R-ALL-1806224) PI(3,5)P2 [phagophore assembly site membrane] (R-ALL-5692959) PI(3,5)P2 [Golgi membrane] (R-ALL-1806290) PI(3,5)P2 [early endosome membrane] (R-ALL-1806205) PI(3,5)P2 [late endosome membrane] (R-ALL-1806289) PI(3,5)P2 [endoplasmic reticulum membrane] (R-ALL-6809774) PI(3,5)P2 [lysosomal membrane] (R-ALL-5334668)	0.462	2
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate [ChEBI:18348]	6	PI(4,5)P2 [endoplasmic reticulum membrane] (R-ALL-2023856) PI(4,5)P2 [plasma membrane] (R-ALL-179856) PI(4,5)P2 [Golgi membrane] (R-ALL-1806165) PI(4,5)P2 [nucleoplasm] (R-ALL-6810412) PI(4,5)P2 [cytoplasmic vesicle membrane] (R-ALL-8874467) PI(4,5)P2 [early endosome membrane] (R-ALL-8849966)	0.462	2