Reactome | SNAP25 [tertiary granule membrane]

SNAP25 [tertiary granule membrane]

Stable Identifier

R-HSA-6806142

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

tertiary granule membrane

Synonyms

Synaptosomal-associated protein 25

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External Reference Information

External Reference

UniProt:P60880 SNAP25

Gene Names

SNAP25, SNAP

Chain

chain:1-206

Reference Genes

COSMIC (genes):SNAP25 SNAP25

dbSNP Gene:6616 SNAP25

ENSEMBL:ENSG00000132639 SNAP25

Participates

as a member of

Tertiary granule membrane proteins [tertiary granule membrane] (Homo sapiens)

Other forms of this molecule

SNAP25(1-197) [plasma membrane]

SNAP25(198-206) [cytosol]

SNAP25(1-198) [plasma membrane]

SNAP25(199-206) [cytosol]

SNAP25 [specific granule membrane]

SNAP25 [plasma membrane]

Inferred To

sec9 [tertiary granule membrane] (Schizosaccharomyces pombe)

snap25 [tertiary granule membrane] (Xenopus tropicalis)

SEC9 [tertiary granule membrane] (Saccharomyces cerevisiae)

aex-4 [tertiary granule membrane] (Caenorhabditis elegans)

SNAP25 [tertiary granule membrane] (Bos taurus)

SNAP25 [tertiary granule membrane] (Canis familiaris)

SNAP25 [tertiary granule membrane] (Dictyostelium discoideum)

SNAP25 [tertiary granule membrane] (Gallus gallus)

SNAP25 [tertiary granule membrane] (Plasmodium falciparum)

SNAP25 [tertiary granule membrane] (Sus scrofa)

ric-4 [tertiary granule membrane] (Caenorhabditis elegans)

Snap25 [tertiary granule membrane] (Drosophila melanogaster)

Snap25 [tertiary granule membrane] (Mus musculus)

Snap25 [tertiary granule membrane] (Rattus norvegicus)

cspA [tertiary granule membrane] (Dictyostelium discoideum)

SPO20 [tertiary granule membrane] (Saccharomyces cerevisiae)

Homologues of SNAP25 [tertiary granule membrane] (Caenorhabditis elegans)

Homologues of SNAP25 [tertiary granule membrane] (Dictyostelium discoideum)

Homologues of SNAP25 [tertiary granule membrane] (Drosophila melanogaster)

Homologues of SNAP25 [tertiary granule membrane] (Saccharomyces cerevisiae)

Snap24 [tertiary granule membrane] (Drosophila melanogaster)

snap25a [tertiary granule membrane] (Danio rerio)

Modified Residues

Name

S-palmitoyl-L-cysteine at 85

Coordinate

PsiMod Name

S-palmitoyl-L-cysteine [MOD:00115]

PsiMod Definition

A protein modification that effectively converts an L-cysteine residue to S-palmitoyl-L-cysteine.

Name

S-palmitoyl-L-cysteine at 88

Coordinate

PsiMod Name

S-palmitoyl-L-cysteine [MOD:00115]

PsiMod Definition

A protein modification that effectively converts an L-cysteine residue to S-palmitoyl-L-cysteine.

Name

S-palmitoyl-L-cysteine at 90

Coordinate

PsiMod Name

S-palmitoyl-L-cysteine [MOD:00115]

PsiMod Definition

A protein modification that effectively converts an L-cysteine residue to S-palmitoyl-L-cysteine.

Name

S-palmitoyl-L-cysteine at 92

Coordinate

PsiMod Name

S-palmitoyl-L-cysteine [MOD:00115]

PsiMod Definition

A protein modification that effectively converts an L-cysteine residue to S-palmitoyl-L-cysteine.

Interactors (9)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P0DTD1-PRO_0000449622 REP			0.556	3
UniProt:O75558 STX11			0.553	2
UniProt:P00533 EGFR	20	p-6Y-EGFR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869138) p-5Y-EGFRvIII [plasma membrane] (R-HSA-1248649) EGFRvIII [plasma membrane] (R-HSA-1214162) p-6Y-EGFR E746_A750del;T790M [plasma membrane] (R-HSA-1182985) p-6Y-EGFR L858R;T790M [plasma membrane] (R-HSA-1182984) p-6Y-EGFR A767_V769dup [plasma membrane] (R-HSA-1996343) p-6Y-EGFR N771_H773dup [plasma membrane] (R-HSA-1996342) p-6Y-EGFR K739_I744dup [plasma membrane] (R-HSA-1996346) p-6Y-EGFR D770_N771insNPG [plasma membrane] (R-HSA-1996335) p-6Y-EGFR E746_A750del [plasma membrane] (R-HSA-1181214) p-6Y-EGFR L858R [plasma membrane] (R-HSA-1173211) p-6Y-EGFR G719S [plasma membrane] (R-HSA-1169417) p-6Y-EGFR L747_P753delinsS [plasma membrane] (R-HSA-1228038) p-6Y-EGFR L747_A750delinsP [plasma membrane] (R-HSA-1228044) p-6Y-EGFR L747_T751del [plasma membrane] (R-HSA-1228041) p-6Y-EGFR L747_S752del [plasma membrane] (R-HSA-1228040) p-6Y-EGFR L747_T751delinsP [plasma membrane] (R-HSA-1228042) p-6Y-EGFR E746_T751delinsA [plasma membrane] (R-HSA-1228037) p-6Y-EGFR E746_S752delinsV [plasma membrane] (R-HSA-1228039) p-6Y-EGFR L861Q [plasma membrane] (R-HSA-1177541)	0.553	2
UniProt:Q16623 STX1A	5	STX1A [plasma membrane] (R-HSA-449128) STX1A(?-288) [plasma membrane] (R-HSA-5246518) STX1A(1-?) [cytosol] (R-HSA-3065964) STX1A [cytosol] (R-HSA-9609866) STX1A [endoplasmic reticulum membrane] (R-HSA-9609878)	0.547	3
UniProt:P61764 STXBP1	2	STXBP1 [plasma membrane] (R-HSA-2980862) STXBP1 [cytosol] (R-HSA-6794256)	0.527	2
UniProt:P84077 ARF1	2	ARF1 [Golgi membrane] (R-HSA-199971) ARF1 [cytosol] (R-HSA-200826)	0.512	5
UniProt:Q15811 ITSN1	1	ITSN1 [cytosol] (R-HSA-3006481)	0.502	2
UniProt:Q8IUH5 ZDH17			0.489	3
UniProt:Q9Y3C0 WASC3			0.488	2

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