Reactome | RHOBTB1 [endosome membrane]

RHOBTB1 [endosome membrane]

Stable Identifier

R-HSA-194899

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endosome membrane

Synonyms

RhoBTB1

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O94844 RHOBTB1

Gene Names

RHOBTB1, KIAA0740

Chain

chain:1-696

Reference Genes

BioGPS Gene:9886 RHOBTB1

COSMIC (genes):RHOBTB1 RHOBTB1

CTD Gene:9886 RHOBTB1

dbSNP Gene:9886 RHOBTB1

ENSEMBL:ENSG00000072422 RHOBTB1

HGNC:18738 RHOBTB1

KEGG Gene (Homo sapiens):9886 RHOBTB1

Monarch:9886 RHOBTB1

NCBI Gene:9886 RHOBTB1

OMIM:607351 RHOBTB1

UCSC:O94844 RHOBTB1

Reference Transcript

Other Identifiers

0002100242

0004590138

11719549_a_at

11719550_x_at

11719551_s_at

11719552_a_at

11748460_a_at

11748461_x_at

16714699

212651_at

3291150

3291152

3291153

3291154

3291155

3291156

3291157

3291158

3291162

3291164

3291167

3291168

3291176

3291179

3291182

3291183

3291191

3291192

3291205

3291206

3291207

3291208

3291226

3291231

39771_at

7933821

9886

A_24_P158536

A_33_P3348288

GE53451

GO:0000166

GO:0000902

GO:0003674

GO:0003924

GO:0005515

GO:0005525

GO:0005575

GO:0005622

GO:0005737

GO:0005829

GO:0005856

GO:0005886

GO:0005938

GO:0006810

GO:0007010

GO:0007015

GO:0007165

GO:0007264

GO:0008150

GO:0008360

GO:0016192

GO:0019899

GO:0019901

GO:0030036

GO:0030865

GO:0031410

GO:0032956

GO:0042995

GO:0043167

GO:0043226

GO:0043231

GO:0043652

GO:0048856

GO:0051056

GO:0061024

Hs.15099.0.S1_3p_at

ILMN_1672793

ILMN_1731831

ILMN_1795255

ILMN_2376502

PH_hs_0028778

TC10001320.hg

TC10002665.hg

Participant Of

input

RHOBTB1 binds GTP

hasComponent

RHOBTB1:GTP [endosome membrane]

Inferred To

rac1B [endosome membrane] (Dictyostelium discoideum)

RhoBTB [endosome membrane] (Drosophila melanogaster)

racC [endosome membrane] (Dictyostelium discoideum)

racG [endosome membrane] (Dictyostelium discoideum)

rhobtb1 [endosome membrane] (Danio rerio)

RHOBTB1 [endosome membrane] (Canis familiaris)

RHOBTB1 [endosome membrane] (Dictyostelium discoideum)

RHOBTB1 [endosome membrane] (Gallus gallus)

RHOBTB1 [endosome membrane] (Sus scrofa)

rac1A [endosome membrane] (Dictyostelium discoideum)

racD [endosome membrane] (Dictyostelium discoideum)

racE [endosome membrane] (Dictyostelium discoideum)

racF1 [endosome membrane] (Dictyostelium discoideum)

racJ [endosome membrane] (Dictyostelium discoideum)

Homologues of RHOBTB1 [endosome membrane] (Dictyostelium discoideum)

larp4b [endosome membrane] (Xenopus tropicalis)

racF2 [endosome membrane] (Dictyostelium discoideum)

racN [endosome membrane] (Dictyostelium discoideum)

racQ [endosome membrane] (Dictyostelium discoideum)

Rhobtb1 [endosome membrane] (Mus musculus)

Rhobtb1 [endosome membrane] (Rattus norvegicus)

rac1C [endosome membrane] (Dictyostelium discoideum)

racH [endosome membrane] (Dictyostelium discoideum)

racL [endosome membrane] (Dictyostelium discoideum)

racB [endosome membrane] (Dictyostelium discoideum)

racM [endosome membrane] (Dictyostelium discoideum)

Cross References

RefSeq

NP_001229288.1, XP_006718148.1, NP_055651.1, XP_016872490.1, XP_006718147.1, XP_011538726.1, XP_016872489.1

OpenTargets

ENSG00000072422

GeneCards

O94844

HPA

ENSG00000072422-RHOBTB1

Ensembl

ENSG00000072422, ENSP00000350595, ENST00000337910, ENST00000357917, ENSP00000338671

PRO

O94844

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P61981 YWHAG	1	YWHAG [cytosol] (R-HSA-380312)	0.556	3
UniProt:O60260-5 PRKN			0.556	3
UniProt:Q92993 KAT5	1	KAT5 [nucleoplasm] (R-HSA-3321979)	0.556	3
UniProt:Q8TAP4-4 LMO3			0.556	3
UniProt:Q15047-2 SETDB1			0.556	3
UniProt:P17252 PRKCA	8	p-T497,T638,S657-PRKCA [nucleoplasm] (R-HSA-5223292) PRKCA [cytosol] (R-HSA-58196) p-T497-PRKCA [cytosol] (R-HSA-5218731) p-T497,T638,S657-PRKCA [cytosol] (R-HSA-4332337) pT497,T638,S657-PRKCA [plasma membrane] (R-HSA-4332340) PRKCA [plasma membrane] (R-HSA-156469) PRKCA [photoreceptor disc membrane] (R-HSA-2648987) PRKCA [nucleoplasm] (R-HSA-450530)	0.556	3
UniProt:Q7L5N1 COPS6	2	COPS6 [nucleoplasm] (R-HSA-5697026) COPS6 [cytosol] (R-HSA-416961)	0.527	5

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