Reactome | PLA2G10 [extracellular region]

PLA2G10 [extracellular region]

Stable Identifier

R-HSA-1498793

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

Group 10 secretory phospholipase A2, sPLA2-X

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:O15496 PLA2G10

Gene Names

PLA2G10

Chain

signal peptide:1-31, propeptide:32-42, chain:43-165

Reference Genes

BioGPS Gene:8399 PLA2G10

COSMIC (genes):PLA2G10 PLA2G10

CTD Gene:8399 PLA2G10

dbSNP Gene:8399 PLA2G10

ENSEMBL:ENSG00000069764 PLA2G10

ENSEMBL:ENSG00000276870 PLA2G10

HGNC:9029 PLA2G10

KEGG Gene (Homo sapiens):8399 PLA2G10

Monarch:8399 PLA2G10

NCBI Gene:8399 PLA2G10

OMIM:603603 PLA2G10

UCSC:O15496 PLA2G10

Reference Transcript

RefSeq:NM_003561.2 PLA2G10

Other Identifiers

0002230338

11730699_at

16824109

17121440

207222_at

33052_at

3648396

3649585

3649651

3650604

3650651

3651757

3654506

3654610

3655306

3655497

3656083

3667026

3667077

3681491

3681492

3681495

3681498

3681502

3681503

3681504

3681505

3681506

3681525

3681526

3681527

3681530

3681531

3681532

3681533

3681556

3681557

3681559

3681560

3681638

3682291

3682331

3684957

3686663

3686685

3686855

3686868

3698869

3779196

7999588

8399

ADDON001942.hg

A_21_P0011456

A_23_P88767

GE59596

GO:0000003

GO:0000902

GO:0001669

GO:0002376

GO:0003674

GO:0003847

GO:0004620

GO:0004623

GO:0005509

GO:0005515

GO:0005543

GO:0005575

GO:0005576

GO:0005615

GO:0005622

GO:0005737

GO:0005764

GO:0005773

GO:0006629

GO:0006644

GO:0006654

GO:0006658

GO:0006810

GO:0006950

GO:0007267

GO:0007411

GO:0008150

GO:0008289

GO:0009056

GO:0009058

GO:0010744

GO:0010884

GO:0016042

GO:0016787

GO:0019369

GO:0030154

GO:0031410

GO:0032270

GO:0032308

GO:0034374

GO:0034638

GO:0034641

GO:0036148

GO:0036149

GO:0036150

GO:0036151

GO:0036152

GO:0040011

GO:0042592

GO:0042632

GO:0043030

GO:0043167

GO:0043226

GO:0043433

GO:0044281

GO:0046337

GO:0046470

GO:0046471

GO:0046473

GO:0046872

GO:0047498

GO:0048856

GO:0050482

GO:0051607

GO:0051977

GO:0062234

GO:0090238

GO:0090370

GO:0102567

GO:0102568

GO:2000344

HMNXSV003011260

HMNXSV003032064

ILMN_1762561

PH_hs_0008541

TC16000885.hg

TC16001782.hg

g4505844_3p_at

Participates

as a component of

PLA2G10:Ca2+ [extracellular region] (Homo sapiens)

Inferred To

PLA2G10 [extracellular region] (Bos taurus)

PLA2G10 [extracellular region] (Canis familiaris)

PLA2G10 [extracellular region] (Gallus gallus)

PLA2G10 [extracellular region] (Sus scrofa)

pla2g10 [extracellular region] (Danio rerio)

Ghost homologue of PLA2G10 [extracellular region] (Xenopus tropicalis)

Pla2g10 [extracellular region] (Mus musculus)

Pla2g10 [extracellular region] (Rattus norvegicus)

Cross References

RefSeq

NP_003552.1

Guide to Pharmacology - Targets

1422

OpenTargets

ENSG00000069764

ZINC - Substances

PA2GX_HUMAN

ZINC target

O15496

PRO

O15496

GlyGen

O15496

PDB

4UY1, 1LE7, 5G3M, 5OWC, 5OW8, 6G5J, 1LE6

ZINC - Investigational

PA2GX_HUMAN

GeneCards

O15496

HPA

ENSG00000069764-PLA2G10

Ensembl

ENSP00000393847, ENSG00000069764, ENST00000438167, ENST00000621727, ENSG00000276870, ENSP00000479397

Pharos - Targets

O15496

ZINC - Predictions - Purchasable

PA2GX_HUMAN

HMDB Protein

HMDBP00063

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q01974 ROR2	2	ROR2 [plasma membrane] (R-HSA-197731) ROR2 [clathrin-coated endocytic vesicle membrane] (R-HSA-5140729)	0.556	3
UniProt:O75593 FOXH1	1	FOXH1 [nucleoplasm] (R-HSA-1225914)	0.556	3
UniProt:O14964 HGS	2	HGS [cytosol] (R-HSA-182954) HGS [phagocytic vesicle lumen] (R-HSA-9635660)	0.556	3