Reactome | USP30 [mitochondrial outer membrane]

USP30 [mitochondrial outer membrane]

Stable Identifier

R-HSA-5696931

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial outer membrane

Synonyms

Ubiquitin carboxyl-terminal hydrolase 30 ecNumber evidence="5"3.4.19.12/ecNumber, UBP30_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q70CQ3 USP30

Gene Names

USP30

Chain

chain:1-517

Reference Genes

BioGPS Gene:84749 USP30

COSMIC (genes):USP30 USP30

CTD Gene:84749 USP30

dbSNP Gene:84749 USP30

ENSEMBL:ENSG00000135093 USP30

HGNC:20065 USP30

KEGG:hsa:84749 USP30

Monarch:84749 USP30

NCBI Gene:84749 USP30

OMIM:612492 USP30

UCSC:Q70CQ3 USP30

Reference Transcript

Other Identifiers

11754638_a_at

11754975_a_at

16756597

223602_PM_at

223602_at

227572_PM_at

227572_at

3430893

3430895

3430896

3430897

3430898

3430899

3430900

3430901

3430902

3430903

3430905

3430906

3430909

3430911

3430912

3430913

3430916

3430917

3430918

3430919

3430920

3430921

3430922

3430923

3430924

3430925

60467_at

62600_at

68294_at

7958439

84749

A_14_P109092

A_14_P136691

A_24_P390055

A_24_P87114

GE83473

GE86292

GO:0000422

GO:0000425

GO:0003824

GO:0004197

GO:0004843

GO:0005515

GO:0005634

GO:0005739

GO:0005741

GO:0005778

GO:0005829

GO:0006508

GO:0006914

GO:0007005

GO:0008053

GO:0008234

GO:0016020

GO:0016579

GO:0016787

GO:0031647

GO:0035871

GO:0043226

GO:0044313

GO:0101005

GO:0140096

GO:1901525

HMNXSV003003394

Hs.179520.1.A1_3p_at

ILMN_1741455

PH_hs_0026074

TC12000841.hg

g13436088_3p_at

Participates

as a component of

Other forms of this molecule

USP30 [peroxisomal membrane]

Inferred To

usp30 [mitochondrial outer membrane] (Danio rerio)

usp30 [mitochondrial outer membrane] (Xenopus tropicalis)

Homologues of USP30 [mitochondrial outer membrane] (Schizosaccharomyces pombe)

ubp8 [mitochondrial outer membrane] (Schizosaccharomyces pombe)

USP30 [mitochondrial outer membrane] (Bos taurus)

USP30 [mitochondrial outer membrane] (Caenorhabditis elegans)

USP30 [mitochondrial outer membrane] (Canis familiaris)

USP30 [mitochondrial outer membrane] (Gallus gallus)

USP30 [mitochondrial outer membrane] (Sus scrofa)

Usp30 [mitochondrial outer membrane] (Drosophila melanogaster)

Usp30 [mitochondrial outer membrane] (Mus musculus)

Usp30 [mitochondrial outer membrane] (Rattus norvegicus)

ubp7 [mitochondrial outer membrane] (Schizosaccharomyces pombe)

Cross References

RefSeq

XP_006719716.1, NP_001288104.1, NP_116052.2

ENSEMBL

ENSP00000257548, ENSG00000135093, ENST00000257548

OpenTargets

ENSG00000135093

GeneCards

USP30

HPA

ENSG00000135093-USP30

PRO

Q70CQ3

Pharos - Targets

Q70CQ3

HMDB Protein

HMDBP10131

PDB

5OHN, 5OHP, 5OHK, 8D1T, 8D0A

Interactors (12)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
IntAct:EBI-4399559 UBIQ			0.715	4
UniProt:Q6NTF9-3 Q6NTF93			0.556	3
UniProt:P54253 ATX1			0.556	3
UniProt:O15496 PLA2G10	1	PLA2G10 [extracellular region] (R-HSA-1498793)	0.527	2
UniProt:P30550 GRPR	1	GRPR [plasma membrane] (R-HSA-375363)	0.527	2
UniProt:Q52LD8 RFTN2			0.527	2
UniProt:Q9H813 PACC1			0.527	2
UniProt:Q9NY72 SCN3B	1	SCN3B [plasma membrane] (R-HSA-197921)	0.527	2
UniProt:Q15024 EXOSC7	3	EXOSC7 [nucleolus] (R-HSA-9935779) EXOSC7 [nucleoplasm] (R-HSA-6791543) EXOSC7 [cytosol] (R-HSA-430030)	0.527	2
UniProt:P02746 C1QB	1	C1QB [extracellular region] (R-HSA-173560)	0.527	2
UniProt:Q9H5K3 POMK	1	POMK [endoplasmic reticulum membrane] (R-HSA-8879120)	0.527	2
UniProt:Q6PJG9 LRFN4	1	SALM3 [plasma membrane] (R-HSA-197883)	0.527	2

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