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NAM [cytosol]
Stable Identifier
R-ALL-197277
Type
Chemical Compound [SimpleEntity]
Compartment
cytosol
Synonyms
nicotinamide
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Rattus norvegicus
Sus scrofa
Xenopus tropicalis
Expand all
Cell Cycle (Bos taurus)
Cell Cycle, Mitotic (Bos taurus)
M Phase (Bos taurus)
Mitotic Metaphase and Anaphase (Bos taurus)
Mitotic Anaphase (Bos taurus)
Nuclear Envelope (NE) Reassembly (Bos taurus)
Initiation of Nuclear Envelope (NE) Reformation (Bos taurus)
ANKLE2 is deacetylated by SIRT2 (Bos taurus)
NAM [cytosol]
Metabolism (Bos taurus)
Metabolism of vitamins and cofactors (Bos taurus)
Metabolism of water-soluble vitamins and cofactors (Bos taurus)
Nicotinate metabolism (Bos taurus)
Nicotinamide salvaging (Bos taurus)
NAMPT transfers PRIB to NAM to form NAMN (Bos taurus)
NAM [cytosol]
NNMT transfers CH3 from SAM to NAM to form MNA (Bos taurus)
NAM [cytosol]
PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) (Bos taurus)
NAM [cytosol]
Signal Transduction (Bos taurus)
Intracellular signaling by second messengers (Bos taurus)
PIP3 activates AKT signaling (Bos taurus)
PTEN Regulation (Bos taurus)
Regulation of PTEN stability and activity (Bos taurus)
TNKS and TNKS2 PARylate PTEN (Bos taurus)
NAM [cytosol]
Signaling by WNT (Bos taurus)
TCF dependent signaling in response to WNT (Bos taurus)
Degradation of AXIN (Bos taurus)
Tankyrase ADP-ribosylates AXIN (Bos taurus)
NAM [cytosol]
Metabolism (Caenorhabditis elegans)
Metabolism of vitamins and cofactors (Caenorhabditis elegans)
Metabolism of water-soluble vitamins and cofactors (Caenorhabditis elegans)
Nicotinate metabolism (Caenorhabditis elegans)
Nicotinamide salvaging (Caenorhabditis elegans)
NNMT transfers CH3 from SAM to NAM to form MNA (Caenorhabditis elegans)
NAM [cytosol]
Cell Cycle (Canis familiaris)
Cell Cycle, Mitotic (Canis familiaris)
M Phase (Canis familiaris)
Mitotic Metaphase and Anaphase (Canis familiaris)
Mitotic Anaphase (Canis familiaris)
Nuclear Envelope (NE) Reassembly (Canis familiaris)
Initiation of Nuclear Envelope (NE) Reformation (Canis familiaris)
ANKLE2 is deacetylated by SIRT2 (Canis familiaris)
NAM [cytosol]
Metabolism (Canis familiaris)
Metabolism of vitamins and cofactors (Canis familiaris)
Metabolism of water-soluble vitamins and cofactors (Canis familiaris)
Nicotinate metabolism (Canis familiaris)
Nicotinamide salvaging (Canis familiaris)
NAMPT transfers PRIB to NAM to form NAMN (Canis familiaris)
NAM [cytosol]
NNMT transfers CH3 from SAM to NAM to form MNA (Canis familiaris)
NAM [cytosol]
PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) (Canis familiaris)
NAM [cytosol]
Signal Transduction (Canis familiaris)
Intracellular signaling by second messengers (Canis familiaris)
PIP3 activates AKT signaling (Canis familiaris)
PTEN Regulation (Canis familiaris)
Regulation of PTEN stability and activity (Canis familiaris)
TNKS and TNKS2 PARylate PTEN (Canis familiaris)
NAM [cytosol]
Signaling by WNT (Canis familiaris)
TCF dependent signaling in response to WNT (Canis familiaris)
Degradation of AXIN (Canis familiaris)
Tankyrase ADP-ribosylates AXIN (Canis familiaris)
NAM [cytosol]
Cell Cycle (Danio rerio)
Cell Cycle, Mitotic (Danio rerio)
M Phase (Danio rerio)
Mitotic Metaphase and Anaphase (Danio rerio)
Mitotic Anaphase (Danio rerio)
Nuclear Envelope (NE) Reassembly (Danio rerio)
Initiation of Nuclear Envelope (NE) Reformation (Danio rerio)
ANKLE2 is deacetylated by SIRT2 (Danio rerio)
NAM [cytosol]
Metabolism (Danio rerio)
Metabolism of vitamins and cofactors (Danio rerio)
Metabolism of water-soluble vitamins and cofactors (Danio rerio)
Nicotinate metabolism (Danio rerio)
Nicotinamide salvaging (Danio rerio)
NNMT transfers CH3 from SAM to NAM to form MNA (Danio rerio)
NAM [cytosol]
PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) (Danio rerio)
NAM [cytosol]
Metabolism (Dictyostelium discoideum)
Metabolism of vitamins and cofactors (Dictyostelium discoideum)
Metabolism of water-soluble vitamins and cofactors (Dictyostelium discoideum)
Nicotinate metabolism (Dictyostelium discoideum)
Nicotinamide salvaging (Dictyostelium discoideum)
PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) (Dictyostelium discoideum)
NAM [cytosol]
Cell Cycle (Drosophila melanogaster)
Cell Cycle, Mitotic (Drosophila melanogaster)
M Phase (Drosophila melanogaster)
Mitotic Metaphase and Anaphase (Drosophila melanogaster)
Mitotic Anaphase (Drosophila melanogaster)
Nuclear Envelope (NE) Reassembly (Drosophila melanogaster)
Initiation of Nuclear Envelope (NE) Reformation (Drosophila melanogaster)
ANKLE2 is deacetylated by SIRT2 (Drosophila melanogaster)
NAM [cytosol]
Metabolism (Drosophila melanogaster)
Metabolism of vitamins and cofactors (Drosophila melanogaster)
Metabolism of water-soluble vitamins and cofactors (Drosophila melanogaster)
Nicotinate metabolism (Drosophila melanogaster)
Nicotinamide salvaging (Drosophila melanogaster)
PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) (Drosophila melanogaster)
NAM [cytosol]
Cell Cycle (Gallus gallus)
Cell Cycle, Mitotic (Gallus gallus)
M Phase (Gallus gallus)
Mitotic Metaphase and Anaphase (Gallus gallus)
Mitotic Anaphase (Gallus gallus)
Nuclear Envelope (NE) Reassembly (Gallus gallus)
Initiation of Nuclear Envelope (NE) Reformation (Gallus gallus)
ANKLE2 is deacetylated by SIRT2 (Gallus gallus)
NAM [cytosol]
Metabolism (Gallus gallus)
Metabolism of vitamins and cofactors (Gallus gallus)
Metabolism of water-soluble vitamins and cofactors (Gallus gallus)
Nicotinate metabolism (Gallus gallus)
Nicotinamide salvaging (Gallus gallus)
NAMPT transfers PRIB to NAM to form NAMN (Gallus gallus)
NAM [cytosol]
PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) (Gallus gallus)
NAM [cytosol]
Signal Transduction (Gallus gallus)
Intracellular signaling by second messengers (Gallus gallus)
PIP3 activates AKT signaling (Gallus gallus)
PTEN Regulation (Gallus gallus)
Regulation of PTEN stability and activity (Gallus gallus)
TNKS and TNKS2 PARylate PTEN (Gallus gallus)
NAM [cytosol]
Signaling by WNT (Gallus gallus)
TCF dependent signaling in response to WNT (Gallus gallus)
Degradation of AXIN (Gallus gallus)
Tankyrase ADP-ribosylates AXIN (Gallus gallus)
NAM [cytosol]
Cell Cycle (Homo sapiens)
Cell Cycle, Mitotic (Homo sapiens)
M Phase (Homo sapiens)
Mitotic Metaphase and Anaphase (Homo sapiens)
Mitotic Anaphase (Homo sapiens)
Nuclear Envelope (NE) Reassembly (Homo sapiens)
Initiation of Nuclear Envelope (NE) Reformation (Homo sapiens)
ANKLE2 is deacetylated by SIRT2 (Homo sapiens)
NAM [cytosol]
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Bacterial Infection Pathways (Homo sapiens)
Infection with Mycobacterium tuberculosis (Homo sapiens)
Escape of Mtb from the phagocyte (Homo sapiens)
Phagocyte cell death caused by cytosolic Mtb (Homo sapiens)
CpnT hydrolyses NAD+ (Homo sapiens)
NAM [cytosol]
Uptake and actions of bacterial toxins (Homo sapiens)
Uptake and function of diphtheria toxin (Homo sapiens)
DT fragment A ADP-ribosylates target cell EEF (Homo sapiens)
NAM [cytosol]
Viral Infection Pathways (Homo sapiens)
SARS-CoV Infections (Homo sapiens)
SARS-CoV-1 Infection (Homo sapiens)
Translation of Structural Proteins (Homo sapiens)
Maturation of nucleoprotein (Homo sapiens)
Nucleoprotein is ADP-ribosylated (Homo sapiens)
NAM [cytosol]
SARS-CoV-2 Infection (Homo sapiens)
Late SARS-CoV-2 Infection Events (Homo sapiens)
Translation of Structural Proteins (Homo sapiens)
Maturation of nucleoprotein (Homo sapiens)
Nucleoprotein is ADP-ribosylated (Homo sapiens)
NAM [cytosol]
Metabolism (Homo sapiens)
Metabolism of amino acids and derivatives (Homo sapiens)
Selenoamino acid metabolism (Homo sapiens)
Metabolism of ingested SeMet, Sec, MeSec into H2Se (Homo sapiens)
AdoSeMet is converted to AdeSeHCys by MetTrans(1) (Homo sapiens)
Hist,NAM,Gly [cytosol]
NAM [cytosol]
Metabolism of vitamins and cofactors (Homo sapiens)
Metabolism of water-soluble vitamins and cofactors (Homo sapiens)
Nicotinate metabolism (Homo sapiens)
Nicotinamide salvaging (Homo sapiens)
NAMPT transfers PRIB to NAM to form NAMN (Homo sapiens)
NAM [cytosol]
NNMT transfers CH3 from SAM to NAM to form MNA (Homo sapiens)
NAM [cytosol]
PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) (Homo sapiens)
NAM [cytosol]
Signal Transduction (Homo sapiens)
Intracellular signaling by second messengers (Homo sapiens)
PIP3 activates AKT signaling (Homo sapiens)
PTEN Regulation (Homo sapiens)
Regulation of PTEN stability and activity (Homo sapiens)
TNKS and TNKS2 PARylate PTEN (Homo sapiens)
NAM [cytosol]
Signaling by WNT (Homo sapiens)
TCF dependent signaling in response to WNT (Homo sapiens)
Degradation of AXIN (Homo sapiens)
Tankyrase ADP-ribosylates AXIN (Homo sapiens)
NAM [cytosol]
Cell Cycle (Mus musculus)
Cell Cycle, Mitotic (Mus musculus)
M Phase (Mus musculus)
Mitotic Metaphase and Anaphase (Mus musculus)
Mitotic Anaphase (Mus musculus)
Nuclear Envelope (NE) Reassembly (Mus musculus)
Initiation of Nuclear Envelope (NE) Reformation (Mus musculus)
ANKLE2 is deacetylated by SIRT2 (Mus musculus)
NAM [cytosol]
Metabolism (Mus musculus)
Metabolism of vitamins and cofactors (Mus musculus)
Metabolism of water-soluble vitamins and cofactors (Mus musculus)
Nicotinate metabolism (Mus musculus)
Nicotinamide salvaging (Mus musculus)
NAMPT transfers PRIB to NAM to form NAMN (Mus musculus)
NAM [cytosol]
NNMT transfers CH3 from SAM to NAM to form MNA (Mus musculus)
NAM [cytosol]
PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) (Mus musculus)
NAM [cytosol]
Signal Transduction (Mus musculus)
Intracellular signaling by second messengers (Mus musculus)
PIP3 activates AKT signaling (Mus musculus)
PTEN Regulation (Mus musculus)
Regulation of PTEN stability and activity (Mus musculus)
TNKS and TNKS2 PARylate PTEN (Mus musculus)
NAM [cytosol]
Signaling by WNT (Mus musculus)
TCF dependent signaling in response to WNT (Mus musculus)
Degradation of AXIN (Mus musculus)
Tankyrase ADP-ribosylates AXIN (Mus musculus)
NAM [cytosol]
Cell Cycle (Rattus norvegicus)
Cell Cycle, Mitotic (Rattus norvegicus)
M Phase (Rattus norvegicus)
Mitotic Metaphase and Anaphase (Rattus norvegicus)
Mitotic Anaphase (Rattus norvegicus)
Nuclear Envelope (NE) Reassembly (Rattus norvegicus)
Initiation of Nuclear Envelope (NE) Reformation (Rattus norvegicus)
ANKLE2 is deacetylated by SIRT2 (Rattus norvegicus)
NAM [cytosol]
Metabolism (Rattus norvegicus)
Metabolism of vitamins and cofactors (Rattus norvegicus)
Metabolism of water-soluble vitamins and cofactors (Rattus norvegicus)
Nicotinate metabolism (Rattus norvegicus)
Nicotinamide salvaging (Rattus norvegicus)
NAMPT transfers PRIB to NAM to form NAMN (Rattus norvegicus)
NAM [cytosol]
NNMT transfers CH3 from SAM to NAM to form MNA (Rattus norvegicus)
NAM [cytosol]
PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) (Rattus norvegicus)
NAM [cytosol]
Signal Transduction (Rattus norvegicus)
Intracellular signaling by second messengers (Rattus norvegicus)
PIP3 activates AKT signaling (Rattus norvegicus)
PTEN Regulation (Rattus norvegicus)
Regulation of PTEN stability and activity (Rattus norvegicus)
TNKS and TNKS2 PARylate PTEN (Rattus norvegicus)
NAM [cytosol]
Signaling by WNT (Rattus norvegicus)
TCF dependent signaling in response to WNT (Rattus norvegicus)
Degradation of AXIN (Rattus norvegicus)
Tankyrase ADP-ribosylates AXIN (Rattus norvegicus)
NAM [cytosol]
Cell Cycle (Sus scrofa)
Cell Cycle, Mitotic (Sus scrofa)
M Phase (Sus scrofa)
Mitotic Metaphase and Anaphase (Sus scrofa)
Mitotic Anaphase (Sus scrofa)
Nuclear Envelope (NE) Reassembly (Sus scrofa)
Initiation of Nuclear Envelope (NE) Reformation (Sus scrofa)
ANKLE2 is deacetylated by SIRT2 (Sus scrofa)
NAM [cytosol]
Metabolism (Sus scrofa)
Metabolism of vitamins and cofactors (Sus scrofa)
Metabolism of water-soluble vitamins and cofactors (Sus scrofa)
Nicotinate metabolism (Sus scrofa)
Nicotinamide salvaging (Sus scrofa)
NAMPT transfers PRIB to NAM to form NAMN (Sus scrofa)
NAM [cytosol]
NNMT transfers CH3 from SAM to NAM to form MNA (Sus scrofa)
NAM [cytosol]
PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) (Sus scrofa)
NAM [cytosol]
Signal Transduction (Sus scrofa)
Intracellular signaling by second messengers (Sus scrofa)
PIP3 activates AKT signaling (Sus scrofa)
PTEN Regulation (Sus scrofa)
Regulation of PTEN stability and activity (Sus scrofa)
TNKS and TNKS2 PARylate PTEN (Sus scrofa)
NAM [cytosol]
Signaling by WNT (Sus scrofa)
TCF dependent signaling in response to WNT (Sus scrofa)
Degradation of AXIN (Sus scrofa)
Tankyrase ADP-ribosylates AXIN (Sus scrofa)
NAM [cytosol]
Metabolism (Xenopus tropicalis)
Metabolism of vitamins and cofactors (Xenopus tropicalis)
Metabolism of water-soluble vitamins and cofactors (Xenopus tropicalis)
Nicotinate metabolism (Xenopus tropicalis)
Nicotinamide salvaging (Xenopus tropicalis)
NAMPT transfers PRIB to NAM to form NAMN (Xenopus tropicalis)
NAM [cytosol]
NNMT transfers CH3 from SAM to NAM to form MNA (Xenopus tropicalis)
NAM [cytosol]
PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) (Xenopus tropicalis)
NAM [cytosol]
External Reference Information
External Reference
nicotinamide [ChEBI:17154]
Participates
as an input of
NNMT transfers CH3 from SAM to NAM to form MNA (Caenorhabditis elegans)
NNMT transfers CH3 from SAM to NAM to form MNA (Xenopus tropicalis)
NNMT transfers CH3 from SAM to NAM to form MNA (Danio rerio)
NNMT transfers CH3 from SAM to NAM to form MNA (Sus scrofa)
NNMT transfers CH3 from SAM to NAM to form MNA (Bos taurus)
NNMT transfers CH3 from SAM to NAM to form MNA (Canis familiaris)
NNMT transfers CH3 from SAM to NAM to form MNA (Rattus norvegicus)
NNMT transfers CH3 from SAM to NAM to form MNA (Mus musculus)
NAMPT transfers PRIB to NAM to form NAMN (Homo sapiens)
NAMPT transfers PRIB to NAM to form NAMN (Mus musculus)
NAMPT transfers PRIB to NAM to form NAMN (Rattus norvegicus)
NAMPT transfers PRIB to NAM to form NAMN (Canis familiaris)
NAMPT transfers PRIB to NAM to form NAMN (Bos taurus)
NAMPT transfers PRIB to NAM to form NAMN (Sus scrofa)
NAMPT transfers PRIB to NAM to form NAMN (Xenopus tropicalis)
NAMPT transfers PRIB to NAM to form NAMN (Gallus gallus)
NNMT transfers CH3 from SAM to NAM to form MNA (Homo sapiens)
as an output of
CpnT hydrolyses NAD+ (Homo sapiens)
DT fragment A ADP-ribosylates target cell EEF (Homo sapiens)
Nucleoprotein is ADP-ribosylated (Homo sapiens)
Nucleoprotein is ADP-ribosylated (Homo sapiens)
TNKS and TNKS2 PARylate PTEN (Homo sapiens)
TNKS and TNKS2 PARylate PTEN (Mus musculus)
TNKS and TNKS2 PARylate PTEN (Rattus norvegicus)
TNKS and TNKS2 PARylate PTEN (Canis familiaris)
TNKS and TNKS2 PARylate PTEN (Bos taurus)
TNKS and TNKS2 PARylate PTEN (Sus scrofa)
TNKS and TNKS2 PARylate PTEN (Gallus gallus)
ANKLE2 is deacetylated by SIRT2 (Bos taurus)
ANKLE2 is deacetylated by SIRT2 (Homo sapiens)
ANKLE2 is deacetylated by SIRT2 (Mus musculus)
ANKLE2 is deacetylated by SIRT2 (Rattus norvegicus)
ANKLE2 is deacetylated by SIRT2 (Canis familiaris)
ANKLE2 is deacetylated by SIRT2 (Sus scrofa)
ANKLE2 is deacetylated by SIRT2 (Danio rerio)
ANKLE2 is deacetylated by SIRT2 (Gallus gallus)
ANKLE2 is deacetylated by SIRT2 (Drosophila melanogaster)
Tankyrase ADP-ribosylates AXIN (Homo sapiens)
Tankyrase ADP-ribosylates AXIN (Mus musculus)
Tankyrase ADP-ribosylates AXIN (Rattus norvegicus)
Tankyrase ADP-ribosylates AXIN (Canis familiaris)
Tankyrase ADP-ribosylates AXIN (Bos taurus)
Tankyrase ADP-ribosylates AXIN (Sus scrofa)
Tankyrase ADP-ribosylates AXIN (Gallus gallus)
PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) (Homo sapiens)
PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) (Mus musculus)
PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) (Rattus norvegicus)
PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) (Canis familiaris)
PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) (Bos taurus)
PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) (Sus scrofa)
PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) (Danio rerio)
PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) (Xenopus tropicalis)
PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) (Gallus gallus)
PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) (Drosophila melanogaster)
PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) (Dictyostelium discoideum)
as a member of
Hist,NAM,Gly [cytosol]
Other forms of this molecule
NAM [mitochondrial intermembrane space]
NAM [extracellular region]
NAM [mitochondrial matrix]
NAM [nucleoplasm]
Cross References
COMPOUND
C00153
HMDB Metabolite
HMDB0001406
ZINC
000000005878
© 2024
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![NAM [cytosol] icon](/icon/R-ICO-013078.svg){kind=icon}
