Reactome | AGT(25-32) binds to AGTR2

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AGT(25-32) binds to AGTR2 Show undefined attributes

authored	[InstanceEdit:375275] Jassal, Bijay, 2008-08-21
category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:9615349] Jassal, Bijay, 2018-08-02
dbId	9615348
displayName	AGT(25-32) binds to AGTR2
edited	[InstanceEdit:375493] D'Eustachio, P, 2008-09-01 11:58:31
eventOf	[Pathway:R-HSA-375276] Peptide ligand-binding receptors - Homo sapiens
followingEvent	[Reaction:R-HSA-749448] Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq - Homo sapiens [Reaction:R-HSA-749456] Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-374187] AGT(25-32) [extracellular region] [EntityWithAccessionedSequence:R-HSA-374130] AGTR2 [plasma membrane]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:374212] Molecular cloning and expression of the gene encoding human angiotensin II type 2 receptor
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	AGT(25-32) binds to AGTR2
orthologousEvent	[Reaction:R-GGA-9615348] AGT(25-32) binds to AGTR2 - Gallus gallus [Reaction:R-DRE-9615348] AGT(25-32) binds to AGTR2 - Danio rerio [Reaction:R-SSC-9615348] AGT(25-32) binds to AGTR2 - Sus scrofa [Reaction:R-BTA-9615348] AGT(25-32) binds to AGTR2 - Bos taurus [Reaction:R-CFA-9615348] AGT(25-32) binds to AGTR2 - Canis familiaris [Reaction:R-RNO-9615348] AGT(25-32) binds to AGTR2 - Rattus norvegicus [Reaction:R-MMU-9615348] AGT(25-32) binds to AGTR2 - Mus musculus
output	[Complex:R-HSA-389873] AGTR2:AGT(25-32) [plasma membrane]
precedingEvent	[Reaction:R-HSA-2022405] ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) - Homo sapiens [Reaction:R-HSA-2065355] Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) - Homo sapiens
releaseDate	2008-09-30
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:375494] Bockaert, J, 2008-09-01 12:04:13
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9615348
summation	[Summation:374239] The cardiovascular and other actions of the vasoconstricting...

Referrals

(hasEvent)	[Pathway:R-HSA-375276] Peptide ligand-binding receptors
(precedingEvent)	[Reaction:R-HSA-749448] Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq [Reaction:R-HSA-749456] Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi