Reactome | Aspartate and asparagine metabolism

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Aspartate and asparagine metabolism Show undefined attributes

authored	[InstanceEdit:8963714] Jassal, Bijay, 2017-02-10
created	[InstanceEdit:8963690] Jassal, Bijay, 2017-02-10
dbId	8963693
deleted	[Deleted:9640344] Deletion of instance: 70614
displayName	Aspartate and asparagine metabolism
doi	10.3180/R-HSA-8963693.2
edited	[InstanceEdit:8982686] D'Eustachio, Peter, 2017-03-21
eventOf	[Pathway:R-HSA-71291] Metabolism of amino acids and derivatives - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:9910493] L-amino acid metabolic process
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-HSA-372448] SLC25A12,13 exchange L-Glu and L-Asp - Homo sapiens [Reaction:R-HSA-70592] PXLP-K259-GOT1 transaminates 2-OG and L-Asp - Homo sapiens [Reaction:R-HSA-70596] GOT2 dimer transaminates L-Asp - Homo sapiens [Reaction:R-HSA-70581] oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] - Homo sapiens [Reaction:R-HSA-70599] aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] - Homo sapiens [Reaction:R-HSA-6797627] ASPG hydrolyses L-Asn to L-Asp - Homo sapiens [Reaction:R-HSA-5691507] ASPA deacetylates NAASP to acetate and L-aspartate - Homo sapiens [BlackBoxEvent:R-HSA-8954513] NAASP translocates from mitochondrial matrix to cytosol - Homo sapiens [Reaction:R-HSA-8954468] NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAASP - Homo sapiens [Reaction:R-HSA-6787757] PXLP-K333-GADL1 decarboxylates acidic AAs - Homo sapiens [Reaction:R-HSA-5693783] NAALADases hydrolyse NAAG - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2022-12-07
literatureReference	[LiteratureReference:9644857] Amino acid metabolism in man [LiteratureReference:9644820] Energy metabolism in feasting and fasting
maxDepth	2
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	Aspartate and asparagine metabolism
orthologousEvent	[Pathway:R-RNO-8963693] Aspartate and asparagine metabolism - Rattus norvegicus [Pathway:R-PFA-8963693] Aspartate and asparagine metabolism - Plasmodium falciparum [Pathway:R-SCE-8963693] Aspartate and asparagine metabolism - Saccharomyces cerevisiae [Pathway:R-SPO-8963693] Aspartate and asparagine metabolism - Schizosaccharomyces pombe [Pathway:R-DDI-8963693] Aspartate and asparagine metabolism - Dictyostelium discoideum [Pathway:R-CEL-8963693] Aspartate and asparagine metabolism - Caenorhabditis elegans [Pathway:R-DME-8963693] Aspartate and asparagine metabolism - Drosophila melanogaster [Pathway:R-GGA-8963693] Aspartate and asparagine metabolism - Gallus gallus [Pathway:R-XTR-8963693] Aspartate and asparagine metabolism - Xenopus tropicalis [Pathway:R-DRE-8963693] Aspartate and asparagine metabolism - Danio rerio [Pathway:R-SSC-8963693] Aspartate and asparagine metabolism - Sus scrofa [Pathway:R-BTA-8963693] Aspartate and asparagine metabolism - Bos taurus [Pathway:R-CFA-8963693] Aspartate and asparagine metabolism - Canis familiaris [Pathway:R-MMU-8963693] Aspartate and asparagine metabolism - Mus musculus
releaseDate	2004-07-06
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-8963693
summation	[Summation:9644855] These reactions mediate the synthesis of aspartate and aspar...
updateTrackers	[UpdateTracker:9846981] Update Tracker - [Pathway:8963693] Aspartate and asparagine metabolism - v82:[updateContainedRLE] [UpdateTracker:9863979] Update Tracker - [Pathway:8963693] Aspartate and asparagine metabolism - v88:[updateContainedRLE] [UpdateTracker:9846868] Update Tracker - [Pathway:8963693] Aspartate and asparagine metabolism - v83:[updateContainedRLE]

Referrals

(updatedInstance)	[UpdateTracker:9846981] Update Tracker - [Pathway:8963693] Aspartate and asparagine metabolism - v82:[updateContainedRLE] [UpdateTracker:9863979] Update Tracker - [Pathway:8963693] Aspartate and asparagine metabolism - v88:[updateContainedRLE] [UpdateTracker:9846868] Update Tracker - [Pathway:8963693] Aspartate and asparagine metabolism - v83:[updateContainedRLE]
(replacementInstances)	[Deleted:9640344] Deletion of instance: 70614
(hasEvent)	[Pathway:R-HSA-71291] Metabolism of amino acids and derivatives

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