aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS]

catalystActivity
catalystActivityReference [CatalystActivityReference:9643819] asparagine synthase (glutamine-hydrolyzing) activity of ASNS dimer [cytosol] Expression of human asparagine synthetase in Escherichia coli
category transition
compartment
crossReference
dbId 70599
displayName aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS]
eventOf
followingEvent
input
isInDisease false
isInferred false
literatureReference
maxDepth 1
modified [InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name
  • aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS]
  • ATP + H2O + L-aspartate + L-glutamine => AMP + diphosphate + H(+) + L-asparagine + L-glutamate
negativePrecedingEvent
orthologousEvent
output
precedingEvent
previousReviewStatus [ReviewStatus:9821385] four stars
releaseDate 2004-07-06
reviewStatus [ReviewStatus:9821382] five stars
reviewed
schemaClass Reaction
species
stId R-HSA-70599
summation
updateTrackers
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