Reactome | FasL/ CD95L signaling

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FasL/ CD95L signaling Show undefined attributes

authored	[InstanceEdit:140480] Gillespie, ME, 2004-08-18 21:05:31
created	[InstanceEdit:110071] Tschopp, J�rg, 2004-01-28
crossReference	[DatabaseIdentifier:12819567] BioModels Database:BIOMD0000000525 [DatabaseIdentifier:12819569] BioModels Database:BIOMD0000000523 [DatabaseIdentifier:12819571] BioModels Database:BIOMD0000000524 [DatabaseIdentifier:12819573] BioModels Database:BIOMD0000000243 [DatabaseIdentifier:12819459] BioModels Database:BIOMD0000000407 [DatabaseIdentifier:12819695] BioModels Database:BIOMD0000000661 [DatabaseIdentifier:12819575] BioModels Database:BIOMD0000000526
dbId	75157
displayName	FasL/ CD95L signaling
edited	[InstanceEdit:165085] Gillespie, ME, 0000-00-00 00:00:00
eventOf	[Pathway:R-HSA-73887] Death Receptor Signaling - Homo sapiens
figure	[Figure:141234] /figures/FAS_Top.jpg
goBiologicalProcess	[GO_BiologicalProcess:2133497] apoptotic signaling pathway
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-HSA-75244] FASL binds FAS Receptor - Homo sapiens [Reaction:R-HSA-71050] Trimerization of the FASL:FAS receptor complex - Homo sapiens [Reaction:R-HSA-83650] FasL:Fas binds FADD - Homo sapiens [Reaction:R-HSA-83586] FASL:FAS Receptor Trimer:FADD complex binds pro-Caspase-8 - Homo sapiens [Reaction:R-HSA-141310] FASL:FAS Receptor Trimer:FADD complex binds procaspase-10 - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2014-12-08
literatureReference	[LiteratureReference:139960] The biochemistry of apoptosis.
maxDepth	2
modified	[InstanceEdit:12819426] Weiser, Joel, 2026-02-23
name	FasL/ CD95L signaling
orthologousEvent	[Pathway:R-MMU-75157] FasL/ CD95L signaling - Mus musculus [Pathway:R-GGA-75157] FasL/ CD95L signaling - Gallus gallus [Pathway:R-XTR-75157] FasL/ CD95L signaling - Xenopus tropicalis [Pathway:R-SSC-75157] FasL/ CD95L signaling - Sus scrofa [Pathway:R-BTA-75157] FasL/ CD95L signaling - Bos taurus [Pathway:R-CFA-75157] FasL/ CD95L signaling - Canis familiaris [Pathway:R-RNO-75157] FasL/ CD95L signaling - Rattus norvegicus
releaseDate	2004-10-27
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:165094] Vaux, D, 0000-00-00 00:00:00 [InstanceEdit:3597630] Pop, Cristina, Salvesen, Guy S., 2013-05-22
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-75157
summation	[Summation:140481] The Fas family of cell surface receptors initiate the apotot...
updateTrackers	[UpdateTracker:9786355] Update Tracker - [Pathway:75157] FasL/ CD95L signaling - v49:[updateContainedRLE] [UpdateTracker:9785644] Update Tracker - [Pathway:75157] FasL/ CD95L signaling - v51:[updateContainedRLE] [UpdateTracker:9788209] Update Tracker - [Pathway:75157] FasL/ CD95L signaling - v43:[updateContainedRLE] [UpdateTracker:9787978] Update Tracker - [Pathway:75157] FasL/ CD95L signaling - v44:[updateContainedRLE]

Referrals

(updatedInstance)	[UpdateTracker:9786355] Update Tracker - [Pathway:75157] FasL/ CD95L signaling - v49:[updateContainedRLE] [UpdateTracker:9785644] Update Tracker - [Pathway:75157] FasL/ CD95L signaling - v51:[updateContainedRLE] [UpdateTracker:9788209] Update Tracker - [Pathway:75157] FasL/ CD95L signaling - v43:[updateContainedRLE] [UpdateTracker:9787978] Update Tracker - [Pathway:75157] FasL/ CD95L signaling - v44:[updateContainedRLE]
(hasEncapsulatedEvent)	[Pathway:R-HSA-5633008] TP53 Regulates Transcription of Cell Death Genes [Pathway:R-HSA-5357769] Caspase activation via extrinsic apoptotic signalling pathway
(hasEvent)	[Pathway:R-HSA-73887] Death Receptor Signaling

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