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Entries
Met-tRNAi binds to eIF2:GTP to form the ternary complex
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category
binding
compartment
[Compartment:70101] cytosol
dbId
72669
displayName
Met-tRNAi binds to eIF2:GTP to form the ternary complex
eventOf
[Pathway:R-HSA-72695] Formation of the ternary complex, and subsequently, the 43S complex - Homo sapiens
followingEvent
[Reaction:R-HSA-72691] Formation of the 43S pre-initiation complex - Homo sapiens
input
[Complex:R-HSA-72531] eIF2:GTP [cytosol]
[OtherEntity:R-ALL-72393] Met-tRNAi [cytosol]
isInDisease
false
isInferred
false
literatureReference
[LiteratureReference:72665] Binding of MET-TRNAf and GTP to homogeneous initiation factor MP
modified
[InstanceEdit:10931649] Wright, Adam, 2024-03-08
name
Met-tRNAi binds to eIF2:GTP to form the ternary complex
orthologousEvent
[Reaction:R-MMU-72669] Met-tRNAi binds to eIF2:GTP to form the ternary complex - Mus musculus
[Reaction:R-PFA-72669] Met-tRNAi binds to eIF2:GTP to form the ternary complex - Plasmodium falciparum
[Reaction:R-SCE-72669] Met-tRNAi binds to eIF2:GTP to form the ternary complex - Saccharomyces cerevisiae
[Reaction:R-SPO-72669] Met-tRNAi binds to eIF2:GTP to form the ternary complex - Schizosaccharomyces pombe
[Reaction:R-DDI-72669] Met-tRNAi binds to eIF2:GTP to form the ternary complex - Dictyostelium discoideum
[Reaction:R-CEL-72669] Met-tRNAi binds to eIF2:GTP to form the ternary complex - Caenorhabditis elegans
[Reaction:R-DME-72669] Met-tRNAi binds to eIF2:GTP to form the ternary complex - Drosophila melanogaster
[Reaction:R-GGA-72669] Met-tRNAi binds to eIF2:GTP to form the ternary complex - Gallus gallus
[Reaction:R-XTR-72669] Met-tRNAi binds to eIF2:GTP to form the ternary complex - Xenopus tropicalis
[Reaction:R-DRE-72669] Met-tRNAi binds to eIF2:GTP to form the ternary complex - Danio rerio
[Reaction:R-SSC-72669] Met-tRNAi binds to eIF2:GTP to form the ternary complex - Sus scrofa
[Reaction:R-BTA-72669] Met-tRNAi binds to eIF2:GTP to form the ternary complex - Bos taurus
[Reaction:R-CFA-72669] Met-tRNAi binds to eIF2:GTP to form the ternary complex - Canis familiaris
[Reaction:R-RNO-72669] Met-tRNAi binds to eIF2:GTP to form the ternary complex - Rattus norvegicus
output
[Complex:R-HSA-72532] ternary complex [cytosol]
precedingEvent
[Reaction:R-HSA-379994] methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate - Homo sapiens
[Reaction:R-HSA-72663] De novo formation of eIF2:GTP - Homo sapiens
[Reaction:R-HSA-72722] eIF2 activation - Homo sapiens
regulatedBy
[Requirement:R-HSA-72779] Requirement by 'GTP [cytosol]'
releaseDate
2004-07-06
reviewStatus
[ReviewStatus:9821382] five stars
schemaClass
Reaction
species
[Species:48887] Homo sapiens
stId
R-HSA-72669
summation
[Summation:72742] The ternary complex forms upon binding of the initiator meth...
Referrals
(hasEvent)
[Pathway:R-HSA-72695] Formation of the ternary complex, and subsequently, the 43S complex
(precedingEvent)
[Reaction:R-HSA-72691] Formation of the 43S pre-initiation complex
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