Reactome | Met-tRNAi binds to eIF2:GTP to form the ternary complex

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Met-tRNAi binds to eIF2:GTP to form the ternary complex Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10336109
displayName	Met-tRNAi binds to eIF2:GTP to form the ternary complex
eventOf	[Pathway:R-BTA-72695] Formation of the ternary complex, and subsequently, the 43S complex - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-BTA-72691] Formation of the 43S pre-initiation complex - Bos taurus
inferredFrom	[Reaction:R-HSA-72669] Met-tRNAi binds to eIF2:GTP to form the ternary complex - Homo sapiens
input	[Complex:R-BTA-72531] eIF2:GTP [cytosol] [OtherEntity:R-ALL-72393] Met-tRNAi [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Met-tRNAi binds to eIF2:GTP to form the ternary complex
output	[Complex:R-BTA-72532] ternary complex [cytosol]
precedingEvent	[Reaction:R-BTA-72663] De novo formation of eIF2:GTP - Bos taurus [Reaction:R-BTA-72722] eIF2 activation - Bos taurus
regulatedBy	[Requirement:R-HSA-72779] Requirement by 'GTP [cytosol]'
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-72669
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-72695] Formation of the ternary complex, and subsequently, the 43S complex
(precedingEvent)	[Reaction:R-BTA-72691] Formation of the 43S pre-initiation complex
(inferredTo)	[Reaction:R-HSA-72669] Met-tRNAi binds to eIF2:GTP to form the ternary complex

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