Reactome | Formation of the 43S pre-initiation complex

Schema > Reaction > Entries

Formation of the 43S pre-initiation complex Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol
dbId	72691
displayName	Formation of the 43S pre-initiation complex
eventOf	[Pathway:R-HSA-72695] Formation of the ternary complex, and subsequently, the 43S complex - Homo sapiens
input	[Complex:R-HSA-72570] 40S:eIF3:eIF1A [cytosol] [Complex:R-HSA-72532] ternary complex [cytosol]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:72677] Binding and release of radiolabeled eukaryotic initiation factors 2 and 3 during 80 S initiation complex formation [LiteratureReference:72650] The mechanism of action of protein synthesis initiation factors from rabbit reticulocytes [LiteratureReference:72652] Initiation of mammalian protein synthesis. II. The assembly of the initiation complex with purified initiation factors [Book:72692] 9783642751394 New insights into an old problem: ternary complex (Met-tRNAf.eIF.GTP) formation in animal cells. Post-Transcriptional Control of Gene Expression McCarthy, John E G
maxDepth	1
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	Formation of the 43S pre-initiation complex
orthologousEvent	[Reaction:R-RNO-72691] Formation of the 43S pre-initiation complex - Rattus norvegicus [Reaction:R-PFA-72691] Formation of the 43S pre-initiation complex - Plasmodium falciparum [Reaction:R-SCE-72691] Formation of the 43S pre-initiation complex - Saccharomyces cerevisiae [Reaction:R-SPO-72691] Formation of the 43S pre-initiation complex - Schizosaccharomyces pombe [Reaction:R-DDI-72691] Formation of the 43S pre-initiation complex - Dictyostelium discoideum [Reaction:R-CEL-72691] Formation of the 43S pre-initiation complex - Caenorhabditis elegans [Reaction:R-DME-72691] Formation of the 43S pre-initiation complex - Drosophila melanogaster [Reaction:R-GGA-72691] Formation of the 43S pre-initiation complex - Gallus gallus [Reaction:R-XTR-72691] Formation of the 43S pre-initiation complex - Xenopus tropicalis [Reaction:R-DRE-72691] Formation of the 43S pre-initiation complex - Danio rerio [Reaction:R-SSC-72691] Formation of the 43S pre-initiation complex - Sus scrofa [Reaction:R-BTA-72691] Formation of the 43S pre-initiation complex - Bos taurus [Reaction:R-CFA-72691] Formation of the 43S pre-initiation complex - Canis familiaris [Reaction:R-MMU-72691] Formation of the 43S pre-initiation complex - Mus musculus
output	[Complex:R-HSA-72571] 43S complex [cytosol]
precedingEvent	[Reaction:R-HSA-72669] Met-tRNAi binds to eIF2:GTP to form the ternary complex - Homo sapiens
releaseDate	2004-07-06
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-72691
summation	[Summation:72694] The ternary complex (Met-tRNAi:eIF2:GTP) binds to the comple...

Referrals

(hasEvent)

[Pathway:R-HSA-72695] Formation of the ternary complex, and subsequently, the 43S complex

Cite Us!