Reactome | p-S166,S188-MDM2 [nucleoplasm]

Schema > EntityWithAccessionedSequence > Entries

p-S166,S188-MDM2 [nucleoplasm] Show undefined attributes

candidateOf	[CandidateSet:R-HSA-6792895] p-T218,S166,S188-MDM2, p-S166,S188-MDM2 [nucleoplasm] - Homo sapiens
compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-HSA-6804939] p-S166,S188-MDM2:p-S403-MDM4 [nucleoplasm] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-6804955] ATM phosphorylates MDM2 - Homo sapiens [Reaction:R-HSA-6793661] (CDK1,CDK2):CCNA phosphorylates MDM2 at T218 - Homo sapiens [Reaction:R-HSA-6804741] MDM2 forms homo- or heterodimers - Homo sapiens [Reaction:R-HSA-6804741] MDM2 forms homo- or heterodimers - Homo sapiens
created	[InstanceEdit:6793664] Orlic-Milacic, Marija, 2015-09-03
dbId	6793669
displayName	p-S166,S188-MDM2 [nucleoplasm]
endCoordinate	491
hasModifiedResidue	[ModifiedResidue:2399939] O-phospho-L-serine at 166 [ModifiedResidue:2399935] O-phospho-L-serine at 188
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-6793669] phospho-p-S166,S188-MDM2 [nucleoplasm] - Mus musculus [EntityWithAccessionedSequence:R-RNO-6793669] phospho-p-S166,S188-MDM2 [nucleoplasm] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-6793669] phospho-p-S166,S188-MDM2 [nucleoplasm] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-6793669] phospho-MDM2 [nucleoplasm] - Bos taurus [EntityWithAccessionedSequence:R-SSC-6793669] phospho-MDM2 [nucleoplasm] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-6793669] phospho-mdm2 [nucleoplasm] - Danio rerio [EntityWithAccessionedSequence:R-XTR-6793669] phospho-mdm2 [nucleoplasm] - Xenopus tropicalis [EntityWithAccessionedSequence:R-XTR-6793669-2] phospho-p-S166,S188-MDM2 [nucleoplasm] - Xenopus tropicalis [DefinedSet:R-XTR-6793669-3] Homologues of p-S166,S188-MDM2 [nucleoplasm] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-6793669] phospho-MDM2 [nucleoplasm] - Gallus gallus
maxDepth	1
memberOf	[DefinedSet:R-HSA-6804750] p-S166,S188-MDM2,MDM4 [nucleoplasm] - Homo sapiens
name	p-S166,S188-MDM2 p-S166,188-MDM2 p-MDM2 Phospho-MDM2
producedByEvent	[Reaction:R-HSA-6793666] MDM2 translocates to the nucleus - Homo sapiens
referenceEntity	[ReferenceGeneProduct:uniprot:Q00987] UniProt:Q00987 MDM2
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-6793669
startCoordinate	1

Referrals

(input)	[Reaction:R-HSA-6804955] ATM phosphorylates MDM2 [Reaction:R-HSA-6793661] (CDK1,CDK2):CCNA phosphorylates MDM2 at T218 [Reaction:R-HSA-6804741] MDM2 forms homo- or heterodimers
(hasCandidate)	[CandidateSet:R-HSA-6792895] p-T218,S166,S188-MDM2, p-S166,S188-MDM2 [nucleoplasm]
(hasComponent)	[Complex:R-HSA-6804939] p-S166,S188-MDM2:p-S403-MDM4 [nucleoplasm] [Complex:R-HSA-6804936] p-S166,S188-MDM2:p-S346,S367,S403-MDM4 [nucleoplasm] [Complex:R-HSA-6804932] p-S166,S188-MDM2:MDM4 [nucleoplasm] [Complex:R-HSA-6804933] p-S166,S188-MDM2 dimer [nucleoplasm]
(output)	[Reaction:R-HSA-6793666] MDM2 translocates to the nucleus
(hasMember)	[DefinedSet:R-HSA-6804750] p-S166,S188-MDM2,MDM4 [nucleoplasm]