Reactome | p-S166,S188-MDM2:p-S346,S367,S403-MDM4 [nucleoplasm]

Schema > Complex > Entries

candidateOf	[CandidateSet:R-HSA-6805030] p-S166,S188-MDM2:(p-S166,S188-MDM2,p-S346,S367,S403-MDM4) [nucleoplasm] - Homo sapiens
catalystActivities	[CatalystActivity:6804946] ubiquitin protein ligase activity of p-S166,S188-MDM2:p-S346,S367,S403-MDM4 [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
consumedByEvent	[Reaction:R-HSA-6804724] MDM2 ubiquitinates phosphorylated MDM4 - Homo sapiens
created	[InstanceEdit:6804930] Orlic-Milacic, Marija, 2015-10-15
dbId	6804936
displayName	p-S166,S188-MDM2:p-S346,S367,S403-MDM4 [nucleoplasm]
hasComponent	[EntityWithAccessionedSequence:R-HSA-6793669] p-S166,S188-MDM2 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-349441] p-S346,S367,S403-MDM4 [nucleoplasm]
inDisease	false
inferredTo	[Complex:R-MMU-6804936] p-S166,S188-MDM2:p-S346,S367,S403-MDM4 [nucleoplasm] - Mus musculus [Complex:R-RNO-6804936] p-S166,S188-MDM2:p-S346,S367,S403-MDM4 [nucleoplasm] - Rattus norvegicus [Complex:R-CFA-6804936] p-S166,S188-MDM2:p-S346,S367,S403-MDM4 [nucleoplasm] - Canis familiaris [Complex:R-DRE-6804936] p-S166,S188-MDM2:p-S346,S367,S403-MDM4 [nucleoplasm] - Danio rerio [Complex:R-GGA-6804936] p-S166,S188-MDM2:p-S346,S367,S403-MDM4 [nucleoplasm] - Gallus gallus
isChimeric	false
maxDepth	2
name	p-S166,S188-MDM2:p-S346,S367,S403-MDM4
producedByEvent	[Reaction:R-HSA-5689972] USP2 deubiquitinates MDM2,MDM4 - Homo sapiens [Reaction:R-HSA-349426] Phosphorylation of MDM4 by CHEK2 - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-6804936

(output)	[Reaction:R-HSA-5689972] USP2 deubiquitinates MDM2,MDM4 [Reaction:R-HSA-349426] Phosphorylation of MDM4 by CHEK2
(hasCandidate)	[CandidateSet:R-HSA-6805030] p-S166,S188-MDM2:(p-S166,S188-MDM2,p-S346,S367,S403-MDM4) [nucleoplasm]
(input)	[Reaction:R-HSA-6804724] MDM2 ubiquitinates phosphorylated MDM4
(physicalEntity)	[CatalystActivity:6804946] ubiquitin protein ligase activity of p-S166,S188-MDM2:p-S346,S367,S403-MDM4 [nucleoplasm]