Reactome | TRAF2 [cytosol]

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TRAF2 [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-9693918] TRADD:TRAF2:RIPK1 variant:FADD [cytosol] - Homo sapiens [Complex:R-HSA-9693918] TRADD:TRAF2:RIPK1 variant:FADD [cytosol] - Homo sapiens [Complex:R-HSA-9693918] TRADD:TRAF2:RIPK1 variant:FADD [cytosol] - Homo sapiens [Complex:R-HSA-5668475] TRAF1:TRAF2:K63polyUb-cIAP1,2 [cytosol] - Homo sapiens [Complex:R-HSA-9816109] TNF-?:TNFR1:TRADD:polyUb-RIPK1:TRAF2:MIB2 [plasma membrane] - Homo sapiens [Complex:R-HSA-9816109] TNF-?:TNFR1:TRADD:polyUb-RIPK1:TRAF2:MIB2 [plasma membrane] - Homo sapiens [Complex:R-HSA-9816109] TNF-?:TNFR1:TRADD:polyUb-RIPK1:TRAF2:MIB2 [plasma membrane] - Homo sapiens [Complex:R-HSA-9818791] TNF?:TNFR1:TRADD:K63,Met1polyUb, p-S25-RIPK1:BIRC2/3:p-S-CHUK:p-S-IKBKB:IKBKG [plasma membrane] - Homo sapiens [Complex:R-HSA-9818791] TNF?:TNFR1:TRADD:K63,Met1polyUb, p-S25-RIPK1:BIRC2/3:p-S-CHUK:p-S-IKBKB:IKBKG [plasma membrane] - Homo sapiens [Complex:R-HSA-9818791] TNF?:TNFR1:TRADD:K63,Met1polyUb, p-S25-RIPK1:BIRC2/3:p-S-CHUK:p-S-IKBKB:IKBKG [plasma membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-83656] TNF:TNFR1 binds TRADD, TRAF2 and RIPK1 - Homo sapiens [Reaction:R-HSA-83656] TNF:TNFR1 binds TRADD, TRAF2 and RIPK1 - Homo sapiens [Reaction:R-HSA-83656] TNF:TNFR1 binds TRADD, TRAF2 and RIPK1 - Homo sapiens [Reaction:R-HSA-5634221] TRAF1 binds TRAF2 within TNFR1 signaling complex - Homo sapiens [Reaction:R-HSA-5634221] TRAF1 binds TRAF2 within TNFR1 signaling complex - Homo sapiens
dbId	66370
displayName	TRAF2 [cytosol]
endCoordinate	501
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-66370] Traf2 [cytosol] - Mus musculus [EntityWithAccessionedSequence:R-RNO-66370] Traf2 [cytosol] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-66370] TRAF2 [cytosol] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-66370] TRAF2 [cytosol] - Bos taurus [EntityWithAccessionedSequence:R-SSC-66370] TRAF2 [cytosol] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-66370] traf2b [cytosol] - Danio rerio [EntityWithAccessionedSequence:R-DRE-66370-2] traf2a [cytosol] - Danio rerio [DefinedSet:R-DRE-66370-3] Homologues of TRAF2 [cytosol] - Danio rerio [EntityWithAccessionedSequence:R-XTR-66370] traf2 [cytosol] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-66370] TRAF2 [cytosol] - Gallus gallus [EntityWithAccessionedSequence:R-DME-66370] Traf-like [cytosol] - Drosophila melanogaster [EntityWithAccessionedSequence:R-DDI-66370] zfaA [cytosol] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-66370-2] TRAF2 [cytosol] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-66370-3] TRAF2 [cytosol] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-66370-4] TRAF2 [cytosol] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-66370-5] TRAF2 [cytosol] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-66370-6] TRAF2 [cytosol] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-66370-7] TRAF2 [cytosol] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-66370-8] TRAF2 [cytosol] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-66370-9] TRAF2 [cytosol] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-66370-10] TRAF2 [cytosol] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-66370-11] TRAF2 [cytosol] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-66370-12] TRAF2 [cytosol] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-66370-13] TRAF2 [cytosol] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-66370-14] TRAF2 [cytosol] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-66370-15] TRAF2 [cytosol] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-66370-16] TRAF2 [cytosol] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-66370-17] TRAF2 [cytosol] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-66370-18] TRAF2 [cytosol] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-66370-19] TRAF2 [cytosol] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-66370-20] TRAF2 [cytosol] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-66370-21] TRAF2 [cytosol] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-66370-22] TRAF2 [cytosol] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-66370-23] TRAF2 [cytosol] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-66370-24] TRAF2 [cytosol] - Dictyostelium discoideum [DefinedSet:R-DDI-66370-25] Homologues of TRAF2 [cytosol] - Dictyostelium discoideum
maxDepth	1
memberOf	[DefinedSet:R-HSA-918188] TRAF2, TRAF6 [cytosol] - Homo sapiens [DefinedSet:R-HSA-6782832] TRAF2,TRAF6,IKBKG,RIPK1 [cytosol] - Homo sapiens
modified	[InstanceEdit:3132750] Wu, G, 2013-02-13
name	TRAF2 TNF receptor associated factor 2 Tumor necrosis factor type 2 receptor associated protein 3
referenceEntity	[ReferenceGeneProduct:uniprot:Q12933] UniProt:Q12933 TRAF2
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-66370
startCoordinate	2
updateTrackers	[UpdateTracker:9869469] Update Tracker - [EntityWithAccessionedSequence:66370] TRAF2 [cytosol] - v33:[addName] [UpdateTracker:9879851] Update Tracker - [EntityWithAccessionedSequence:66370] TRAF2 [cytosol] - v44:[modifyEndCoordinate, modifyStartCoordinate]

Referrals

(hasComponent)	[Complex:R-HSA-9693918] TRADD:TRAF2:RIPK1 variant:FADD [cytosol] [Complex:R-HSA-5668475] TRAF1:TRAF2:K63polyUb-cIAP1,2 [cytosol] [Complex:R-HSA-5668489] TRAF2:cIAP1,2 [cytosol] [Complex:R-HSA-9818791] TNF?:TNFR1:TRADD:K63,Met1polyUb, p-S25-RIPK1:BIRC2/3:p-S-CHUK:p-S-IKBKB:IKBKG [plasma membrane] [Complex:R-HSA-5634184] TNFalpha:TNFR1:TRADD:TRAF2:TRAF1:RIPK1 [plasma membrane] [Complex:R-HSA-9817409] TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD:TBK1,IKBKE [plasma membrane] [Complex:R-HSA-9793688] TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC [plasma membrane] [Complex:R-HSA-9817363] TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD [plasma membrane] [Complex:R-HSA-140935] TRAF2:TRADD:RIPK1 [cytosol] [Complex:R-HSA-9819071] TRAF2:TRADD:p-S357-RIPK1 [cytosol] [Complex:R-HSA-9815499] TRAF2:TRADD:p-S320-RIPK1 [cytosol] [Complex:R-HSA-140946] TNF-?:TNFR1:TRADD:RIPK1:TRAF2 [plasma membrane] [Complex:R-HSA-9817389] TNF-alpha:TNFR1:TRADD:p-T189,K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD:TBK1,IKBKE [plasma membrane] [Complex:R-HSA-9816109] TNF-?:TNFR1:TRADD:polyUb-RIPK1:TRAF2:MIB2 [plasma membrane] [Complex:R-HSA-5357809] TRAF2:TRADD:RIPK1(325-671):FADD [cytosol] [Complex:R-HSA-5357756] TNF-?:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane]
(input)	[Reaction:R-HSA-5634221] TRAF1 binds TRAF2 within TNFR1 signaling complex [Reaction:R-HSA-83656] TNF:TNFR1 binds TRADD, TRAF2 and RIPK1
(hasMember)	[DefinedSet:R-HSA-6782832] TRAF2,TRAF6,IKBKG,RIPK1 [cytosol] [DefinedSet:R-HSA-918188] TRAF2, TRAF6 [cytosol]
(updatedInstance)	[UpdateTracker:9869469] Update Tracker - [EntityWithAccessionedSequence:66370] TRAF2 [cytosol] - v33:[addName] [UpdateTracker:9879851] Update Tracker - [EntityWithAccessionedSequence:66370] TRAF2 [cytosol] - v44:[modifyEndCoordinate, modifyStartCoordinate]

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