Reactome | TRAF2:TRADD:p-S357-RIPK1 [cytosol]

Schema > Complex > Entries

compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9819079] Shamovsky, Veronica, 2022-11-01
dbId	9819071
displayName	TRAF2:TRADD:p-S357-RIPK1 [cytosol]
goCellularComponent	[GO_CellularComponent:161217] death-inducing signaling complex
hasComponent	[EntityWithAccessionedSequence:R-HSA-9819116] p-S357-RIPK1 [cytosol] 3 × [EntityWithAccessionedSequence:R-HSA-66376] TRADD [cytosol] 3 × [EntityWithAccessionedSequence:R-HSA-66370] TRAF2 [cytosol]
inDisease	false
inferredTo	[Complex:R-MMU-9819071] TRAF2:TRADD:p-S357-RIPK1 [cytosol] - Mus musculus [Complex:R-RNO-9819071] TRAF2:TRADD:p-S357-RIPK1 [cytosol] - Rattus norvegicus [Complex:R-CFA-9819071] TRAF2:TRADD:p-S357-RIPK1 [cytosol] - Canis familiaris [Complex:R-BTA-9819071] TRAF2:TRADD:p-S357-RIPK1 [cytosol] - Bos taurus [Complex:R-SSC-9819071] TRAF2:TRADD:p-S357-RIPK1 [cytosol] - Sus scrofa [Complex:R-DRE-9819071] TRAF2:TRADD:p-S357-RIPK1 [cytosol] - Danio rerio [Complex:R-GGA-9819071] TRAF2:TRADD:p-S357-RIPK1 [cytosol] - Gallus gallus
maxDepth	2
modified	[InstanceEdit:9983308] Weiser, Joel, 2026-02-22
name	TRAF2:TRADD:p-S357-RIPK1
negativelyRegulates	[NegativeRegulation:9819131] Negative regulation by 'TRAF2:TRADD:p-S357-RIPK1 [cytosol]'
producedByEvent	[Reaction:R-HSA-9819106] ULK1 phosphorylates RIPK1 at S357 - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-9819071

(output)	[Reaction:R-HSA-9819106] ULK1 phosphorylates RIPK1 at S357
(regulator)	[NegativeRegulation:9819131] Negative regulation by 'TRAF2:TRADD:p-S357-RIPK1 [cytosol]'