Reactome | Traf2 [cytosol]

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Traf2 [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-RNO-5357809] TRAF2:TRADD:RIPK1(325-671):FADD [cytosol] - Rattus norvegicus [Complex:R-RNO-5357809] TRAF2:TRADD:RIPK1(325-671):FADD [cytosol] - Rattus norvegicus [Complex:R-RNO-5357809] TRAF2:TRADD:RIPK1(325-671):FADD [cytosol] - Rattus norvegicus [Complex:R-RNO-5668489] TRAF2:cIAP1,2 [cytosol] - Rattus norvegicus [Complex:R-RNO-9816109] TNF-?:TNFR1:TRADD:polyUb-RIPK1:TRAF2:MIB2 [plasma membrane] - Rattus norvegicus [Complex:R-RNO-9816109] TNF-?:TNFR1:TRADD:polyUb-RIPK1:TRAF2:MIB2 [plasma membrane] - Rattus norvegicus [Complex:R-RNO-9816109] TNF-?:TNFR1:TRADD:polyUb-RIPK1:TRAF2:MIB2 [plasma membrane] - Rattus norvegicus [Complex:R-RNO-9818791] TNF?:TNFR1:TRADD:K63,Met1polyUb, p-S25-RIPK1:BIRC2/3:p-S-CHUK:p-S-IKBKB:IKBKG [plasma membrane] - Rattus norvegicus [Complex:R-RNO-9818791] TNF?:TNFR1:TRADD:K63,Met1polyUb, p-S25-RIPK1:BIRC2/3:p-S-CHUK:p-S-IKBKB:IKBKG [plasma membrane] - Rattus norvegicus [Complex:R-RNO-9818791] TNF?:TNFR1:TRADD:K63,Met1polyUb, p-S25-RIPK1:BIRC2/3:p-S-CHUK:p-S-IKBKB:IKBKG [plasma membrane] - Rattus norvegicus
consumedByEvent	[Reaction:R-RNO-83656] TNF:TNFR1 binds TRADD, TRAF2 and RIPK1 - Rattus norvegicus [Reaction:R-RNO-83656] TNF:TNFR1 binds TRADD, TRAF2 and RIPK1 - Rattus norvegicus [Reaction:R-RNO-83656] TNF:TNFR1 binds TRADD, TRAF2 and RIPK1 - Rattus norvegicus [Reaction:R-RNO-5634221] TRAF1 binds TRAF2 within TNFR1 signaling complex - Rattus norvegicus [Reaction:R-RNO-5634221] TRAF1 binds TRAF2 within TNFR1 signaling complex - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10110600
displayName	Traf2 [cytosol]
endCoordinate	501
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-66370] TRAF2 [cytosol] - Homo sapiens
maxDepth	1
memberOf	[DefinedSet:R-RNO-918188] TRAF2, TRAF6 [cytosol] - Rattus norvegicus [DefinedSet:R-RNO-6782832] TRAF2,TRAF6,IKBKG,RIPK1 [cytosol] - Rattus norvegicus
name	Traf2 TRAF2 B5DFH7
referenceEntity	[ReferenceGeneProduct:uniprot:B5DFH7] UniProt:B5DFH7
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48895] Rattus norvegicus
stId	R-RNO-66370
startCoordinate	2

Referrals

(hasMember)	[DefinedSet:R-RNO-6782832] TRAF2,TRAF6,IKBKG,RIPK1 [cytosol] [DefinedSet:R-RNO-918188] TRAF2, TRAF6 [cytosol]
(hasComponent)	[Complex:R-RNO-5668489] TRAF2:cIAP1,2 [cytosol] [Complex:R-RNO-5668475] TRAF1:TRAF2:K63polyUb-cIAP1,2 [cytosol] [Complex:R-RNO-9818791] TNF?:TNFR1:TRADD:K63,Met1polyUb, p-S25-RIPK1:BIRC2/3:p-S-CHUK:p-S-IKBKB:IKBKG [plasma membrane] [Complex:R-RNO-5634184] TNFalpha:TNFR1:TRADD:TRAF2:TRAF1:RIPK1 [plasma membrane] [Complex:R-RNO-9817409] TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD:TBK1,IKBKE [plasma membrane] [Complex:R-RNO-9793688] TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC [plasma membrane] [Complex:R-RNO-9817363] TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD [plasma membrane] [Complex:R-RNO-5357756] TNF-?:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] [Complex:R-RNO-5357809] TRAF2:TRADD:RIPK1(325-671):FADD [cytosol] [Complex:R-RNO-9816109] TNF-?:TNFR1:TRADD:polyUb-RIPK1:TRAF2:MIB2 [plasma membrane] [Complex:R-RNO-9817389] TNF-alpha:TNFR1:TRADD:p-T189,K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD:TBK1,IKBKE [plasma membrane] [Complex:R-RNO-140946] TNF-?:TNFR1:TRADD:RIPK1:TRAF2 [plasma membrane] [Complex:R-RNO-9815499] TRAF2:TRADD:p-S320-RIPK1 [cytosol] [Complex:R-RNO-9819071] TRAF2:TRADD:p-S357-RIPK1 [cytosol] [Complex:R-RNO-140935] TRAF2:TRADD:RIPK1 [cytosol]
(input)	[Reaction:R-RNO-5634221] TRAF1 binds TRAF2 within TNFR1 signaling complex [Reaction:R-RNO-83656] TNF:TNFR1 binds TRADD, TRAF2 and RIPK1
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-66370] TRAF2 [cytosol]

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