Reactome | SRF [nucleoplasm]

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SRF [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-HSA-9769687] SRF:NPAS4 gene [nucleoplasm] - Homo sapiens [Complex:R-HSA-9031611] p-S133-CREB1:MEF2D:SRF:ARC gene [nucleoplasm] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-9612509] SGK phosphorylates SRF - Homo sapiens [Reaction:R-HSA-9768832] SRF binds NPAS4 gene promoter - Homo sapiens [Reaction:R-HSA-9625479] SRF and ELK1 bind the FOS gene - Homo sapiens [Reaction:R-HSA-9612076] p-4S, T366 ELK1:SRF bind EGR1 and EGR2 gene promoters - Homo sapiens [Reaction:R-HSA-5665998] MKL1 binds SRF - Homo sapiens [Reaction:R-HSA-9031610] p-S133 CREB1, MEF2D and SRF bind the ARC gene - Homo sapiens
created	[InstanceEdit:5665997] Orlic-Milacic, Marija, 2015-01-20
dbId	5666000
displayName	SRF [nucleoplasm]
endCoordinate	508
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-5666000] Srf [nucleoplasm] - Mus musculus [EntityWithAccessionedSequence:R-RNO-5666000] Srf [nucleoplasm] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-5666000] SRF [nucleoplasm] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-5666000] SRF [nucleoplasm] - Bos taurus [EntityWithAccessionedSequence:R-SSC-5666000] SRF [nucleoplasm] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-5666000] srfa [nucleoplasm] - Danio rerio [EntityWithAccessionedSequence:R-DME-5666000] bs [nucleoplasm] - Drosophila melanogaster [EntityWithAccessionedSequence:R-CEL-5666000] unc-120 [nucleoplasm] - Caenorhabditis elegans [EntityWithAccessionedSequence:R-DDI-5666000] srfA [nucleoplasm] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-SPO-5666000] map1 [nucleoplasm] - Schizosaccharomyces pombe [EntityWithAccessionedSequence:R-SCE-5666000] MCM1 [nucleoplasm] - Saccharomyces cerevisiae
maxDepth	1
name	SRF Serum response factor
producedByEvent	[BlackBoxEvent:R-HSA-9735505] Expression of SRF in cardiogenesis - Homo sapiens
referenceEntity	[ReferenceGeneProduct:uniprot:P11831] UniProt:P11831 SRF
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-5666000
startCoordinate	1

Referrals

(output)	[BlackBoxEvent:R-HSA-9735505] Expression of SRF in cardiogenesis
(activeUnit)	[PositiveGeneExpressionRegulation:9769698] Positive gene expression regulation by 'SRF:NPAS4 gene [nucleoplasm]' [PositiveGeneExpressionRegulation:9620411] Positive gene expression regulation by 'p-S133-CREB1:MEF2D:SRF:ARC gene [nucleoplasm]'
(hasComponent)	[Complex:R-HSA-9769687] SRF:NPAS4 gene [nucleoplasm] [Complex:R-HSA-9625460] FOS gene:SRF:p-4S,T336 ELK1 [nucleoplasm] [Complex:R-HSA-9612054] p-4S, T336 ELK1:SRF [nucleoplasm] [Complex:R-HSA-9031611] p-S133-CREB1:MEF2D:SRF:ARC gene [nucleoplasm] [Complex:R-HSA-5666002] SRF:MKL1 [nucleoplasm]
(input)	[Reaction:R-HSA-9768832] SRF binds NPAS4 gene promoter [Reaction:R-HSA-9625479] SRF and ELK1 bind the FOS gene [Reaction:R-HSA-9612076] p-4S, T366 ELK1:SRF bind EGR1 and EGR2 gene promoters [Reaction:R-HSA-9031610] p-S133 CREB1, MEF2D and SRF bind the ARC gene [Reaction:R-HSA-9612509] SGK phosphorylates SRF [Reaction:R-HSA-5665998] MKL1 binds SRF

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