Reactome | TBXT [nucleoplasm]

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-HSA-9756683] EOMES:TBXT:NANOG gene [nucleoplasm] - Homo sapiens [Complex:R-HSA-9733794] EOMES:WDR5:KAT2A:TBXT:MESP1 gene [nucleoplasm] - Homo sapiens [Complex:R-HSA-9823834] p-2S-SMAD2,3:SMAD4:FOXA2:TBXT:GATA6:GATA4 gene [nucleoplasm] - Homo sapiens [Complex:R-HSA-9823744] TCF7L2:CTNNB1:EOMES:TBXT:MIXL1:p-2S-SMAD2,3:SMAD4:FOXA2:GATA4:GATA6,SOX17 gene [nucleoplasm] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-9733781] EOMES, WDR5, KAT2A, and TBXT bind the MESP1 gene - Homo sapiens [Reaction:R-HSA-9756671] EOMES and TBXT bind the NANOG gene - Homo sapiens [Reaction:R-HSA-9756670] EOMES and TBXT bind the POU5F1 (OCT4) gene - Homo sapiens [Reaction:R-HSA-9756661] EOMES and TBXT bind the SOX2 gene - Homo sapiens [Reaction:R-HSA-9756666] EOMES and TBXT (T, Brachyury) bind the SNAI1 gene - Homo sapiens [Reaction:R-HSA-9823836] SMAD2,3, FOXA2, TBXT, and GATA6 bind the GATA4 gene - Homo sapiens [Reaction:R-HSA-9823958] EOMES, TBXT (T BRACHYURY), GATA6, and SMAD2,3 bind the FOXA2 gene - Homo sapiens [Reaction:R-HSA-9796225] TEAD2,TEAD4:YAP1, TBXT, FOXH1, and SMAD2,3 bind the FOXA2 gene - Homo sapiens [Reaction:R-HSA-9824472] TCF7L2:CTNNB1, EOMES, TBXT, MIXL1, SMAD2,3, FOXA2, GATA4, and GATA6 bind the SOX17 gene - Homo sapiens
created	[InstanceEdit:452990] May, B, 2010-01-15
dbId	452976
displayName	TBXT [nucleoplasm]
endCoordinate	435
inDisease	false
maxDepth	1
modified	[InstanceEdit:9750924] May, Bruce, 2021-08-17
name	TBXT T T (BRACHYURY) Brachyury protein BRAC_HUMAN
positivelyRegulates	[PositiveGeneExpressionRegulation:9793412] Positive gene expression regulation by 'TBXT [nucleoplasm]'
producedByEvent	[BlackBoxEvent:R-HSA-452331] Expression of TBXT (T, Brachyury) in the primitive streak - Homo sapiens
referenceEntity	[ReferenceGeneProduct:uniprot:O15178] UniProt:O15178 TBXT
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-452976
startCoordinate	1

(hasComponent)	[Complex:R-HSA-9733794] EOMES:WDR5:KAT2A:TBXT:MESP1 gene [nucleoplasm] [Complex:R-HSA-9756683] EOMES:TBXT:NANOG gene [nucleoplasm] [Complex:R-HSA-9756663] EOMES:TBXT:POU5F1 gene [nucleoplasm] [Complex:R-HSA-9756679] EOMES:TBXT:SOX2 gene [nucleoplasm] [Complex:R-HSA-9823834] p-2S-SMAD2,3:SMAD4:FOXA2:TBXT:GATA6:GATA4 gene [nucleoplasm] [Complex:R-HSA-9823744] TCF7L2:CTNNB1:EOMES:TBXT:MIXL1:p-2S-SMAD2,3:SMAD4:FOXA2:GATA4:GATA6,SOX17 gene [nucleoplasm] [Complex:R-HSA-9823963] EOMES:TBXT:GATA6:p-2S-SMAD2,3:SMAD4:FOXA2 gene [nucleoplasm] [Complex:R-HSA-9796240] TEAD2,TEAD4:YAP1:FOXH1:p-SMAD2,3:TBXT:FOXA2 gene [nucleoplasm] [Complex:R-HSA-9756662] EOMES:TBXT:SNAI1 gene [nucleoplasm]
(input)	[Reaction:R-HSA-9733781] EOMES, WDR5, KAT2A, and TBXT bind the MESP1 gene [Reaction:R-HSA-9756671] EOMES and TBXT bind the NANOG gene [Reaction:R-HSA-9756670] EOMES and TBXT bind the POU5F1 (OCT4) gene [Reaction:R-HSA-9756661] EOMES and TBXT bind the SOX2 gene [Reaction:R-HSA-9823836] SMAD2,3, FOXA2, TBXT, and GATA6 bind the GATA4 gene [Reaction:R-HSA-9824472] TCF7L2:CTNNB1, EOMES, TBXT, MIXL1, SMAD2,3, FOXA2, GATA4, and GATA6 bind the SOX17 gene [Reaction:R-HSA-9823958] EOMES, TBXT (T BRACHYURY), GATA6, and SMAD2,3 bind the FOXA2 gene [Reaction:R-HSA-9796225] TEAD2,TEAD4:YAP1, TBXT, FOXH1, and SMAD2,3 bind the FOXA2 gene [Reaction:R-HSA-9756666] EOMES and TBXT (T, Brachyury) bind the SNAI1 gene
(regulator)	[PositiveGeneExpressionRegulation:9793412] Positive gene expression regulation by 'TBXT [nucleoplasm]'
(output)	[BlackBoxEvent:R-HSA-452331] Expression of TBXT (T, Brachyury) in the primitive streak

TBXT [nucleoplasm] Show undefined attributes

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