Reactome | Detachment of WASP/WAVE

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Detachment of WASP/WAVE Show undefined attributes

authored	[InstanceEdit:434636] Jupe, S, 2009-09-02
category	dissociation
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:2197699] Garapati, P V, 2012-04-13
dbId	2197690
displayName	Detachment of WASP/WAVE
edited	[InstanceEdit:2029483] Garapati, P V, 2012-01-04 [InstanceEdit:5671747] Orlic-Milacic, Marija, 2015-02-02
eventOf	[Pathway:R-HSA-5663213] RHO GTPases Activate WASPs and WAVEs - Homo sapiens [Pathway:R-HSA-2029482] Regulation of actin dynamics for phagocytic cup formation - Homo sapiens [Pathway:R-HSA-9664422] FCGR3A-mediated phagocytosis - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-2029473] Branching and elongation of mother and daughter filaments - Homo sapiens
input	[Complex:R-HSA-2029140] Mother filament:branching complex [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:2197706] Arp2/3 ATP hydrolysis: to branch or to debranch? [LiteratureReference:2028852] ATP hydrolysis on actin-related protein 2/3 complex causes debranching of dendritic actin arrays
maxDepth	1
modified	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
name	Detachment of WASP/WAVE
orthologousEvent	[Reaction:R-MMU-2197690] Detachment of WASP/WAVE - Mus musculus [Reaction:R-DDI-2197690] Detachment of WASP/WAVE - Dictyostelium discoideum [Reaction:R-CEL-2197690] Detachment of WASP/WAVE - Caenorhabditis elegans [Reaction:R-DME-2197690] Detachment of WASP/WAVE - Drosophila melanogaster [Reaction:R-GGA-2197690] Detachment of WASP/WAVE - Gallus gallus [Reaction:R-XTR-2197690] Detachment of WASP/WAVE - Xenopus tropicalis [Reaction:R-DRE-2197690] Detachment of WASP/WAVE - Danio rerio [Reaction:R-SSC-2197690] Detachment of WASP/WAVE - Sus scrofa [Reaction:R-BTA-2197690] Detachment of WASP/WAVE - Bos taurus [Reaction:R-CFA-2197690] Detachment of WASP/WAVE - Canis familiaris [Reaction:R-RNO-2197690] Detachment of WASP/WAVE - Rattus norvegicus
output	[Complex:R-HSA-2197686] Mother filament:ARP2/3:actin:ADP [cytosol] [DefinedSet:R-HSA-2197675] WAVE2, WASP, N-WASP [plasma membrane]
precedingEvent	[Reaction:R-HSA-2029466] (WASPs, WAVE):G-actin:ARP2/3 binds F-actin - Homo sapiens
releaseDate	2013-03-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:2248842] Rosales, C, 2012-05-14 [InstanceEdit:5668821] Rivero Crespo, Francisco, 2014-12-26
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-2197690
summation	[Summation:2197708] After incorporation at the branch, the actin bound to VCA do...
updateTrackers	[UpdateTracker:9785269] Update Tracker - [Reaction:2197690] Detachment of WASP/WAVE - v52:[modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9785269] Update Tracker - [Reaction:2197690] Detachment of WASP/WAVE - v52:[modifyText]
(hasEvent)	[Pathway:R-HSA-9664422] FCGR3A-mediated phagocytosis [Pathway:R-HSA-5663213] RHO GTPases Activate WASPs and WAVEs [Pathway:R-HSA-2029482] Regulation of actin dynamics for phagocytic cup formation
(precedingEvent)	[BlackBoxEvent:R-HSA-2029473] Branching and elongation of mother and daughter filaments

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