Reactome | Detachment of WASP/WAVE

Schema > Reaction > Entries

Detachment of WASP/WAVE Show undefined attributes

category	dissociation
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:10818988] Wright, Adam, 2024-03-08
dbId	10841328
displayName	Detachment of WASP/WAVE
eventOf	[Pathway:R-DDI-5663213] RHO GTPases Activate WASPs and WAVEs - Dictyostelium discoideum [Pathway:R-DDI-2029482] Regulation of actin dynamics for phagocytic cup formation - Dictyostelium discoideum
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[BlackBoxEvent:R-DDI-2029473] Branching and elongation of mother and daughter filaments - Dictyostelium discoideum
inferredFrom	[Reaction:R-HSA-2197690] Detachment of WASP/WAVE - Homo sapiens
input	[Complex:R-DDI-2029140] Mother filament:branching complex [cytosol]
isInDisease	false
isInferred	true
name	Detachment of WASP/WAVE
output	[Complex:R-DDI-2197686] Mother filament:ARP2/3:actin:ADP [cytosol] [DefinedSet:R-DDI-2197675] WAVE2, WASP, N-WASP [plasma membrane]
precedingEvent	[Reaction:R-DDI-2029466] (WASPs, WAVE):G-actin:ARP2/3 binds F-actin - Dictyostelium discoideum
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:170941] Dictyostelium discoideum
stId	R-DDI-2197690
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DDI-5663213] RHO GTPases Activate WASPs and WAVEs [Pathway:R-DDI-2029482] Regulation of actin dynamics for phagocytic cup formation
(precedingEvent)	[BlackBoxEvent:R-DDI-2029473] Branching and elongation of mother and daughter filaments
(inferredTo)	[Reaction:R-HSA-2197690] Detachment of WASP/WAVE