Reactome | Branching and elongation of mother and daughter filaments

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Branching and elongation of mother and daughter filaments Show undefined attributes

authored	[InstanceEdit:434636] Jupe, S, 2009-09-02
category	uncertain
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:2029472] Garapati, P V, 2012-01-04
dbId	2029473
displayName	Branching and elongation of mother and daughter filaments
edited	[InstanceEdit:2029483] Garapati, P V, 2012-01-04 [InstanceEdit:5671747] Orlic-Milacic, Marija, 2015-02-02
eventOf	[Pathway:R-HSA-5663213] RHO GTPases Activate WASPs and WAVEs - Homo sapiens [Pathway:R-HSA-2029482] Regulation of actin dynamics for phagocytic cup formation - Homo sapiens [Pathway:R-HSA-9664422] FCGR3A-mediated phagocytosis - Homo sapiens
followingEvent	[Reaction:R-HSA-1861595] Extension of pseudopodia by myosin-X in a PI3K dependent manner - Homo sapiens
input	3 × [Complex:R-HSA-201857] G-actin [cytosol] [Complex:R-HSA-2197686] Mother filament:ARP2/3:actin:ADP [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:2028835] Regulation of actin assembly associated with protrusion and adhesion in cell migration [LiteratureReference:418750] Signalling to actin assembly via the WASP (Wiskott-Aldrich syndrome protein)-family proteins and the Arp2/3 complex
maxDepth	1
modified	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
name	Branching and elongation of mother and daughter filaments
orthologousEvent	[BlackBoxEvent:R-MMU-2029473] Branching and elongation of mother and daughter filaments - Mus musculus [BlackBoxEvent:R-SCE-2029473] Branching and elongation of mother and daughter filaments - Saccharomyces cerevisiae [BlackBoxEvent:R-SPO-2029473] Branching and elongation of mother and daughter filaments - Schizosaccharomyces pombe [BlackBoxEvent:R-DDI-2029473] Branching and elongation of mother and daughter filaments - Dictyostelium discoideum [BlackBoxEvent:R-CEL-2029473] Branching and elongation of mother and daughter filaments - Caenorhabditis elegans [BlackBoxEvent:R-DME-2029473] Branching and elongation of mother and daughter filaments - Drosophila melanogaster [BlackBoxEvent:R-GGA-2029473] Branching and elongation of mother and daughter filaments - Gallus gallus [BlackBoxEvent:R-XTR-2029473] Branching and elongation of mother and daughter filaments - Xenopus tropicalis [BlackBoxEvent:R-DRE-2029473] Branching and elongation of mother and daughter filaments - Danio rerio [BlackBoxEvent:R-SSC-2029473] Branching and elongation of mother and daughter filaments - Sus scrofa [BlackBoxEvent:R-BTA-2029473] Branching and elongation of mother and daughter filaments - Bos taurus [BlackBoxEvent:R-CFA-2029473] Branching and elongation of mother and daughter filaments - Canis familiaris [BlackBoxEvent:R-RNO-2029473] Branching and elongation of mother and daughter filaments - Rattus norvegicus
output	[Complex:R-HSA-1861699] Mother filament:branching complex:daughter filament [cytosol]
precedingEvent	[Reaction:R-HSA-2197690] Detachment of WASP/WAVE - Homo sapiens
releaseDate	2013-03-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:2248842] Rosales, C, 2012-05-14 [InstanceEdit:5668821] Rivero Crespo, Francisco, 2014-12-26
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-2029473
summation	[Summation:2028808] ATP bound G-actin monomers are added to the fast growing bar...
updateTrackers	[UpdateTracker:9781640] Update Tracker - [BlackBoxEvent:2029473] Branching and elongation of mother and daughter filaments - v60:[modifyText, removeOutput] [UpdateTracker:9785264] Update Tracker - [BlackBoxEvent:2029473] Branching and elongation of mother and daughter filaments - v52:[modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9781640] Update Tracker - [BlackBoxEvent:2029473] Branching and elongation of mother and daughter filaments - v60:[modifyText, removeOutput] [UpdateTracker:9785264] Update Tracker - [BlackBoxEvent:2029473] Branching and elongation of mother and daughter filaments - v52:[modifyText]
(hasEvent)	[Pathway:R-HSA-9664422] FCGR3A-mediated phagocytosis [Pathway:R-HSA-5663213] RHO GTPases Activate WASPs and WAVEs [Pathway:R-HSA-2029482] Regulation of actin dynamics for phagocytic cup formation
(precedingEvent)	[Reaction:R-HSA-1861595] Extension of pseudopodia by myosin-X in a PI3K dependent manner

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