Reactome | COPII-mediated vesicle transport

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COPII-mediated vesicle transport Show undefined attributes

authored	[InstanceEdit:199976] Gillespie, ME, 2007-07-13 20:42:29
created	[InstanceEdit:203980] Gillespie, ME, 2007-11-21 20:48:45
crossReference	[DatabaseIdentifier:12819645] BioModels Database:BIOMD0000000336 [DatabaseIdentifier:12819555] BioModels Database:BIOMD0000000335 [DatabaseIdentifier:12819557] BioModels Database:BIOMD0000000951
dbId	204005
displayName	COPII-mediated vesicle transport
edited	[InstanceEdit:203980] Gillespie, ME, 2007-11-21 20:48:45
eventOf	[Pathway:R-HSA-199977] ER to Golgi Anterograde Transport - Homo sapiens
figure	[Figure:204043] /figures/COPIIoverview.jpg
goBiologicalProcess	[GO_BiologicalProcess:78933] COPII vesicle coating
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-HSA-203977] SAR1 Activation And Membrane Binding - Homo sapiens [Reaction:R-HSA-5694522] Inner coat assembly and cargo binding - Homo sapiens [Reaction:R-HSA-5694527] Loss of SAR1B GTPase - Homo sapiens [Reaction:R-HSA-5694417] SEC16 complex binds SAR1B:GTP:SEC23:SEC24 - Homo sapiens [Reaction:R-HSA-204008] SEC31:SEC13 and v-SNARE recruitment - Homo sapiens [Reaction:R-HSA-203973] Vesicle budding - Homo sapiens [Reaction:R-HSA-5694439] COPII coat binds TRAPPCII and RAB1:GDP - Homo sapiens [Reaction:R-HSA-5694409] Nucleotide exchange on RAB1 - Homo sapiens [Reaction:R-HSA-5694418] RAB1:GTP binds USO1 and GORASP1:GOLGA2 - Homo sapiens [Reaction:R-HSA-5694441] CSNK1D phosphorylates SEC23 - Homo sapiens [Reaction:R-HSA-5694446] BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle - Homo sapiens [Reaction:R-HSA-5694421] PP6 dephosphorylates SEC24 - Homo sapiens [Reaction:R-HSA-5694423] NSF and SNAPs bind cis-SNARE complex - Homo sapiens [Reaction:R-HSA-5694425] NSF ATPase activity dissociates cis-SNARE - Homo sapiens [Reaction:R-HSA-6814831] TBC1D20 binds RAB1:GTP - Homo sapiens [Reaction:R-HSA-6814833] TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2019-03-25
literatureReference	[LiteratureReference:203985] Three ways to make a vesicle [LiteratureReference:211507] Mechanisms of COPII vesicle formation and protein sorting
maxDepth	2
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	COPII-mediated vesicle transport
orthologousEvent	[Pathway:R-MMU-204005] COPII-mediated vesicle transport - Mus musculus [Pathway:R-RNO-204005] COPII-mediated vesicle transport - Rattus norvegicus [Pathway:R-CFA-204005] COPII-mediated vesicle transport - Canis familiaris [Pathway:R-SSC-204005] COPII-mediated vesicle transport - Sus scrofa [Pathway:R-DRE-204005] COPII-mediated vesicle transport - Danio rerio [Pathway:R-XTR-204005] COPII-mediated vesicle transport - Xenopus tropicalis [Pathway:R-GGA-204005] COPII-mediated vesicle transport - Gallus gallus [Pathway:R-DME-204005] COPII-mediated vesicle transport - Drosophila melanogaster [Pathway:R-CEL-204005] COPII-mediated vesicle transport - Caenorhabditis elegans [Pathway:R-DDI-204005] COPII-mediated vesicle transport - Dictyostelium discoideum [Pathway:R-SPO-204005] COPII-mediated vesicle transport - Schizosaccharomyces pombe [Pathway:R-SCE-204005] COPII-mediated vesicle transport - Saccharomyces cerevisiae [Pathway:R-PFA-204005] COPII-mediated vesicle transport - Plasmodium falciparum [Pathway:R-BTA-204005] COPII-mediated vesicle transport - Bos taurus
releaseDate	2010-12-14
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:1028799] Gagneux, P, 2010-11-18
revised	[InstanceEdit:5688570] Rothfels, Karen, 2015-04-17 [InstanceEdit:6791049] Gillespie, Marc E, 2015-08-17
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-204005
summation	[Summation:204016] COPII components (known as Sec13p, Sec23p, Sec24p, Sec31p, a...
updateTrackers	[UpdateTracker:9790187] Update Tracker - [Pathway:204005] COPII-mediated vesicle transport - v35:[removeHasEvent] [UpdateTracker:9789938] Update Tracker - [Pathway:204005] COPII-mediated vesicle transport - v36:[addHasEvent] [UpdateTracker:9783728] Update Tracker - [Pathway:204005] COPII-mediated vesicle transport - v56:[addHasEvent] [UpdateTracker:9911111] Update Tracker - [Pathway:204005] COPII-mediated vesicle transport - v89:[updateContainedRLE] [UpdateTracker:9784409] Update Tracker - [Pathway:204005] COPII-mediated vesicle transport - v54:[add_removeHasEvent, modifyText, updateContainedRLE] [UpdateTracker:9779191] Update Tracker - [Pathway:204005] COPII-mediated vesicle transport - v66:[updateContainedRLE] [UpdateTracker:9778537] Update Tracker - [Pathway:204005] COPII-mediated vesicle transport - v68:[updateContainedRLE] [UpdateTracker:9784009] Update Tracker - [Pathway:204005] COPII-mediated vesicle transport - v55:[updateContainedRLE]

Referrals

(hasEvent)	[Pathway:R-HSA-199977] ER to Golgi Anterograde Transport
(hasEncapsulatedEvent)	[Pathway:R-HSA-5694530] Cargo concentration in the ER
(updatedInstance)	[UpdateTracker:9790187] Update Tracker - [Pathway:204005] COPII-mediated vesicle transport - v35:[removeHasEvent] [UpdateTracker:9789938] Update Tracker - [Pathway:204005] COPII-mediated vesicle transport - v36:[addHasEvent] [UpdateTracker:9783728] Update Tracker - [Pathway:204005] COPII-mediated vesicle transport - v56:[addHasEvent] [UpdateTracker:9911111] Update Tracker - [Pathway:204005] COPII-mediated vesicle transport - v89:[updateContainedRLE] [UpdateTracker:9784409] Update Tracker - [Pathway:204005] COPII-mediated vesicle transport - v54:[add_removeHasEvent, modifyText, updateContainedRLE] [UpdateTracker:9779191] Update Tracker - [Pathway:204005] COPII-mediated vesicle transport - v66:[updateContainedRLE] [UpdateTracker:9778537] Update Tracker - [Pathway:204005] COPII-mediated vesicle transport - v68:[updateContainedRLE] [UpdateTracker:9784009] Update Tracker - [Pathway:204005] COPII-mediated vesicle transport - v55:[updateContainedRLE]

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