Reactome | Inner coat assembly and cargo binding

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Inner coat assembly and cargo binding Show undefined attributes

authored	[InstanceEdit:5685732] Rothfels, Karen, 2015-03-27
category	binding
compartment	[Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:5694524] Rothfels, Karen, 2015-05-21
dbId	5694522
deleted	[Deleted:8855794] Deletion of instance: 203971
displayName	Inner coat assembly and cargo binding
edited	[InstanceEdit:5685715] Rothfels, Karen, 2015-03-27
eventOf	[Pathway:R-HSA-204005] COPII-mediated vesicle transport - Homo sapiens [Pathway:R-HSA-5694530] Cargo concentration in the ER - Homo sapiens
followingEvent	[Reaction:R-HSA-5694417] SEC16 complex binds SAR1B:GTP:SEC23:SEC24 - Homo sapiens [Reaction:R-HSA-5694527] Loss of SAR1B GTPase - Homo sapiens
input	[DefinedSet:R-HSA-5694244] COPII cargo:receptors [endoplasmic reticulum membrane] [Complex:R-HSA-204003] SAR1B:GTP [endoplasmic reticulum membrane] [Complex:R-HSA-203975] SEC23:SEC24 [cytosol]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:204031] COPI-coated ER-to-Golgi transport complexes segregate from COPII in close proximity to ER exit sites [LiteratureReference:204034] Dynamics of transitional endoplasmic reticulum sites in vertebrate cells
maxDepth	1
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	Inner coat assembly and cargo binding
orthologousEvent	[Reaction:R-BTA-5694522] Inner coat assembly and cargo binding - Bos taurus [Reaction:R-PFA-5694522] Inner coat assembly and cargo binding - Plasmodium falciparum [Reaction:R-SCE-5694522] Inner coat assembly and cargo binding - Saccharomyces cerevisiae [Reaction:R-SPO-5694522] Inner coat assembly and cargo binding - Schizosaccharomyces pombe [Reaction:R-DDI-5694522] Inner coat assembly and cargo binding - Dictyostelium discoideum [Reaction:R-CEL-5694522] Inner coat assembly and cargo binding - Caenorhabditis elegans [Reaction:R-DME-5694522] Inner coat assembly and cargo binding - Drosophila melanogaster [Reaction:R-GGA-5694522] Inner coat assembly and cargo binding - Gallus gallus [Reaction:R-DRE-5694522] Inner coat assembly and cargo binding - Danio rerio [Reaction:R-SSC-5694522] Inner coat assembly and cargo binding - Sus scrofa [Reaction:R-CFA-5694522] Inner coat assembly and cargo binding - Canis familiaris [Reaction:R-RNO-5694522] Inner coat assembly and cargo binding - Rattus norvegicus [Reaction:R-MMU-5694522] Inner coat assembly and cargo binding - Mus musculus
output	[Complex:R-HSA-5694523] COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane]
precedingEvent	[Reaction:R-HSA-203977] SAR1 Activation And Membrane Binding - Homo sapiens
releaseDate	2015-09-22
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:1028799] Gagneux, P, 2010-11-18 [InstanceEdit:6791049] Gillespie, Marc E, 2015-08-17
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-5694522
summation	[Summation:5694521] SAR1:GTP recruits the cytoplasmic SEC23:SEC24 complex. SEC24...

Referrals

(replacementInstances)	[Deleted:8855794] Deletion of instance: 203971
(hasEvent)	[Pathway:R-HSA-5694530] Cargo concentration in the ER [Pathway:R-HSA-204005] COPII-mediated vesicle transport
(precedingEvent)	[Reaction:R-HSA-5694417] SEC16 complex binds SAR1B:GTP:SEC23:SEC24 [Reaction:R-HSA-5694527] Loss of SAR1B GTPase

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