Reactome | COPII-mediated vesicle transport

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COPII-mediated vesicle transport Show undefined attributes

created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10911682
displayName	COPII-mediated vesicle transport
eventOf	[Pathway:R-DME-199977] ER to Golgi Anterograde Transport - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:78933] COPII vesicle coating
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-DME-203977] SAR1 Activation And Membrane Binding - Drosophila melanogaster [Reaction:R-DME-5694522] Inner coat assembly and cargo binding - Drosophila melanogaster [Reaction:R-DME-5694527] Loss of SAR1B GTPase - Drosophila melanogaster [Reaction:R-DME-5694439] COPII coat binds TRAPPCII and RAB1:GDP - Drosophila melanogaster [Reaction:R-DME-5694409] Nucleotide exchange on RAB1 - Drosophila melanogaster [Reaction:R-DME-5694418] RAB1:GTP binds USO1 and GORASP1:GOLGA2 - Drosophila melanogaster [Reaction:R-DME-5694446] BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle - Drosophila melanogaster [Reaction:R-DME-5694423] NSF and SNAPs bind cis-SNARE complex - Drosophila melanogaster [Reaction:R-DME-6814831] TBC1D20 binds RAB1:GTP - Drosophila melanogaster [Reaction:R-DME-6814833] TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP - Drosophila melanogaster
inferredFrom	[Pathway:R-HSA-204005] COPII-mediated vesicle transport - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	COPII-mediated vesicle transport
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:56210] Drosophila melanogaster
stId	R-DME-204005
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-199977] ER to Golgi Anterograde Transport
(hasEncapsulatedEvent)	[Pathway:R-DME-5694530] Cargo concentration in the ER
(inferredTo)	[Pathway:R-HSA-204005] COPII-mediated vesicle transport

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