Reactome | SAR1 Activation And Membrane Binding

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SAR1 Activation And Membrane Binding Show undefined attributes

authored	[InstanceEdit:199976] Gillespie, ME, 2007-07-13 20:42:29
catalystActivity	[CatalystActivity:204006] guanyl-nucleotide exchange factor activity of PREB [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:203980] Gillespie, ME, 2007-11-21 20:48:45
dbId	203977
displayName	SAR1 Activation And Membrane Binding
edited	[InstanceEdit:1008194] Jassal, B, 2010-11-10
eventOf	[Pathway:R-HSA-204005] COPII-mediated vesicle transport - Homo sapiens
followingEvent	[Reaction:R-HSA-5694522] Inner coat assembly and cargo binding - Homo sapiens
input	[SimpleEntity:R-ALL-29438] GTP [cytosol] [Complex:R-HSA-203989] SAR1B:GDP [cytosol]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:204031] COPI-coated ER-to-Golgi transport complexes segregate from COPII in close proximity to ER exit sites [LiteratureReference:204034] Dynamics of transitional endoplasmic reticulum sites in vertebrate cells [LiteratureReference:5689331] Concentration of Sec12 at ER exit sites via interaction with cTAGE5 is required for collagen export
maxDepth	1
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	SAR1 Activation And Membrane Binding
orthologousEvent	[Reaction:R-BTA-203977] SAR1 Activation And Membrane Binding - Bos taurus [Reaction:R-PFA-203977] SAR1 Activation And Membrane Binding - Plasmodium falciparum [Reaction:R-SCE-203977] SAR1 Activation And Membrane Binding - Saccharomyces cerevisiae [Reaction:R-SPO-203977] SAR1 Activation And Membrane Binding - Schizosaccharomyces pombe [Reaction:R-DDI-203977] SAR1 Activation And Membrane Binding - Dictyostelium discoideum [Reaction:R-CEL-203977] SAR1 Activation And Membrane Binding - Caenorhabditis elegans [Reaction:R-DME-203977] SAR1 Activation And Membrane Binding - Drosophila melanogaster [Reaction:R-GGA-203977] SAR1 Activation And Membrane Binding - Gallus gallus [Reaction:R-DRE-203977] SAR1 Activation And Membrane Binding - Danio rerio [Reaction:R-SSC-203977] SAR1 Activation And Membrane Binding - Sus scrofa [Reaction:R-CFA-203977] SAR1 Activation And Membrane Binding - Canis familiaris [Reaction:R-RNO-203977] SAR1 Activation And Membrane Binding - Rattus norvegicus [Reaction:R-MMU-203977] SAR1 Activation And Membrane Binding - Mus musculus
output	[SimpleEntity:R-ALL-29420] GDP [cytosol] [Complex:R-HSA-204003] SAR1B:GTP [endoplasmic reticulum membrane]
precedingEvent	[Reaction:R-HSA-5694527] Loss of SAR1B GTPase - Homo sapiens
releaseDate	2010-12-14
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:1028799] Gagneux, P, 2010-11-18
revised	[InstanceEdit:5688570] Rothfels, Karen, 2015-04-17 [InstanceEdit:6791049] Gillespie, Marc E, 2015-08-17
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-203977
summation	[Summation:204028] SAR1-GDP is recruited to the ER membrane by the transmembran...
updateTrackers	[UpdateTracker:9778374] Update Tracker - [Reaction:203977] SAR1 Activation And Membrane Binding - v68:[modifyText] [UpdateTracker:9784220] Update Tracker - [Reaction:203977] SAR1 Activation And Membrane Binding - v54:[addLiteratureReference, modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9778374] Update Tracker - [Reaction:203977] SAR1 Activation And Membrane Binding - v68:[modifyText] [UpdateTracker:9784220] Update Tracker - [Reaction:203977] SAR1 Activation And Membrane Binding - v54:[addLiteratureReference, modifyText]
(hasEvent)	[Pathway:R-HSA-204005] COPII-mediated vesicle transport
(precedingEvent)	[Reaction:R-HSA-5694522] Inner coat assembly and cargo binding

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